Top Tweets for #proDrug
Selective drug activation remains challenging!
This study harnesses #Immunoproteasome activity as a disease-associated trigger, enabling #Prodrug activation in immunoproteasome-expressing cells while limiting effects on healthy cells. @UCLA
#STTT #OpenAccess: https://t.co/hXVJ9gEj3a
“The findings provide the first evidence that a non inhaled, metal-free carbon monoxide #prodrug can suppress #metastasis in multiple #cancer models,” said @WCMCPathology's Dr. Nancy Du on her new paper in Advanced Science (@AdvPortfolio).
https://t.co/nzSUwjsHYq
Article✍️#Heterocyclic modified #paclitaxel #prodrug #nanoassemblies for stimuli-responsive delivery via #lysosomal escape.
From Dr. Sun @ShenyangPharmaceuticalUniversity;
https://t.co/c8HDgpE1UY.
Article✍️#Carboxylated #prodrug of# capsaicin with enhanced #peripheral #nerve permeation mediated by #monocarboxylate #transporters for long-lasting local #anesthesia. From Dr. Zhao @UniversityofAlabama; @UofAlabama; @UMass;
https://t.co/DiPKiYufhI.
Article✍️#Binary #pyroptosis-amplified self-assembling #prodrug #nanomedicine enhances #immunogenicity and inhibits abdominal metastasis in #ovarian #cancer. From Dr. Wang @SouthernMedicalUniversity;
https://t.co/SlJGukzYpi.
Biodynamers as prodrugs with controlled uptake and activity.
| Sangeun Lee @Saar_Uni | @CRS_DeChAt_LC
[Open Access]
#prodrug #biodynamer
https://t.co/PcnP3CHVpl
![JCRnEDITORS's tweet photo. Biodynamers as prodrugs with controlled uptake and activity.
| Sangeun Lee @Saar_Uni | @CRS_DeChAt_LC
[Open Access]
#prodrug #biodynamer
https://t.co/PcnP3CHVpl https://t.co/OUcA4ahTZk](https://pbs.twimg.com/media/G9alkwDaUAANl78.jpg)
Balancing stability and activation: A pseudoparabolic activity spectrum guides fatty acid chain length optimization in prodrug-albumin nanoparticles.
| Qikun Jiang, Shenyang Pharmaceutical Univ. |
[50 days' free access]
#stability #prodrug #albumin
https://t.co/6PZRBIiJx9
![JCRnEDITORS's tweet photo. Balancing stability and activation: A pseudoparabolic activity spectrum guides fatty acid chain length optimization in prodrug-albumin nanoparticles.
| Qikun Jiang, Shenyang Pharmaceutical Univ. |
[50 days' free access]
#stability #prodrug #albumin
https://t.co/6PZRBIiJx9 https://t.co/kzWJYESfQD](https://pbs.twimg.com/media/G8Al_EUa4AA0-yi.jpg)
![JCRnEDITORS's tweet photo. Enzyme-powered micellar nanoreactors enable tumor-specific, cascade-amplified prodrug activation for synergistic oxidation–chemo–immunotherapy.
| Wence Zhou @iLZU1909 |
[50 days' free access]
#micelle #enzyme #prodrug
https://t.co/ifViqqQ9ZC https://t.co/af6Ht4d9w5](https://pbs.twimg.com/media/G7PGIv3bsAAismZ.jpg)
Progress towards a prodrug/enzyme intranasal delivery system for rapid prevention/reversal of seizure emergency.
| Ronald A. Siegel @UMN_Pharmacy |
[50 days' free access]
#NasalDelivery #prodrug #seizure
https://t.co/06akayUWl0
![JCRnEDITORS's tweet photo. Progress towards a prodrug/enzyme intranasal delivery system for rapid prevention/reversal of seizure emergency.
| Ronald A. Siegel @UMN_Pharmacy |
[50 days' free access]
#NasalDelivery #prodrug #seizure
https://t.co/06akayUWl0 https://t.co/0Isa8RRCTu](https://pbs.twimg.com/media/G20P8DSaAAUxWWi.jpg)
Repurposing mesalamine for acute kidney injury through supramolecular assembly.
| Man Kyu Shim @KistPublic | @KoreaCRS
[Open Access]
#prodrug #supramolecule #nanoassembly #KidneyInjury
https://t.co/r3kyKCgiFU
![JCRnEDITORS's tweet photo. Repurposing mesalamine for acute kidney injury through supramolecular assembly.
| Man Kyu Shim @KistPublic | @KoreaCRS
[Open Access]
#prodrug #supramolecule #nanoassembly #KidneyInjury
https://t.co/r3kyKCgiFU https://t.co/4cZRPeVKkq](https://pbs.twimg.com/media/GwoFvOdaAAAEd7n.jpg)
Irinotecan and dexamethasone prodrug co-loaded liposomes for the treatment of breast cancer.
| Yu Zhang, Shenyang Pharmaceutical Univ. |
[50 days' free access]
#prodrug #liposome #codelivery
https://t.co/Ieh2uwOw8A
![JCRnEDITORS's tweet photo. Irinotecan and dexamethasone prodrug co-loaded liposomes for the treatment of breast cancer.
| Yu Zhang, Shenyang Pharmaceutical Univ. |
[50 days' free access]
#prodrug #liposome #codelivery
https://t.co/Ieh2uwOw8A https://t.co/8h7eWnnpGV](https://pbs.twimg.com/media/Gv7kIPJWIAABRZJ.jpg)
Local delivery of IL-12 mRNA and indoximod prodrug potentiates antitumor immunity by increasing T cell effector function.
| Yeu-Chun Kim @kaistpr | @KoreaCRS
[50 days' free access]
#mRNAdelivery #prodrug
https://t.co/BGbH5rf3Uf
![JCRnEDITORS's tweet photo. Local delivery of IL-12 mRNA and indoximod prodrug potentiates antitumor immunity by increasing T cell effector function.
| Yeu-Chun Kim @kaistpr | @KoreaCRS
[50 days' free access]
#mRNAdelivery #prodrug
https://t.co/BGbH5rf3Uf https://t.co/XaE1eREn8o](https://pbs.twimg.com/media/Gu-A-0cXcAAFnXm.jpg)
A cGAS-STING pathway activating cobalt(III) cyclam prodrug for combined chemotherapy and immunotherapy of breast cancer.
| Hanchen Zhang @CAS__Science |
[50 days' free access]
#prodrug #CobaltCyclam #immunotherapy
https://t.co/cKaS0oJuDs
![JCRnEDITORS's tweet photo. A cGAS-STING pathway activating cobalt(III) cyclam prodrug for combined chemotherapy and immunotherapy of breast cancer.
| Hanchen Zhang @CAS__Science |
[50 days' free access]
#prodrug #CobaltCyclam #immunotherapy
https://t.co/cKaS0oJuDs https://t.co/DGX0vinTFT](https://pbs.twimg.com/media/GtrmP2UaoAAw3RG.jpg)
Article✍️#Prodrug-based #combinational #nanomedicine remodels #lipid #metabolism for reinforced #ferroptosis and #immune #activation. From Dr. Jing @SichuanUniversity; @ELSpharma.
https://t.co/zmuUlQoI2M.
Effects of modification modules-adjusted intermolecular forces on docetaxel prodrug Nanoassemblies: From assembly mechanisms to in vivo fate.
| Bingjun Sun, Shenyang Pharmaceutical Univ. |
[50 days' free access]
#nanoassembly #prodrug
https://t.co/Pa7s0kIeR7
![JCRnEDITORS's tweet photo. Effects of modification modules-adjusted intermolecular forces on docetaxel prodrug Nanoassemblies: From assembly mechanisms to in vivo fate.
| Bingjun Sun, Shenyang Pharmaceutical Univ. |
[50 days' free access]
#nanoassembly #prodrug
https://t.co/Pa7s0kIeR7 https://t.co/y270mza3ti](https://pbs.twimg.com/media/GtJ4fUaaQAAfF9v.jpg)
Self-enhanced ROS-responsive camptothecin prodrug nanoparticles elicit safe and efficient intravesical instillation therapy of bladder cancer.
| Qingsong Yu @BeijingChemical |
[50 days' free access]
#prodrug #intravesical
https://t.co/vPZG6B4kUo
![JCRnEDITORS's tweet photo. Self-enhanced ROS-responsive camptothecin prodrug nanoparticles elicit safe and efficient intravesical instillation therapy of bladder cancer.
| Qingsong Yu @BeijingChemical |
[50 days' free access]
#prodrug #intravesical
https://t.co/vPZG6B4kUo https://t.co/bwYuMDcIJW](https://pbs.twimg.com/media/GtJ39hibMAgsOo8.jpg)
Article✍️A #cisplatin #prodrug-based self-#assembling #ozone delivery #nanosystem #sensitizes #radiotherapy in triple-negative #breast #cancer. From Dr. Shi @SichuanUniversity; @ELSpharma.
https://t.co/wF18keEiqD.
Acid-activated mitochondria-targeting nanoprodrug for reactive oxygen species (ROS)-tolerant cancer therapy via antioxidant defense inhibition.
| Shuaidong Huo @xmuchina |
[50 days' free access]
#prodrug #MitochondriaTargeting
https://t.co/IWjoC31Gix
![JCRnEDITORS's tweet photo. Acid-activated mitochondria-targeting nanoprodrug for reactive oxygen species (ROS)-tolerant cancer therapy via antioxidant defense inhibition.
| Shuaidong Huo @xmuchina |
[50 days' free access]
#prodrug #MitochondriaTargeting
https://t.co/IWjoC31Gix https://t.co/NjwX51kruh](https://pbs.twimg.com/media/GrWV6QobsAA_ikm.jpg)
Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.
| Weihai Liu @sysu_1924 |
[50 days' free access]
#prodrug #MetalPhenolicNetwork #ferroptosis
https://t.co/VGiXnXaJNl
![JCRnEDITORS's tweet photo. Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.
| Weihai Liu @sysu_1924 |
[50 days' free access]
#prodrug #MetalPhenolicNetwork #ferroptosis
https://t.co/VGiXnXaJNl https://t.co/EKScRACmix](https://pbs.twimg.com/media/GqyNmGPWYAAE_nY.jpg)
“Capture and kill” circulating fibrocytes by cisplatin prodrug loaded albumin disrupt the progress of pulmonary fibrosis in mice.
| Yang Liu @sysu_1924 |
[50 days' free access]
#prodrug #albumin #fibrocyte #fibrosis
https://t.co/hMOUjm3rJX
![JCRnEDITORS's tweet photo. “Capture and kill” circulating fibrocytes by cisplatin prodrug loaded albumin disrupt the progress of pulmonary fibrosis in mice.
| Yang Liu @sysu_1924 |
[50 days' free access]
#prodrug #albumin #fibrocyte #fibrosis
https://t.co/hMOUjm3rJX https://t.co/Zqwv0uMotF](https://pbs.twimg.com/media/GqS8elZbAAAIfii.jpg)
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