Top Tweets for #proteindna
Our study with @rogoulenko in @NAR_Open shows #DNA flexibility impacts protein binding. Despite kinetic challenges, evolution ensures proteins effectively target and bind DNA. Check out Daniel Philosoph's cover art, hand-painted with real brushes! #ProteinDNA #ProteinStructures
Using machine learning to predict the structure of proteins that bind to DNA and RNA. #MachineLearning #ProteinDNA #ProteinStructures @naturemethods
https://t.co/GOdJyMPiSP
First instance of unfolded to folded ensemble equilibrium demonstrated with exquisite #NMR #CEST experiments and parameters #ChemicalShifts #RDCs by #AshokSekhar and co-workers. A must read!! #IDP #DNA #ProteinDNA
Comprehensive work!! Congrats!!
@MadhurimaKulk @AthiNaganathan
Glad to be a part of this work from Ashok's team at the @iiscbangalore! Structure and DNA binding mechanism of an excited fully folded conformation sampled by an IDP! @MadhurimaKulk @iitmadras @iitmbt @MBU_IISc
https://t.co/otFf0o4lrT
Looking for ways to get ahead in your research? Join CUT&RUN expert Dr. Fang Chen in the CST Learning Lab LIVE! session available on demand. https://t.co/OYyFgYtUTz #proteinDNA #chromatinprofiling
Looking for ways to get ahead in your research? Join CUT&RUN expert Dr. Fang Chen in the CST Learning Lab LIVE! session available on demand. https://t.co/90YTZO8ovQ #proteinDNA #chromatinprofiling
Get #ProteinDNA interaction data in 1-2 days with just ~100K cells with the CST CUT&RUN assay! https://t.co/3IyxtDjLL4
Saving time and money when investigating #proteinDNA relationships sound too good to be true? Learn more about the CST CUT&RUN assay! https://t.co/NyQ04YAM91
Looking for the enzyme and spike-in DNA needed to optimize your CUT&RUN assays? The CUT&RUN pAG-MNase and Spike-In DNA 40366 bundle provides enough enzyme and spike-in DNA to support 50 CUT&RUN assays. Check it out here: https://t.co/28qIvRL9Sx #proteinDNA #chromatinprofiling
Looking for the enzyme and spike-in DNA needed to optimize your CUT&RUN assays? The CUT&RUN pAG-MNase and Spike-In DNA 40366 bundle provides enough enzyme and spike-in DNA to support 50 CUT&RUN assays. Check it out here: https://t.co/Wb3eo1p9SI #proteinDNA #chromatinprofiling
When you need a little extra reagent from the CUT&RUN kit, don’t worry, we got you. The CUT&RUN kit components are available individually here: https://t.co/DW1Mr8Zack #proteinDNA #chromatinprofiling #histones #epigenetics
Another class of #ProteinDNA complexes seen in the #1990s was the enzyme group - e.g., EcoRV endonuclease in complex with DNA (PDB ID 4rve). #DYK the protein DNA interactions vary when binding non-specifically vs when bound to the target site! #pdb50
In the late #1990s #ProteinDNA complexes were seen with neither alpha helices nor beta sheets interact with the DNA. This was classified to an "Other" class - e.g., structure NF-kappaB p52 homodimer-DNA complex. Many of the protein-DNA interactions were water mediated! #pdb50
One of the first #DNA binding protein domains structure determined in complex with DNA was a helix-turn-helix (PDB ID 2ori, repressor of phage 434 bound to a DNA operator, 1989). The domain inserts an alpha helix into the DNA major domain for recognition. #pdb50 #ProteinDNA
✂️➕🏃♀️ How does the CUT&RUN method allow you to map #proteinDNA interactions in 1-2 days with less input sample? Watch our new animation and learn how you can save time at the bench! https://t.co/vOxKJX66BL #chromatinprofiling
Get #ProteinDNA interaction data in 1-2 days with just ~100K cells with the new CST CUT&RUN assay! https://t.co/voZLxLW3Vz
Too few cells for ChIP? CUT&RUN only requires 100K cells! Find out more and check out @CellSignal CUT&RUN reagents here: https://t.co/dn52hrG3Gr #epigenetics #proteinDNA
I would be remiss to not mention the fantastic people in the @RossLevineLab, especially Linde Miles, who were our first partners to test and deploy the #proteinDNA #SingleCell #tapestri assay in #AML primary samples. Very excited to see the culmination of this novel work!
#JobOffer PhD/technical position at the Structural Bioinformatics Group @baldo63 at GRIB @UPFBarcelona @imimat
ℹ️ https://t.co/kPBgc2RDmz #PPI #network #networanalysis #ProteinDNA #interactions #structuralbioinformatics #bioinformatics #TF
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