Top Tweets for #study19

about 4 years ago

26e) #Study19 final OS analysis 🔗https://t.co/xJBFubcTOd #Olaparib vs placebo 📍OS: 29.8 vs 27.8 mos 📍HR 0.73; 95% CI 0.55–0.95 ➕BRCA mutation 📍OS: 34.9 vs 30.2 mos 📍HR 0.62; 95% CI 0.42–0.93 ➖BRCA mutation 📍OS: 24.5 vs 26.6 mos 📍HR 0.84; 95% CI 0.57–1.25

onc_ce's tweet photo. 26e) #Study19 final OS analysis
🔗https://t.co/xJBFubcTOd
#Olaparib vs placebo
📍OS: 29.8 vs 27.8 mos
📍HR 0.73; 95% CI 0.55–0.95

➕BRCA mutation
📍OS: 34.9 vs 30.2 mos
📍HR 0.62; 95% CI 0.42–0.93

➖BRCA mutation
📍OS: 24.5 vs 26.6 mos
📍HR 0.84; 95% CI 0.57–1.25 https://t.co/AejAVYJdOI

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about 4 years ago

26d) #Study19 safety data #Olaparib (OLA) vs placebo ⚠️Most common AEs w/ OLA – nausea, fatigue, vomiting, diarrhea, anemia ⚠️Tx discontinuation = 7 vs 2 patients ⚠️Serious AEs = 18% vs 9% ⚠️Most common serious AE – small intestinal obstruction (1% vs 2%)

onc_ce's tweet photo. 26d) #Study19 safety data
#Olaparib (OLA) vs placebo
⚠️Most common AEs w/ OLA – nausea, fatigue, vomiting, diarrhea, anemia
⚠️Tx discontinuation = 7 vs 2 patients
⚠️Serious AEs = 18% vs 9%
⚠️Most common serious AE – small intestinal obstruction (1% vs 2%) https://t.co/jRrfmDOsgg

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about 4 years ago

26c) #Study19 efficacy data #Olaparib vs placebo 📍mPFS: 8.4 vs 4.8 mos 📍HR 0.35; 95% CI 0.25–0.49; P<0.0001 ➕BRCA mutation 📍mPFS: 11.2 vs 4.3 mos 📍HR 0.18; 95% CI 0.10–0.31; P<0.0001 ➖BRCA mutation 📍mPFS: 7.4 vs 5.5 mos 📍HR 0.54; 95% CI 0.34–0.85; P=0.0075

onc_ce's tweet photo. 26c) #Study19 efficacy data
#Olaparib vs placebo
📍mPFS: 8.4 vs 4.8 mos
📍HR 0.35; 95% CI 0.25–0.49; P<0.0001

➕BRCA mutation
📍mPFS: 11.2 vs 4.3 mos
📍HR 0.18; 95% CI 0.10–0.31; P<0.0001

➖BRCA mutation
📍mPFS: 7.4 vs 5.5 mos
📍HR 0.54; 95% CI 0.34–0.85; P=0.0075 https://t.co/tn5i41riSi

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about 4 years ago

26b) #Study19 👉Baseline characteristics were well balanced 👉➕#BRCA mutation = 51%

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about 4 years ago

26a) #Study19 🔗https://t.co/T6XFgbnp5o 👤P: Patients w/ platinum-sensitive, recurrent high-grade #OvarianCancer (±#BRCA mutation) w/ a CR/PR after ≥2 platinum-based chemo regimens (N=265) 💊I: #Olaparib 400mg BID (n=136) 💊C: Placebo (n=129) 📉O: PFS

onc_ce's tweet photo. 26a) #Study19
🔗https://t.co/T6XFgbnp5o
👤P: Patients w/ platinum-sensitive, recurrent high-grade #OvarianCancer (±#BRCA mutation) w/ a CR/PR after ≥2 platinum-based chemo regimens (N=265)
💊I: #Olaparib 400mg BID (n=136)
💊C: Placebo (n=129)
📉O: PFS https://t.co/sDET6RfXcz

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about 4 years ago

25) Several RCTs have shown a significant ⬆️PFS w/ the use of #PARPi as #MaintenanceTherapy for patients w/ platinum-sensitive recurrent #OvarianCancer (regardless of #BRCA mutation status): 👉#Study19 👉#SOLO2 👉#NOVA 👉#ARIEL3 See 🔓https://t.co/cSrScHkNXY

onc_ce's tweet photo. 25) Several RCTs have shown a significant ⬆️PFS w/ the use of #PARPi as #MaintenanceTherapy for patients w/ platinum-sensitive recurrent #OvarianCancer (regardless of #BRCA mutation status):
👉#Study19
👉#SOLO2
👉#NOVA
👉#ARIEL3
See 🔓https://t.co/cSrScHkNXY https://t.co/YdbGZ8JcFI

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about 7 years ago

Matthew 28:18; Mark 13:24-26; Luke 9:43,44; Luke 4:36; John 17:2; Acts 10:38; Hebrews 1:3; Romans 4:19-21; Ephesians 3:20 #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

POINT 3: THE PREVAILING POWER OF OUR IRRESISTIBLE CHRIST. Mark 4:39-41; Christ has all power to cleanse you of sin, destroy self and keep you in sanctification. #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

Isaiah 9:6,7 John 14:27; Romans 14:17; Ephesians 2:14-17; Psalm 119:165; Isaiah 26:3,4; Isaiah 48:18; Philippians 4:6-9; Romans 16:20 #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

The peace that comes from Jesus is: Present Peace Promised Peace Priceless peace Prevailing peace Perpetual peace Perfect peace Surpassing peace #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

POINT 2: THE PERFECT PEACE IN AN IRRECONCILABLE CRISES. Mark 4:38-40; "Master, carest thou not that we perish? vs38" is not the best pattern of prayer as that was a prayer of anxiety. #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

Acts 3:20-22; Isaiah 46:10,11; Isaiah 55:10,11 You need to know that neither the storms nor opposition of Satan and the society is the greatest thing in your life but the WORD; Jeremiah 1:12 Ezekiel 12:25,28; Hebrews 13:5,6,8; 2Peter 1:19-21 #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

POINT 1: THE PERSONAL PROCLAMATION OF OUR INFALLIBLE CHRIST. Mark 4:35; Mark 5:1; No matter the torrent from the pit of hell or the wrath of the adversary, every words of Jesus shall come to pass because He is God Number 23:19; Deuteronomy 18:18; #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

The study is divided into three points Point 1: The Personal Proclamation of our Infallible Christ. Point 2: The Perfect Peace in an irreconcilable Crises. Point 3: The Prevailing Power of our Irresistible Christ. #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

The story in our text showed the humanity( His sleeping and tiredness) and the divinity (authority over the storm without recourse to any divine being) of Jesus Christ. #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

5. The power of our Saviour vs39 6. The problem of their shallowness vs40 7. The perception of His sovereignty vs 41 #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

Topic: Great Calm through the Master's Intervention. Mark 4:35-41; From the passage we see; 1. The passing over to the other side vs35 2. His presence in the ship vs36 3. The peril of a great storm vs37 4. Their perplexity about His sleep vs38 #MBS #DCLM #GospelOfMark #Study19

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about 7 years ago

Bible Study (July 15, 2019) #DCLM #MBS #GospelOfMark #Study19 https://t.co/Q6rcdH9z7D

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