Ricardo Henriques

@AIOpticalBioLab. Group Leader @itqbnova & H. Prof @LMCB_UCL. #Nanoscopy & #AI for #LifeSciences. #SRRF sensei. #ERCCoG, #EMBO member. Dad. Opinions my own

[Ricardo Henriques @HenriquesLab]

🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars @JDamianMtzR & @Bruno_MSaraiva, inaugural preprint of @_mariod's new lab
https://t.co/4cFH4YoU6E

[Mario Del Rosario @_mariod]

How do you know if a microscopy experiment can actually resolve a biological structure?
Introducing VLab4Mic, a platform that predicts structural resolvability before you go to the microscope
Led by @JDamianMtzR and @Bruno_MSaraiva at @HenriquesLab
https://t.co/fuZHy9zvOs

[Euro-BioImaging ERIC @EuroBioImaging]

#EuroBioImaging Team members are excited to be at #ELMI this week in Coimbra, Portugal, organised by our @PPBioImaging Node. This evening, Luisa Cortes opened the conference on behalf of the organising committee. Looking forward to an exciting programme! 🔬

[Ricardo Henriques @HenriquesLab]

SMLM people, ASSEMBLE!! 🔬 The single-molecule crowd heads to Stockholm, 26-28 Aug, for #SMLMS2026. MINFLUX, DNA-PAINT, blinking dyes, the whole gang. Cracking line-up, registration's open. Come join us 👉 https://t.co/4cRTI16hMC

[Euro-BioImaging ERIC @EuroBioImaging]

Interested in single molecule localisation microscopy? 🔬 Don't miss #SMLMS2026, hosted in by SciLifeLab, KTH and Stockholm University, with contributions from our Swedish NMI Node colleagues!
🗓️ August 26-28 in Stockholm 🇸🇪
More⤵️
https://t.co/QDzF4RXv9p

[Euro-BioImaging ERIC @EuroBioImaging]

Interested in single molecule localisation microscopy? 🔬 Don't miss #SMLMS2026, hosted in by SciLifeLab, KTH and Stockholm University, with contributions from our Swedish NMI Node colleagues!
🗓️ August 26-28 in Stockholm 🇸🇪
More⤵️
https://t.co/QDzF4RXv9p

[RT-SuperES @RTsuperES]

Can your microscope resolve the structure you want to study before you run the experiment?

New #bioRxiv preprint: VLab4Mic predicts structural resolvability in #SuperResolution microscopy, helping choose modality and probe.

Great work from @HenriquesLab.

@RTsuperES ; @EUeic @JDamianMtzR

https://t.co/od0u6X9kBT

[Ricardo Henriques @HenriquesLab]

🔬🚀 Updated #VLab4Mic preprint. Rebuilt the clathrin models from full-length triskelions, dome+flat lattice toy simulations share a common motif. Wanna see how it looks across microscopy methods? (Thank you for the advice Stephane Vassilopoulos)

https://t.co/bdtO1Fh4Jj

[juliette.griffie @GriffieJuliette]

🔬🌟 Join us for SMLMS2026 in Stockholm! 🔬🌟
We’re excited to welcome the advanced light microscopy community to Stockholm August 26–28 2026. Check out our fantastic speaker line-up and register here: https://t.co/cykXEG6BHR

🚨Only 2 weeks left for abstract submission 🚨

[juliette.griffie @GriffieJuliette]

And it is out!!!🚨 Very excited to be sharing SMLMFlow. It has been a fantastic journey with
@sebjbauer
and a great opportunity to work with old friends😜Daniel Sage and Ruby Peters.

[Ricardo Henriques @HenriquesLab]

#ELMI2026 is starting =). Come say hi!!

[Ricardo Henriques @HenriquesLab]

🔬🚀 Preprint update for #VLab4Mic - our super-resolution experiments virtual simulation system. Now installs as a one-click desktop app: no Python, no setup, thanks to the magic of the Jacquemet's lab #LabConstrictor packaging engine
https://t.co/o0NLWlt5uK

[Mario Del Rosario @_mariod]

How do you know if a microscopy experiment can actually resolve a biological structure?
Introducing VLab4Mic, a platform that predicts structural resolvability before you go to the microscope
Led by @JDamianMtzR and @Bruno_MSaraiva at @HenriquesLab
https://t.co/fuZHy9zvOs

[AI-driven Optical Biology Lab @AIOpticalBioLab]

Congrats to @JDamianMtzR on the preprint release of his project #VLab4Mic, a tool able to virtually predict whether a biological structure will be resolved by a chosen microscopy or labeling.🎉

Congrats @Bruno_MSaraiva @_mariod @HenriquesLab

Read at: https://t.co/MnFGQmk97P

[Mario Del Rosario @_mariod]

Can microscopy distinguish a flat from a domed clathrin lattice?
VLab4Mic predicts:
❌ Confocal
❌ AiryScan
✅ STED
✅ SMLM
A simple example of how simulation can guide modality selection before spending microscope time

[Mario Del Rosario @_mariod]

Workflow:
🧬 Import structure
🏷️ Choose labelling strategy
🎲 Simulate realistic stochastic labelling
🔬 Generate virtual images for Widefield, Confocal, AiryScan, STED and SMLM
Helping researchers test experiments before collecting data https://t.co/QsH0LrRtlX

[Mario Del Rosario @_mariod]

Resolution isn't just optics. Structural resolvability also depends on probe size, linkage error, labelling efficiency, steric hindrance and, molecular organisation. VLab4Mic models all of these starting from PDB or AlphaFold structures

[Damian Martinez @JDamianMtzR]

Our preprint is out!! We present VLab4Mic, a platform that predicts structural resolvability for diverse biological structures before any experiments!! https://t.co/5mGixXvrgf

[Ricardo Henriques @HenriquesLab]

@Mech_Morph_Lab @_mariod @JDamianMtzR @Bruno_MSaraiva @wmarkbates @christlet @T_Shakespeare Thank you Elias =), um grande abraço!

[Ricardo Henriques @HenriquesLab]

This closes a loop we opened with #NanoJSQUIRREL (@SuperResoluSian et al., 2018), which mapped where super-resolution images go wrong relative to a reference. #VLab4Mic comes at it from the other end: predicting what's resolvable from known atomic structure before you even image

[Ricardo Henriques @HenriquesLab]

🔬🚀 It's out! Run 100s of imaging experiments before touching a microscope. #VLab4Mic reproduces them in silico from PDB/AlphaFold to help you image right first time. From rockstars @JDamianMtzR & @Bruno_MSaraiva, inaugural preprint of @_mariod's new lab
https://t.co/4cFH4YoU6E

[Mario Del Rosario @_mariod]

How do you know if a microscopy experiment can actually resolve a biological structure?
Introducing VLab4Mic, a platform that predicts structural resolvability before you go to the microscope
Led by @JDamianMtzR and @Bruno_MSaraiva at @HenriquesLab
https://t.co/fuZHy9zvOs

[Ricardo Henriques @HenriquesLab]

Huge thank you to the labs of @christlet, Dylan Owen and Mark Bates, and to @T_Shakespeare, who helped us make it happen. #VLab4Mic also heavily uses data from RCSB PDB, Jonas Ries & Justin Taraska's labs

[Mario Del Rosario @_mariod]

How do you know if a microscopy experiment can actually resolve a biological structure?
Introducing VLab4Mic, a platform that predicts structural resolvability before you go to the microscope
Led by @JDamianMtzR and @Bruno_MSaraiva at @HenriquesLab
https://t.co/fuZHy9zvOs