Sadly, John Midgley, a pioneer in #thyroid diagnostics and co-author of multiple papers by our group, passed away. Read Rudolf Hoermann's (@HoermannRudolf ) obituary at The Guardian:
https://t.co/sJKx1HjIkR
Systems biology of #thyroid_homeostasis: Relational stability of two intertwined feedback loops protects #FT3 concentration despite variations in #thyroid's secretory capacity. https://t.co/WhoChxacoz
In physiology, it is all about homeostasis. Investigating the control system of the hypothalamic-pituitary-thyroid axis including FT3, the biologically more active but often neglected thyroid hormone. https://t.co/QkvLEClMeC
What is subclinical #hypothyroidism? Is it a true disease or a mere laboratory constellation? What we need is a more clinically inclusive definition for subclinical #thyroid disease, more deserving of this name. https://t.co/F9sgcC4eeU https://t.co/7ru42DMov6
@Stofskiftesygdo Far from providing a universal answer by itself, considering its conditional #control function and adaptive relationship with thyroid hormones, interpretation of #TSH requires reconciliation and complementation by #thyroid#hormones in various conditions. https://t.co/c9FHdNRjVZ
Tweetorial on our new paper, part 1: #Thyrotropin (#TSH) concentration is elevated in post-traumatic stress disorder (#PTSD), reflecting an elevated #setpoint of #pituitary-#thyroid feedback control. https://t.co/jtdOch7PpU
#Thyroid homeostasis is a non-ergodic system. Individual factors are from paramount importance in substitution therapy with #levothyroxine, raising problems in substituting one #LT4 preparation with another one. https://t.co/bxImrUpQBe https://t.co/MVmVMBP349
We need to change the definition of this form of #hypothyroidism! Subclinical is no more adequate! In cohort study of 9020 US adults, higher TSH levels associated with increased risk of all-cause mortality. Cardiovascular disease mediated this more in women @AngelaLeung9 .
We see the thyroid gland at the fore front of the defence against the challenge of capacity reduction, with TSH efficiently controlling the glandular hormone depots.
Functional and Symptomatic Individuality in the Response to #Levothyroxine Treatment - an important fact to be considered. https://t.co/v2vEvyQCrh https://t.co/9tfxxFAR4z