Mitch Evan

[Mitch Evan @HowellMitch]

@theproof Simon, wanted to circle back and mention I’ve been impressed by the Nordic Naturals Ultimate Omega Plant-Based algae oil. I’ve not seen EPA/DHA concentrations like this in other algae supplements (though Momentous’ Vegan Omega 3 is excellent as well).

[Mitch Evan @HowellMitch]

@Lpa_Doc Do we see this effect in Type 1 diabetics as well, or do we see this only in cases of insulin resistance?

[Mitch Evan @HowellMitch]

@theproof @nicknorwitz @nicknorwitz , if you’ve completed Whole Genome Sequencing, have you looked into any specific protective variants, such as rs17114036 or s447x in the LPL gene? https://t.co/Di4ppAS8fO

[Mitch Evan @HowellMitch]

@Lpa_Doc For patients with high lp(a) (>125 nmol/L) but low OxPL-ApoB of 1.0-1.5 nmol/L (in the optimal reference range), how would you gauge their overall risk? Could this discordance be explained by larger isoforms?

[Mitch Evan @HowellMitch]

@Lpa_Doc This 2019 research suggests that lp(a) does not increase risk in Africans and Arabs. Has this been replicated in other studies and, if so, what might explain this (larger isoform size, etc)? https://t.co/Q4WiqKkUmX

[Mitch Evan @HowellMitch]

@MurseDarius Will you check your lp(a) to see if there was an impact?

[Mitch Evan @HowellMitch]

@theproof @daveyx2 @YouTube @ethanjweiss Thought this was very interesting

https://t.co/wEma0yqwRq

[Mitch Evan @HowellMitch]

@theproof @Drlipid @JeanVarney Actually, just realized it’s from @Drlipid et al:

https://t.co/ZqGyarNNEv

[Mitch Evan @HowellMitch]

@Drlipid @JeanVarney @theproof To add to @Drlipid, below chart is from a study that shows the population percentiles. You can see the absolute levels for sitosterol at the top. I have a very similar profile: vegan, high sitosterol untreated (5.9) but I take Eze to lower it (now 3.5, still high but better).

[Mitch Evan @HowellMitch]

@theproof Simon, have you found any plant-based supplements that have EPA:DHA ratios higher than 0.50, or even one with just EPA? Like you, I’ve been able to get my O3 index over 8% (thanks to Eimele!). I also supplement with Ahiflower as it is high in SDA which is then converted to EPA

[Mitch Evan @HowellMitch]

@Lpa_Doc Very helpful! I came across this interesting comparison of those two assays and a few others. There does seem to be some variability.

https://t.co/5GMmsrsja8

[Mitch Evan @HowellMitch]

@Lpa_Doc Are you aware of any potential relationship between high serum levels of beta-sitosterol and lipoprotein(a)?