Do the IV fluids we provide to our critically ill patients trash the glycocalyx? This systematic review tackles this issue as we always try to balance benefit and harm. Another example where less could be more. 🎩 tip to the authors!
https://t.co/wtiQFg1wGN
Wearable devices as a game-changer.
New strategies for continuous monitoring in acute medicine & critical care.
✅ Less invasive
✅ Better ICU-to-ward transition
✅ Delirium & pressure injury detection
Read our paper
https://t.co/cPxLsB95r6
#WearableDevices#ICU#MedTech#AI#WD
E.Coli 🐖 sepsis model , shows the time course of neutrophil distribution using PET-tracer [11C]NES targeting Neutrophil Elastase.
Neutrophils+neutrophil elastase :
✅important in sepsis
✅blocking➡️ future treatment in selected situations.
🔓 https://t.co/VCUpZWomal
RescueDoppler, a continuous hands-free carotid Doppler system in a 🐖 model of 🫀 arrest.
✅expected sensitivity of 98% identifying spontaneous circulation during both manual and mechanical chest compressions.
🔓 https://t.co/XWtDEPXIGT
#FOAMEed#CriticalCare
📃Modulation of β3-AR in an 🐀 model of resuscitated septic shock
✅β3-AR is resistant to desensitization
✅its inhibition improves cardiac and vascular function without affecting the short-term survival.
🔓https://t.co/WMCzxGx5cc
Effects of FCV using negative end-expiratory pressures (NEEP), on 🧠 hemodynamics in a 🐖 model of intracranial hypertension.
✅ FCV➕ NEEP appears to be safe
✅ additional tool for severe intracranial pressure episodes.
🔓https://t.co/pWqnIsBeS9
#FOAMed#CriticalCare
Mitochondrial metabolic profiles in DKA ⬇️ cellular O2 consumption vs healthy controls.
✅O2 consumption ⬆️ in cells with thiamine or CoQ10 treatment
✅ Thiamine and CoQ10 could potentially have therapeutic benefits in DKA.
#FOAMed#CriticalCare
🔓 https://t.co/APru05mQuu
📃HyperO2-induced ⬆️ in 🧠 tissue pO2 (PbtO2) ✔️Circulating models 🔮 a ⬇️ PO2
✔️Hb transition relaxed (R) to tense (T) state, driven by deO2 ➡️ pO2 diff. across 🧠 capillaries.
✅ Hb R to T ➡️ for ⬆️ PbtO2 lvls in 🧠 tissue during hyperO2.
🔓 https://t.co/jn5klMxk3D
#FOAMed
◾️In memory of Prof L Gattinoni, towering figure in ICM, profoundly shaping understanding of #ARDS & #ECMO. The “father" of prone position revolutionized MV with a pioneering "baby lung” concept. His legacy will guide/inspire for generations to come.
🔗https://t.co/kjuqkQoPoc
💊TCD-ABx in vitro: antibiotics in dialysis solutions help achieve desired plasma levels with both 'up-' or 'down-dialysis' towards the unbound target concentration.
✅An elegant life hack for antibiotic therapy during CVVHD?
🔓https://t.co/xlOBMMMkNw
#FOAMed#CriticalCare
🔎 Have you seen it? ESICM has a new corporate #identity🎉 Including features like:
🌟A modern #logo
🌐A redesigned #website for clarity & accessibility
🎥Watch our launch video & discover how this evolution shows innovation and progress in our mission to advance #intensivecare
Predictive Tools for Hypotension in KRT:
✅8 studies (2873 pts)
✅Best ML model : XGB
✅PPI & HRV also significant
✅ML + clinical indicators can forecast IDH in AKI pts,
Further validation is needed
🔓https://t.co/Fah8yOD5Kv
#CriticalCare#AKI#MachineLearning
📃Bench study presenting a novel passive expiratory flow regulation device.
🫁The device bench tested demonstrated a ⬇️ in peak expiratory flow rate and dissipated energy, compared to ventilation with unregulated expiratory flow.
🔓https://t.co/WNdyRMzKgB
#CriticalCare#FOAMed