Jacob Sanders

Machine learning, artificial intelligence, neural networks, active learning. Machine Learning Engineer @Osmo_Labs. 🎓 Ph.D. @HarvardGSAS, A.B. @Harvard.

[Jacob Sanders @jacosand]

@NYCHealthSystem @BellevueHosp kept me for 2 extra days because they couldn’t schedule an echocardiogram — then billed me $1000 for those days. Can someone from patient relations please review this?

[Jacob Sanders @jacosand]

@BellevueHosp kept me for 2 extra days because they couldn’t schedule an echocardiogram — then billed me $1000 for those days. Can someone from patient relations please review this?

[Jacob Sanders @jacosand]

@jjanetzko @CU_BMG @CUAnschutz @CUSystem @CUMedicalSchool Congratulations John! Proud of you and happy for you!

[Jacob Sanders @jacosand]

I moved to the West Village in NYC in April, and by now I'm more or less settled in! Who's around NYC and wants to get together?

[Jacob Sanders @jacosand]

I'll be in Boston this coming weekend (Friday, May 31 to Sunday, June 2) for my Harvard reunion, and would love to see people, even if not part of the reunion! Who's around? I'll be there all day Sunday after the reunion ends, and can also possibly make time on other days.

[Jacob Sanders @jacosand]

Proud to be part of this massive #llmhack manuscript invited by none other than my Ph.D. advisor @A_Aspuru_Guzik, and to be part of the pioneering movement to incorporate LLMs into how we solve chemical problems!

[Kevin M Jablonka @kmjablonka]

11. @QaiAlex, @jacosand, @Jiale_Shi, Stefan Bringuier, @BrendenPelkie, Marcus Schwarting use LLMs to convert procedure texts in the ORD to structured JSON

https://t.co/ThlBmSxtB2
https://t.co/JqSmPx5G5U

[Jacob Sanders @jacosand]

@andy_matuschak @octref I don't know either of you, but I randomly saw this and am considering starting this fall! How were the instructors and discussions?

[Jacob Sanders @jacosand]

Thanks also to @OpenAI for an extremely smooth fine-tuning experience!

[Jacob Sanders @jacosand]

My first foray into fine-tuning LLMs to convert textual descriptions of organic procedures into structured JSON data suitable for downstream ML tasks. Was exciting to work with @QaiAlex and the rest of the team at #llmhack and fine-tune the LLM!

[Qianxiang Ai @QaiAlex]

Use LLM to parse free text synthesis recipes to structured data! With only 300 training pairs, the fine tuned model can already pick up chemical identities/amounts and generate valid JSON in ORD schema. Check out our video demo!

[Jacob Sanders @jacosand]

@QaiAlex The model was tuned on data from the Open Reaction Database led by @cwcoley, Abby Doyle, and many others. Thanks to @BenBlaiszik, @kmjablonka, and @andrewwhite01 for organizing #llmhack! Hope to continue working on improving the LLM!

[Jacob Sanders @jacosand]

@davidrliu Congratulations Aditya! I taught him in Chem 30 when he was an undergrad, and it was already clear he was going to do great things in the future!

[Jacob Sanders @jacosand]

@B_randonwright @JanssenUS @ChemRxiv @SarpongGroup Congratulations Brandon! Really beautiful work. I love BCPs too -- fun to study computationally as well!

[Jacob Sanders @jacosand]

@andrewwhite01 @guolin_ke Yes, I have never seen a field with so many potential killer applications of ML and such poor dissemination of data in forms other people can actually use. How many of us are computing the same things over and over and over?

[Jacob Sanders @jacosand]

I had always wondered the meaning of "fan" in "fan_in" and "fan_out" and hadn't been able to find a clear answer. I guess ChatGPT's explanation seems plausible enough to me.

[Jacob Sanders @jacosand]

Another one of my favorite collaborations where we really got to the bottom of a new enzyme mechanism! This one had a lot of unexpected twists and turns! A wonderful experience working with Zhiwen Liu, @XueSherryGao, @sebi_rivera, @davidhsumich, @houk1000, and others!

[Jacob Sanders @jacosand]

One of my favorite molecular dynamics projects to really understand what was going on inside an enzyme! Check it out! A wonderful and rewarding collaboration with @davidhsumich, @houk1000, @VikShende, @nataliaaarose, and others!

[David H. Sherman @davidhsumich]

Congratulations on this outstanding work by @VikShende @nataliaaarose @jacosand and team! Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases https://t.co/7RY82P3mqX @UMLifeSciences @UMichPharmacy @NSFCCHF

[Jacob Sanders @jacosand]

@tweetsbenedict That’s after a couple years. Then you eventually hit the point where you’re in a warm coat because it’s 62 F and freezing.

[Jacob Sanders @jacosand]

@jjanetzko Agree. I know that stretch of North Academy Boulevard from my chem camp days, and it's just tragic. I didn't know there was an LGBT bar nestled right there behind the main thoroughfare. It's a hard place to be LBGT, and it makes me sad to think about who might have been there.

[Jacob Sanders @jacosand]

@jjanetzko @CellCellPress Congratulations!