Jef Boeke

Director, Institute for Systems Genetics, NYU Langone Med Center Retrotransposons, yeast and synthetic chromosomes define research passions

[Jef Boeke @JefBoeke]

@Irina_exh weights to grandfather clock

[Jef Boeke @JefBoeke]

@Airaasayss 11

[Jef Boeke @JefBoeke]

@farman4x 4

[Ran Brosh @BroshRan]

Join @JefBoeke and Carolyn Chapman in this first webinar of the "Rewriting Life" series!!
Register here https://t.co/00Pl3urylh

[Jef Boeke @JefBoeke]

@CWolberger Supergroovy!!!!

[The Dark Matter Project @DarkMatterDNA]

@Nature alert! Our recent paper on the "default states" of the yeast and mouse genomes. Kudos @BCamellato @BroshRan @JefBoeke and the entire Dark Matter Project team!
https://t.co/sqNdrXHnNH

[The Dark Matter Project @DarkMatterDNA]

@Nature hat-trick completed!

3 papers this past year from The Dark Matter Project:

https://t.co/lOHPgZJ92g
https://t.co/z17HQ3NEXl
https://t.co/3nAUPL4S8N

Read more on https://t.co/kqy4bjMO9b

@JefBoeke @BoXia7 @WEIMINZHANG6 @BCamellato @ItaiYanai

[The Dark Matter Project @DarkMatterDNA]

The news on our Nature cover article just keep pouring.
This News&Views from Konkel and Casanova is very good!

A mobile DNA sequence could explain tail loss in humans and apes https://t.co/qT7LKEcU0q

[The Dark Matter Project @DarkMatterDNA]

Mammalian cells repress random DNA that yeast transcribes https://t.co/28KirzEpkw
Out today: N&V by Sean Eddy on our @Nature paper!
@BCamellato @JefBoeke

[The Dark Matter Project @DarkMatterDNA]

CAN YOU READ THIS?
?SIHT DAER UOY NAC
Backwards-written text is hard to read. Turns out that's also true for DNA🧬Check out how @BCamellato wrote the 101-kb HPRT1 locus and its reversed version into the genomes of yeast & mice.
https://t.co/sqNdrXHnNH

[Harmit S. Malik @HarmitMalik]

⁦@Barr_lab⁩ and I enjoy a quiet lull before the storm #TAGC24. Neighboring table informed us that we just missed thousands of screaming kids here for a cheerleading competition. He asked about us; we said we are geneticists, much nerdier with much less eye contact. 🤷‍♂️

[Jef Boeke @JefBoeke]

@jmschreiber91 trust me you will see them

[The Royal Society @royalsociety]

#OnThisDay in 1859, Charles Darwin's landmark book 'On the Origin of Species' was first published. The work is one of the foundations of evolutionary biology, and one of the most important scientific works of the 19th century. #HistoryOfScience

[The Dark Matter Project @DarkMatterDNA]

Out in @Nature!
@WEIMINZHANG6 and the @DarkMatterDNA team developed an efficient method to (biallelically) overwrite the mouse genome with any DNA🧬Huge step to mammalian SynBio. Oh, they also made a COVID-19 mouse model🤧
https://t.co/OGh8DCdUtn

[Jef Boeke @JefBoeke]

This is creepy - according to Dall-E2 it's a "Yeast dressed up as a jack lantern for Halloween. Actually this CREEPY: https://t.co/7Fe9XYfwGg

Congratulations to Yu Jeremy Zhao and all our great coauthors (and thanks Ran Brosh for the yeast/pumpkin hybrid and more...)

[The Dark Matter Project @DarkMatterDNA]

What is 𝐒𝐲𝐧𝐭𝐡𝐞𝐭𝐢𝐜 𝐑𝐞𝐠𝐮𝐥𝐚𝐭𝐨𝐫𝐲 𝐆𝐞𝐧𝐨𝐦𝐢𝐜𝐬?

It's a new approach to study genome (e.g. transcriptional) regulation using 𝐬𝐲𝐧𝐭𝐡𝐞𝐭𝐢𝐜 DNA.
In this 𝐌𝐨𝐥 𝐂𝐞𝐥𝐥 paper, we've applied it to study 𝐒𝐨𝐱𝟐: https://t.co/l1FQh8DEvQ

[Jef Boeke @JefBoeke]

How does #Sox2 get expressed in ES cells? using a downstream enhancer 100,000 bp away... Check out some remarkable NextGen enhancer bashing by @BroshRan with help from the amazing team in Matt Maurano's lab and the @DarkMatterDNA project... https://t.co/eL9fVHdCNq

[Jef Boeke @JefBoeke]

Hey everybody, the Dark Matter project just went social media whole hog!!! @DarkMatterDNA and don't forget ... https://t.co/oPk1JcZ1xa

[Jef Boeke @JefBoeke]

check it out ... synbio for future health ... https://t.co/QRH0dW1WpS

[Oded Rechavi @OdedRechavi]

Recombination
https://t.co/zkX3QxIhGM