Jeremy Yap

PhD candidate @inflammasomelab at @IMBatUQ. Interested in the cellular incendiary grenade that is the inflammasome 🔥

[Jeremy Yap @jeroptosis]

I am super honored to co-author a commentary on Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19 with @VirusesImmunity and @MiyuMoriyama from @YaleMed. Here's to effective therapies and vaccines!
https://t.co/DFHSsOMKkq

[Prof. Akiko Iwasaki @VirusesImmunity]

This time, we developed a nasal booster vaccine for influenza viruses. In this preprint, @MiyuMoriyama et al. show that nasal boosters with unadjuvanted hemagglutinin protein induce sterilizing immunity in mice against flu. (1/)
https://t.co/JYkm9h6xeR

[Malvina Pizzuto @MalvinaPiz]

It is out! 🚨 Phosphorous-free bacterial lipids can switch between pro- and anti-inflammatory depending on context!🔬 #Immunology #LipidBiology @PelegrinPablo @inflammasomelab
A big thanks to the reviewers and editors. It was a laborious but smooth process🥳

[Alerie Guzman de la Fuente @AlerieDe]

2-years after starting the transition to PI and building upon my own mistakes and advice from multiple generous and fantastic mentors and colleagues, I have attempted this Career Article published at @ImmunolCellBiol
https://t.co/daE93E42Yr

[Nature Rev Immunol @NatRevImmunol]

Inflammasome components as new therapeutic targets in inflammatory disease https://t.co/gqBaNNZoDU

[Kaiwen Chen @_kaiwenchen]

A number of new studies on gasdermin were published recently. @broz_lab and I put together a review to summarise and discuss our current understanding of gasdermins during cell death and inflammation.
https://t.co/j2ApEYIfp9

[Arif Ashraf @aribidopsis]

🔬🔬🔬

***Imaging TurboID fusion proteins with streptavidin***

Beyond BioID: Streptavidin outcompetes antibody fluorescence signals in protein localization and readily visualises targets evading immunofluorescence detection @eLife

https://t.co/IsY2otXTW3

[Larisa Labzin @LarisaLabzin]

I'm very proud to have co-authored this review on antibodies and infection with my twitterless PhD student Tyron Esposito, @TheWellsLab and @HendersonLab. Please check it out 👇

Mechanisms of antibody-dependent enhancement of infectious disease | Nature Reviews Immunology

[Kaiwen Chen @_kaiwenchen]

The first paper from the Chen lab is out! Congrats
@seejie_yow on dissecting the cell type-specific requirements for Yersinia-induced pyroptosis in neutrophils and macrophages! https://t.co/ljYAov6A7l

[Jeremy Yap @jeroptosis]

@_kaiwenchen @seejie_yow Amazing! Congrats @seejie_yow & @_kaiwenchen !!! 🥳👏🏻

[Today In History @historigins]

Places on Earth that don't seem real - thread 🧵

1. Namibia, where the desert meets the ocean

[Jeremy Yap @jeroptosis]

@LabListon The reality is, as much as I would love to network with the highest ranking members in any department, they are often too popular and busy to entertain a small-fry grad student.

[Kim Samirah ROBINSON @KimSamirah]

Becoming a new PI is hard but is made 100% easier when you're surrounded by wonderful colleges. Never walk alone.

My amazing colleague @dave_boucher and I just published our first work together ❤️
#inflammasomes #epithelial innate immunity @YBRI_UoY

https://t.co/I8INsHQBau

[Dave Boucher @dave_boucher]

InflammaZoom is back! Join us on the 26th of February 2pm (GMT) for 2 exciting talks. We will be hosting Prof Petr Broz @broz_lab @DIB_UNIL and Dr Paras Anand @anandparas @imperialcollege . @abcam @InflammaZoom Sign up here https://t.co/B4rz3S4IH4

[Jeremy Yap @jeroptosis]

@rayner_beth @MikaelaKeyser Thanks Beth & Mikaela 😁

[Jeremy Yap @jeroptosis]

More evidence of the intimate (and often intricate) relationship between cellular redox regulation and inflammasome activity.

[ICB - the journal @ImmunolCellBiol]

Research highlight: @jazzy_yup, @S_Emming & Prof Kate Schroder @inflammasomelab comment on work from Zhang et al. providing key insight into regulatory mechanisms governing NLRP1 activation and potential for structure-based anti-inflammatory drug design https://t.co/pjOTkl9xUj

[Jeremy Yap @jeroptosis]

🤯

[Tessa Campbell @ScientistTess]

I once saw someone refer to their PBMC ficoll process taking 2.5 hrs so I want to put our lab's SOP out there. Saves tonnes of ⏱ without compromising quality 👌

Just pop and drop those pipettes of ficoll 😎

[Nature Reviews Microbiology @NatureRevMicro]

The HIV epidemic 40 years on

https://t.co/MssbIaOvUF

@LindaGailBekker highlights the progress that has been made over the past 40 years since the discovery of HIV, and discusses the commitment needed to end the HIV/AIDS epidemic as well as ongoing challenges.

[Dan Bachovchin @DBachovchin]

Our latest work by @michaelgeeson and @jeffreychsiao shows that NLRP1 associates with TRX1 using a transient disulfide bond. Their discovery showcases the predictive power of AlphaFold-Multimer! https://t.co/s6X7GJ09Ur

[Jonathan Kagan @jkagan1]

STING is a membrane channel.
Findings help explain why STING has all those transmembrane domains, a question that has puzzled many (including me) for years. Kudos to Hacohen, Irvine and Bingxu Liu on this interesting discovery.
@BingxuL @MIT
https://t.co/mUloW50Jd1

[Clare Bryant ([email protected]) @ClareBryant13]

Inflammazoom bat special soon with Linfa Wang and Matae Ahn