JMCC Plus

Open Access journal of the International Society for Heart Research.

[JMCC Plus @JMCCPlus]

Really nice work out from Bagshi et al from the @blackwood_erik group.

Ever wondered how patients exposed to #doxorubicin can have an increased risk of adverse events. This new paper gives us some important insights!

#CardioOncology

https://t.co/fsOqbkAlYh

[erik_blackwood @blackwood_erik]

Check out our pub in ⁦⁦@JMCCPlus⁩ led by amazing MD/PhD student Sukriti Bagchi! It’s got something for everyone: fibrosis, cellular memory, anthracyclines! ⁦@NEH_CVRTI⁩ ⁦@uofunuip⁩ ⁦@UtahCMH⁩ ⁦@ISHR_NAS⁩ ⁦@ECI_ISHR⁩ https://t.co/etsWe061x8

[JMCC Plus @JMCCPlus]

ISHR World Congress abstracts are now published in JMCC Plus! 🎉

Showcasing global advances in cardiovascular research.

https://t.co/ucUakadf0R

[erik_blackwood @blackwood_erik]

Registration is now open!!! Join us for ISHR NAS 2026! ⁦@ISHR_NAS⁩ ⁦@ECI_ISHR⁩ ⁦@JMCCardiology⁩ ⁦@JMCCPlus⁩

[JMCC Plus @JMCCPlus]

Stuck between a ROCK2 and a hard place?
New research just out shows selective ROCK2 inhibition reduces microvascular obstruction after myocardial I/R but doesn’t limit infarct size. Highlights distinct roles for ROCK isoforms in #cardioprotection. 🫀🔬

https://t.co/ZXWTmIZxk5

[JMCC Plus @JMCCPlus]

🫀New research demonstrates that high-throughput, label-free optical oxygen measurements can assess adrenergic effects in iPSC-derived #cardiomyocytes.

Paired with all-optical #electrophysiology, this enables scalable, human-based preclinical testing.

https://t.co/LfafnjqaeZ

[JMCC Plus @JMCCPlus]

🫀🦠 How does #COVID19 damage the heart?

New research from Gross et al. using human iPSC-derived #cardiomyocytes uncovers cellular responses to SARS-CoV-2, shedding light on mechanisms of cardiac injury.

https://t.co/bVVMB1iXk2

[JMCC Plus @JMCCPlus]

💓 New research from Achlaug et al. @TechnionLive reveals how cancer-driven cytokine signalling improves cardiac function and reduces fibrosis.

Tumour–heart crosstalk with major therapeutic implications

https://t.co/z4HKXzYf5u

#CardioOncology #Immunology #Fibrosis #Research

[Davor Pavlovic @PavlovicDavor]

We look forward to welcoming you in #Birmingham
@VisitBritain @ISHR_ES @unibirmingham

[JMCC Plus @JMCCPlus]

🚨 New paper alert! Feder et al. have recently shown that persistently increased #CaMKIIδ autophosphorylation drives pathological sarcoplasmic reticulum #calcium loss in a murine model of #doxorubicin-induced #cardiomyopathy. 💔➡️📉 Check it out:
https://t.co/yRvWIxMYnk

[JMCC Plus @JMCCPlus]

Rab10 to the rescue! 🦸‍♂️🫀!

New study from Xu et al. in the December issue shows how this tiny protein helps keep harmful heart growth in check.

Read more at:
https://t.co/8Y0B6b9Qb1

#CardioProtection #Hypertrophy #CardioX

@IshrMci @ISHR_ES @ISHR_NAS @ISHR_LAT @ISHR_AUS

[JMCC Plus @JMCCPlus]

🧪 Just out: a new #review of Rac1-driven signalling in cardiomyocytes — covering #hypertrophy, #arrhythmia and #redox stress.

A must-read for anyone in cardiac research! 💙

#Cardiology #HeartResearch #SignalTransduction

https://t.co/LXBYCA6ev1

[JMCC Plus @JMCCPlus]

Great new paper just out! Interested in how #insulin may promotes pro-inflammatory changes in the transcriptome of #atherosclerotic plaques? Check it out!

@IshrMci @ISHR_ECI @ISHR_NAS @ISHR_ES @ISHR_LAT @JMCCardiology @ISHR_AUS

[Angelle (Dr. Gelle) @JustGelle]

Insulin use promotes pro-inflammatory changes in the transcriptome of ... https://t.co/4bZHiO9tEd

Excited to have this published in
@JMCCPlus special issue. Grateful to the entire team I was able to work with and learn from, starting with Dr. Woods.

[JMCC Plus @JMCCPlus]

On your way to #AHA or just looking for some weekend reading?

Check out the latest paper from Warren et al @thisisUIC who uncovered region-specific metabolic and signalling changes in the endocardium vs epicardium in a mini-pig model of #HCM 🫀🫀

https://t.co/3l1MokVbic

[JMCC Plus @JMCCPlus]

New work from Daoud et al. shows that removal of YAP/TAZ from vascular smooth muscle cells triggers inflammation and immune activation- indicating these factors as essential in vascular health.#vascularbiology
https://t.co/DfB7HaFwK0

@lunduniversity @JordanUni_Int @TU_Muenchen

[JMCC Plus @JMCCPlus]

We often treat #diabetes and #heart #disease separately — but they’re connected🫀.

A recent study from Srinivas, Alluri et al. from @ODU shows that removing CHOP in β-cells protects against both metabolic dysfunction and cardiac fibrosis in T2D mice.

https://t.co/iCOSGG4LST

[JMCC Plus @JMCCPlus]

🫀 New in JMCC Plus!

Age, sex & vessel region shape vasomotor function in the descending thoracic #aorta — with #endothelial integrity & relaxation declining with age.

Want to know more- check out Saemann et al.:

https://t.co/ffgaTDTtA2

#VascularBiology

[JMCC Plus @JMCCPlus]

New work from @nicoleyorkova and the group of @dr_swayne charts how H9c2 heart cells change shape, signal, & express genes during differentiation—revealing both their promise & limits as #cardiomyocyte models.

#CardioTwitter @JMCCardiology
@LeighWicki

https://t.co/7lknrbethj

[Journal of Molecular and Cellular Cardiology @JMCCardiology]

Early Career Investigators, don't miss your chance to present an abstract at the ISHR-NAS ECI Webinar. Deadline to submit an abstract is Oct. 31. Details at https://t.co/N8esMPEnLw

@ECI_ISHR @ISHR_ECI @ISHR_NAS @JMCCPlus

[JMCC Plus @JMCCPlus]

Ever wondered how #Calcium channels cluster in #iPSC derived #Cardiomyocytes?

New work just published from Schwenzer et al. should put your mind at rest as they investigated just that!

Check out the latest paper for more information

https://t.co/KZWLOTcKcC

@uniGoettingen

[JMCC Plus @JMCCPlus]

Looking for some weekend reading? 📜

New work from from the @HeartInstitute show how metabolic substrates regulate effects of Wnt/β-catenin signaling in #cardiomyocytes, specifically affecting regulation of #Connexin43

@WenbinLiang2 @PeterPLiu_MD

https://t.co/HcXD2jQjTk