J. M. Perkins

Stories. Essays. Magic. Monsters. Games. Etc.

[J. M. Perkins @JMPerkins]

@inflammateomnia Very true, though how do you draw the line between scifi stories that came to pass vs hypotheticals that can't happen?

[J. M. Perkins @JMPerkins]

Since I decided to stop eating them, I realize that pigs are apparently the breakfast meat animal in my culture.

[J. M. Perkins @JMPerkins]

@QiaochuYuan @wholebodyprayer @KeturahAbigail This is super helpful to me to understand what has sometimes rubbed me wrong about certain radical self expression folks or some folks who sometimes retreat to a fortress of calcified social self diagnosis; "can you (are you) doing what you can to arrange to the other?" Thank you

[J. M. Perkins @JMPerkins]

We need like a pangram for what percentage of a political opinion is a psyop. For what percent of your values are produced by a Disney movie. And someday, what percentage of your memory came from generative ai.

[J. M. Perkins @JMPerkins]

@thinkingshivers Those are good rocks. Could see a RPG protgonist hella walking up a road made of those rocks, or many other delightful purposes.

[J. M. Perkins @JMPerkins]

@Austen I briefly read this as cyber*crabs* and for a moment the world was stranger and a bit more alarming

[J. M. Perkins @JMPerkins]

@cremieuxrecueil Soon, it will just be clankers A/B testing the bespoke shards of carefully honed outrage.

[J. M. Perkins @JMPerkins]

@myhandle Antquihire

[J. M. Perkins @JMPerkins]

@QiaochuYuan For me, what it seems most suggestive is that we keep thinking of ourselves as having 'general' intelligence but no, we have a particular shape to the way our intelligence tends to flow; the other systems we grow and entangle ourselves with will also be particular & specific.

[J. M. Perkins @JMPerkins]

@leashless So, in actual human life circumstances, to do a proper 'observe' phase that doesn't overly simplify something vital would take longer than your lifespan?

[J. M. Perkins @JMPerkins]

Pro-tip, if you want to counteract AI's tendency towards sycophancy, nudge to to be gayer (use gay/drag coded language like 'read me to filth'). I think this pierces the weave around 'be helpful and nice' by invoking a social justice preferred class.

[J. M. Perkins @JMPerkins]

Is tipping the most common info hazard?

[J. M. Perkins @JMPerkins]

We are living in either paranoid schizophrenic heaven or hell I can't figure out which...

[Zane Koch @zanehkoch]

ok actually insane paper published yesterday

a research group in Korea built a gene switch you can control wirelessly using electromagnetic fields

they exposed mice to 60 hz EMF (same frequency as your wall outlet) using a pair of large coils that generate a uniform magnetic field around the animal, for cyclic 3-day on / 4-day off pulses

they showed this could:
- activate OSK to do epigenetic reprogramming in progeroid and aged mice, extending lifespan and reversing aging markers across multiple tissues
- conditionally switch on mutant amyloid genes only in aged mouse brains, letting them separate aging effects from amyloid effects to study AD biology in a way previous models couldn't

no drugs, no impacts, just a magnetic field from outside the body

[J. M. Perkins @JMPerkins]

I'll be bummed it Coyote vs Acme ends up bad...

[J. M. Perkins @JMPerkins]

@BecomingCritter I think the biggest thing it doesn't quite address is if we could use other means to reach for the benefits without the cost (maybe psychedelics?)

[J. M. Perkins @JMPerkins]

@BecomingCritter this is a good ong now talk arguing why alcohol might be societally adaptive (even if it's poison). Basically, it's probably good sometimes to damper the prefrontal cortex for creativity & signaling cognitive disarming for a lot of social goods. https://t.co/IXIcja0dUg

[J. M. Perkins @JMPerkins]

@visakanv @the_wilderless Oooh I like this, really explanatory take

[J. M. Perkins @JMPerkins]

So what deepblue was to chess, mythos is to hacking?

[J. M. Perkins @JMPerkins]

@pmarca I worry that's how we've been running our genetics and other critical systems...

[J. M. Perkins @JMPerkins]

The actionable insight might just be: stay weird enough to have options, stay fed enough to stay in the game.