JPGN Reports

Peer-reviewed, open access journal. Novel case reports, articles, images, etc — for the field of Pediatric Gastroenterology, Hepatology, Pancreas, Nutrition.

[JPGN Reports @JPGNReports]

Rannulu et al: #Crohns + #PeutzJeghersSyndrome in ONE child?! 🤯

Only the 5th case ever reported
Overlapping symptoms, dual cancer risk, and zero clear guidelines

How do we screen/manage these pts? 👀🔥

#PedsGI #IBD #PJS #STK11 #MedTwitter #GITwitter

[JPGN Reports @JPGNReports]

Pierce et al just dropped data on #PraderWilliSyndrome + gut 👀 #Constipation ~ 2x general population & FI in 35%
but HALF of parents miss it.

Are we under-recognizing?

#PedsGI #MedTwitter #PWS #GITwitter #PWSAwareness

🔗 https://t.co/DEo1Yw4p5X
https://t.co/DEo1Yw4p5X

[JPGN Reports @JPGNReports]

Alshammari et al 🚨1st ped case: #HodgkinLymphoma at the ampulla of Vater?!

obstructive jaundice 😳 + #dupilumab + hyper-IgE = dx curveball Rare, tricky, & treatable

#PedsGI #Endoscopy #HodgkinsLymphoma #LymphomaAwareness #Pathology #GIPath #ERCP

🔗 https://t.co/vhr4HPqbJ4

[JPGN Reports @JPGNReports]

Bryan & Leibowitz: infant with FTT + hematemesis → gastrin 1700 👀

Hidden culprit? Gastric duplication cyst missed on initial imaging 🤯
Resection cured it.

#PedsGI #GITwitter #Endoscopy #Ulcer

🔗 https://t.co/2bXCSoUT52

[JPGN Reports @JPGNReports]

Zeisler et al just pushed the limits of peds #endoscopy 👀

Successful #CapsuleEndoscopy in an 8 mo (7.5 kg!) - no prep, no patency capsule, bedside placement & it found the bleed 🎯

Tiny patient, big impact for #VCE in infants 🔬

#PedsGI #GITwitter
🔗 https://t.co/MNNZX5MUaD

[JPGN Reports @JPGNReports]

Nguyen et al just changed the game? 🤯

#Upadacitinib for #eczema → sustained clinical + histologic #EoE remission even OFF #dupilumab 👀

One drug, 2 diseases?? Signal for JAKs in EoE? 🔥

#PedsGI #JAKinhibitors #AtopicMarch

Read: https://t.co/WjkzuivH44

[JPGN Reports @JPGNReports]

🚨 #Wilsondisease without the “classic” clues?!

Palan et al: whole-exome sequencing cracked a tricky case
no KF rings, borderline copper, AIH/MASLD mimic - Dx unlocked 🔬➡️

#PedsGI #Hepatology #LiverTwitter #LiverPath

🔗 https://t.co/iWhmBGKUAp

[JPGN Reports @JPGNReports]

Dunn et al just asked teens with #CeliacDisease what they actually want & it’s NOT top-down mentoring 👀

Peer matches, shared lived experience, hybrid hangouts = better connection + QoL

Are we designing programs wrong? 🤔

#PedsGI #GITwitter #GlutenFree

https://t.co/jfFw76qGet

[JPGN Reports @JPGNReports]

Mosher et al: “itching” teen wasn’t #AIH - it's #WilsonDisease 🤯

Steroids failed → check copper + KF rings → rapid fix with chelation
Atypical WD = don’t miss it 👀

#PedsGI #MedTwitter #LiverTwitter #Hepatology #LiverPath

🔗 https://t.co/jiHiZrIpcb

[JPGN Reports @JPGNReports]

Houmani et al 🔥 Peds #PepticUlcer ≠ just #HPylori

📊 14% prevalence on EGD
💊 Meds = BIGGEST risk (OR ≈7!)
🩸 #GIBleed matters
👶 Older kids at higher risk

Rethink what’s driving ulcers in kids 👀

#PedsGI #GITwitter

🔗 https://t.co/NprkXsRrXX
https://t.co/NprkXsRrXX

[JPGN Reports @JPGNReports]

Kawaguchi et al just dropped a gut twist you didn’t see coming 👀

Preterm infant + high-output stoma → ➕ glutamine + PHGG = ↓output, ↑feeds, ↑villi + #microbiome shift 🔬

Is this the next #intestinalrehab hack? 🤯

#PedsGI #NeoTwitter #ShortBowelSyndrome
🔗

[JPGN Reports @JPGNReports]

Litwin et al 🔍 When a “pseudocyst” isn’t..

11yo with #pancreatitis → cyst → yrs later = Solid pseudopapillary epithelial neoplasm 😳

🔑 atypical course + solid components on MRI

Pancreatic tumors can masquerade!

#PedsGI #Pancreas #PancreasTwitter #MedTwitter

🔗

[JPGN Reports @JPGNReports]

Kurkal & Gupte 🚨 New way to classify liver disease in #ARPKD kids!

Moving beyond kidney-focused systems → simple, clinically meaningful categories (#CSLD vs #CiSLD) 🌍

90%+ expert agreement. 👀

#PedsGI #LiverTwitter #GiTwitter
Read: https://t.co/j7hvlbDyE0

[JPGN Reports @JPGNReports]

Agrawal et al put #AI to the test in pediatric #celiac 👀🤖

#ChatGPT vs #Gemini: high accuracy ✅
But readability? 🚨 Too advanced for most patients

Great info ≠ understandable

Read: https://t.co/V1LlaSMSrT
#PedsGI #MedEd #AIinMedicine

[JPGN Reports @JPGNReports]

🚨 Hematemesis + syncope and the dx? #GastricCancer 😳

Wang et al drop a rare ped #SRCC case (<1% of childhood cancer) with a BIG twist: 5-year disease-free survival after surgery 👀

#PedsGI #RareDisease #MedTwitter
Read: https://t.co/Xlr6D0oSeH

[JPGN Reports @JPGNReports]

Dudzik et al just flipped the script 👀

Anti-TNF → triggers #EGID… then #benralizumab wipes #eosinophils FAST and restores remission 🤯

Dual #biologics (vedolizumab + benralizumab) in a kid with #Crohns?

#PedsGI #GiTwitter #MedTwitter

Read: https://t.co/iuDTis3aLM

[JPGN Reports @JPGNReports]

🚽💩 Parents guessing what’s “normal”? Think again

Huijgen et al: Only 60% of kids are toilet trained by 3 yrs 😳
& bowel habits? Way more variable than you think early on

Overcalling vs missing #constipation?

#PedsGI #ToiletTraining #GITwitter

Read: https://t.co/soCLPGuquQ

[JPGN Reports @JPGNReports]

Greenhall et al 🚨 #Upadacitinib in Peds #IBD looks promising
BUT 44% relapsed after stepping down 😬

Good news? 86% regained response with re-escalation 🔄

Dosing strategy may need a rethink 👀

#JAKinhibitors #GITwitter #IBDTwitter #MedTwitter

Read: https://t.co/miG1am5OVM

[JPGN Reports @JPGNReports]

Rare but real: #collagenous #gastritis in kids 🚨

Emiliani et al: 7 pts, ALL with anemia + gastric nodularity
➡️ symptoms improve, histology doesn’t 😳

Iron helps. Budesonide? Not so much.
Are we treating labs or disease? 🤔

#PedsGI #GITwitter #RareDisease
Read:

[JPGN Reports @JPGNReports]

🚨 Missed for YEARS?!

Pendleton et al: 2 wild cases of 3β-HSD7 deficiency dx in adolescence - no classic #cholestasis, just unexplained fat-soluble vitamin deficiencies 👀

Are we missing #BASD in teens?

#PedsGI #Hepatology #LiverTwitter #MedTwitter

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