(((Kathie)))

Researcher, life enthusiast despite living the #LongCovid life. #ME
tired of the theocracy.

[(((Kathie))) @KathieKaneW]

Our daughter Chloe is bravely facing breast cancer at just 28. We need your help to cover her medical costs. Please donate or share to help her focus on healing. ❤ https://t.co/S6Oh9WokaI #ehlersdanlos #eds #breastc

[(((Kathie))) @KathieKaneW]

Hello everyone, I started a fundraiser on GoFundMe and would appreciate your support for my 28 year old daughter Chloe Kane-Willis who has been diagnosed with breast cancer. https://t.co/fX7JYFytZ1

[(((Kathie))) @KathieKaneW]

@brownie_terror @FCC I'm in northern MI

[(((Kathie))) @KathieKaneW]

@TheChadColby @Verizon I have a sim card and mine is down too

[Putrino Lab @PutrinoLab]

Thank you @ChrisCuomo for having me on to discuss the effects of #covid19 and #longcovid on the immune system and general health. Remember: we have no evidence to suggest that even mild #COVID infections are “harmless”, but we do have evidence to the contrary. Prevention is key.

[Prof. Akiko Iwasaki @VirusesImmunity]

Sharing our new study by @keylas3, @SilvaJ_C, Rafael Bayarri Olmos et al (with T. Horvath & @PutrinoLab) showing that a passive transfer of IgG from patients with #longCOVID into mice recapitulates ⬆️ pain and other symptoms 🧵 (1/)

https://t.co/J5I22Y4fnn

[(((Kathie))) @KathieKaneW]

@MelanieWeckert @CortJohnson I was sure that was what I had in 2023 as my long covid started to make it impossible for me to move. I also became stiff. Mestinon didn't work for me. No AB either.

[Monica Verduzco-Gutierrez, MD @MVGutierrezMD]

At #ISPRM2024 I found an Aussie in his native habitat. (Coffee shop) 🦘🇦🇺☕️
I am in awe of all @PutrinoLab is doing with NeuroRehab & #LongCovid. He is passionate & he is diligently working to find treatments!
I also had to give him some CBT for his ankle. It’s healed now 😜

[Putrino Lab @PutrinoLab]

I’ve been trying to think my way out of my Achilles tendinitis for 3 whole days and I’m starting to think that maybe it is actually a maladaptive response to my fear of running. @MVGutierrezMD I’m starting to suspect the same about your “sore knee”…group therapy?

[María Richardson @_diatoma]

We desperately need folks like @jonstewart @iamjohnoliver to cover the scandalous history & present of #MyalgicEncephalomyelitis & #LongCovid. Misinformation is the norm; it falls on us patients to educate doctors, family, friends. Good media coverage can change this.

[(((Kathie))) @KathieKaneW]

Long covid PT. Multifocal osteonecrosis occurred in ppl from 1st SARS epidemic. https://t.co/NJlrWjpOik

Now experiencing for myself. So far 4 joints destroyed 2 hips 2 shoulders all needed total replacements. Painful joints? get them imaged!

[(((Kathie))) @KathieKaneW]

@ahandvanish have you heard of mutifocal osteonecrosis in long covid patients? It occurred w SARS https://t.co/NJlrWjpOik

I have 4 sites now 2 shoulders + hips abt to look at knees. All needed total replacements. LC 1st wave. Check joints ppl

[Hannah Davis @ahandvanish]

🥹

[Eric Topol @EricTopol]

This #LongCovid review ranked #3 of all 472,802 peer-reviewed papers tracked by @altmetric for 2023; it has had >1.2 million downloads/accesses, which reflects both the vital importance of the condition and the great work by @ahandvanish @LisaAMcCorkell @julialmv

[Rob Wüst @RobWust]

@BraedenCharlton To reduce the skeletal muscle abnormalities (reduction in mitochondrial function, muscle damage and more microclots), we can only recommend to avoid strenuous exercise for now. Every patient likely has a different threshold for induction of post-exertional malaise. 8/n

[(((Kathie))) @KathieKaneW]

@RobWust @BraedenCharlton Rob thank you for this important study. Based on this thread I wanted to know if there is lasting damage or any damage to the muscles among those w long covid who have PEM. Is it just symptoms that are worse or actual damage? TY

[Rob Wüst @RobWust]

@BraedenCharlton This study contributed to our understanding of muscle pain, fatigue and weakness in patients, and provides a biological substrate for the disease. It doesn’t directly point to the cause of the disease, but highlights that exercise can worsen symptoms in patients 7/n

[Rob Wüst @RobWust]

@BraedenCharlton We tested whether viral persistence contribute, and screened muscle biopsies for the N-protein. We saw equal amounts in patients and healthy controls (who recovered after COVID). No viral particles were inside cells, so we assume remnants and not active viral particles 6/n

[Rob Wüst @RobWust]

@BraedenCharlton Blocking of capillaries by amyloid-containing deposits (or microclots) could reduced exercise capacity. We found these deposits in muscle tissue, but surprisingly not inside capillaries. They were located in between fibers, were higher in patients, and went up after exercise 5/n

[Rob Wüst @RobWust]

@BraedenCharlton Skeletal muscle mitochondrial function and metabolism were altered in patients with #longcovid, and this worsened after induction of post-exertional malaise (PEM). Intense exercise is not good for patients with long COVID! 4/n