Our new study maps the hyperacute phase of ischemic cardiogenic shock in pigs: rapid loss of forward flow, early vasoconstriction, metabolic disturbance & mitochondrial dysfunction. Opens doors to early & mito‐targeted therapies! 🚀
https://t.co/LpPPLcDc7I
Great work by @PeterCaroeeLind - even small changes in potassium is associated with increased risk of in-hospital cardiac arrest
Potassium Levels and In-Hospital Cardiac Arrest: A Matched... : Critical Care Medicine https://t.co/MqcU28dDGz
Now published in @BasicResCardiol 📑🚀
Infusion with #ketones improves hemodynamics and preserves mitochondrial and contractile function and in ischemic #cardiogenicshock 🐷🫀
https://t.co/7ssNZZAxSQ
🚨NEW: The Trump Administration has destroyed a mural of Dr. Anthony Fauci at the NIH Headquarters. The painting was there to honor his work to combat infectious diseases and inspire other health officials.
RETWEET if you stand with Dr. Fauci against the Trump Administration!
Exciting experimental data from Alexander and Lasse from @AUHCardio presented today at @escardio#ACVC2025 🫀
Ketone body 3-hydroxybutyrate may improve hemodynamics in #pulmonaryembolism
Short chain fatty acid butyrate increases CO in healthy pigs (⬇️)
https://t.co/ObiP7bg5cL
@KrisBergHansen from @AUHCardio presenting data on metabolic profiling as predictor of mortality and neurological outcomes in out-of-hospital cardiac arrest patients at #ACVC2025
Published data below ⬇️⬇️
https://t.co/XM7IawoFnr
Proud to present the hemodynamic effects of lactate infusion in #cardiogenicshock at @escardio#ACVC2025: Increased CO due to increased SV, enhanced ventriculo-arterial coupling and improved mitochondrial function 🫀
Full article published in @Crit_Care
https://t.co/FZ5avitxGf
We recently tested the hemodynamic effects of another monocarboxylate, butyrate, with similar molecular structure and function as #ketone bodies 🫀
@CasperHomilius @MoeslundNiels@GNigopan@OHorsdal@jacob_seefeldt
https://t.co/x0eCTQqTJA
Is #lactate friend or foe?
Proud to share our data on the cardiovascular effects of lactate infusion 🫀 Looks a lot like the effects of #ketone infusion? 🤔
@GNigopan@NikolajRittig@AUHCardio
https://t.co/fu2U9IEzbu
Thrilled to share our new study published in @_JCBFM (https://t.co/9lsDXXoru3)! We show that targeting Na,K-ATPase-dependent Src kinase activation can prevent 🧠 hypoperfusion and exaggerated NVC in a an awake mouse model of familial hemiplegic #migraine.
Here’s a short 🧵
This was a tough one. 40000 abstracts screened. Limited evidence for the use of calcium for Hyperkalaemia
Pharmacological Interventions for the Acute Treatment of Hyperkalaemia: A Systematic Review and Meta-analysis - Resuscitation https://t.co/9bFi2M3MVP
@LarsWAndersen1
In HFrEF patients, exogenous ketone body therapy improves cardiac function. But they have a short half life.
Here we show prolonged ketosis and cardiac benefit with 1,3-butanediol in HFrEF patients🫀❤️🔥
@KrisBergHansen@OHorsdal@GNigopan
https://t.co/Ki91t9ksCj
Happy holidays 🍾
Proud to share our recent publications on the neurohormonal effects of #ketone ester treatment and the cardiovascular effects of the novel ketone compound 1,3-butanediol in #heartfailure@HalvorOG@GNigopan@OHorsdal@NikolajRittig
https://t.co/hlRdNBg5hB
Thrilled to announce that we have received ~2mill EUR from @helse_og_omsorg to conduct the STRONG@HOME trial at 7 sites in 🇳🇴🎉.
Building on #STRONGHF, this trial will test efficacy and safety of rapid uptitration of #GDMT after HF hosp can be performed by digital follow-up 📲