Liuba Dvinskikh

Postdoc in optical microscopy @group_laser @cambridge_uni
Previously @imperialcollege
Also on Bluesky as ld-light

[Liuba Dvinskikh @LD_light_]

We hope this will open up further applications for fast 3D imaging of tissues and complex structures with sub-cellular resolution, using conventional sample mounting techniques. Full details 👉 https://t.co/Okkk29oecm (🧵 6/6)

[Liuba Dvinskikh @LD_light_]

✨ Now out in Biomedical Optics Express: Cleared tissue dual-view oblique plane microscopy 🔬: https://t.co/Okkk29oecm (🧵 1/6).

[Liuba Dvinskikh @LD_light_]

We demonstrate our method on biological samples with a range of RIs, including a whole fly brain 🧠 (imaged in < 3 min⚡) and > 1 cm long mouse bone 🐭🦴 (🧵 5/6).

[FocalPlane @focalplane_jcs]

🔬Our preprint list is now up on FocalPlane. This week we focus on new tools and techniques in imaging. Let us know if we are missing any recent preprints that you've enjoyed reading.
https://t.co/J8JzDOiGFK

[Itai Yanai @ItaiYanai]

Doing good science is 90% finding a science buddy to constantly talk to about the project.

[Laser Analytics Group (Kaminski Lab) @group_laser]

Superresolution microscopy at sub zero temperature: 2 year post doc position available in @group_laser in @cebcambridge and @BAS_News doc to build instruments to study life in the Antarctic. 🔬🥶🐟🧑‍🔬 https://t.co/CnFlx5D8ud

[Liuba Dvinskikh @LD_light_]

Had a great time at #FOM2023 🔬in Porto with others from @ImperialPhysics Biophotonics group, meeting new people and seeing familiar faces offline. Interesting talks and posters, lots of microscopy discussions and sunshine☉.

[biophotonicat @biophotonicat]

Alignment and Characterisation of Remote-Refocusing Systems. (arXiv:2304.00075v1 [physics.optics]) (relevance: 56%) https://t.co/cNb5xilrTC #biophotonics #biomedicaloptics

[Liuba Dvinskikh @LD_light_]

Enjoying day 2 of #FOM2023🔬with lots of light-sheet talks. Visit poster P1-G/3 to learn more about dual-view oblique plane microscopy (dOPM) and its application to high-content imaging of 3D cancer organoid models as part of the @MACH3Cancer CRUK Accelerator.

[Liuba Dvinskikh @LD_light_]

@RunningPhoton @FOMconferences @KavliOxford @OxfordChemistry Raindrops on a puddle in Porto? #sunwhereareyou

[Liuba Dvinskikh @LD_light_]

We hope that visualizing iPSC-CM & adult-CM coupling through fast 3D LSFM imaging of Ca dynamics is a step towards better understanding of iPSC-CM electromechanical integration with native
tissue🫀, and identifying potential sources of arrhythmia in stem cell grafts💓(6/6)

[Liuba Dvinskikh @LD_light_]

Further work from my PhD out in @SciReports : https://t.co/CsBMdjxwZw

With Hugh Sparks, @liliana_brito91 , Ken MacLeod,
@sian_harding, and Chris Dunsby

Many thanks to @ImperialPhysics @impchemistry
@icbcdt @NHLI @EPSRC @TheBHF

A mini-tweetorial (1/6):

[Liuba Dvinskikh @LD_light_]

We also observed maintained electrical coupling in immobilized cells, without mechanotransduction, however further work is necessary to characterize the coupling mechanism.

Video: Orthoslices through adult-CM on iPSC-CM with synchronized spontaneous Ca transients (5/6).

[Liuba Dvinskikh @LD_light_]

2D #LSFM at ∼400 fps enabled spatial mapping of the ms-timescale dyssynchrony of calcium spark and transient dynamics in correlation with the t-tubule structure in ventricular cardiomyocytes. 🫀🔬

(Magenta - CellMask Orange, membrane stain, Green - Fluo-4, Ca indicator) (2/2)

[Liuba Dvinskikh @LD_light_]

Study from my PhD work recently out: https://t.co/xV9GJYzpuL

With Hugh Sparks, Ken MacLeod and Chris Dunsby
(1/2)