Lots of people have known for a while that guardrails for frontier model APIs are very easily jailbroken, quite shallow and impossible to fix. They’re mostly a smokescreen and distraction, in my opinion. We need a different paradigm for AI safety!
We’re launching Claude Corps, a national fellowship program matching people early in their careers with US nonprofits.
We'll teach 1,000 people to use Claude, and pay them to use AI to advance their hosts’ missions.
https://t.co/QI6JmlAdSr
Today I'm publishing a new essay, Policy on the AI Exponential. AI is progressing extremely fast—much faster than the policy process was built to handle. The essay lays out where I think the technology is now, and the action needed to close the gap: https://t.co/Lh6PWae178
Australia’s fertility rate has plummeted.
They’ve hit the lowest rate in history at 1.48 — well below the 2.1 replacement rate.
The average age of mothers was 25 in 1971, and now it’s 32.
This is a human catastrophe.
A single dose of a new cancer drug made a brain tumor almost disappear – in just five days.
Doctors at Massachusetts General Hospital reported “dramatic and rapid” tumor regression in the first patients treated with a next-generation form of CAR T-cell therapy for glioblastoma, one of the most aggressive brain cancers known.
The therapy, called CARv3-TEAM-E, was developed to overcome a major hurdle in treating solid tumors: their ability to hide from the immune system.
The personalized treatment reprograms a patient’s immune cells to attack the tumor, and in one extraordinary case, nearly eliminated the cancer within just five days. This novel therapy is designed to target multiple features of the tumor at once, a strategy that may help overcome the common challenge of treatment resistance in solid tumors like glioblastoma.
Although the tumors eventually returned, the early outcomes were described as unprecedented. One patient saw a 60% reduction in tumor size that lasted for half a year—an impressive result in a cancer known for its aggressiveness.
The trial’s success marks a major step forward for immunotherapy in brain cancer and raises new hopes for long-term control or even a cure. Researchers are now working to refine the treatment and extend its effects, with the ultimate goal of turning a once-terminal diagnosis into a survivable condition.
Today, we are officially launching the Sakana AI RSI Lab in Tokyo to build open-ended, adaptive AI systems that collectively self-improve. I am incredibly proud of our team’s work over the past 2 years, shipping the breakthrough research that laid the foundations for this moment.
Building in Japan provides us with the ultimate design constraint. Just like Japan’s historical dominance in manufacturing was achieved by fundamentally redesigning the factory floor to do more with less, we are focused on compute-efficiency.
We are not building the most compute-hungry self-improvement engine. We are building the most sample-efficient one.
If you are entirely unsatisfied with the brute-force status quo and ready to build the self-improving future in Japan, come join us.
We’re going all in on World Models.
Today we’re launching the 1X World Model Lab.
The bet is simple:
You can’t fine-tune your way to AGI.
And you definitely can’t fine-tune your way to robots that can operate in the physical world.
General-purpose humanoids need models that understand space, motion, objects, causality, affordances, physics, and action before they ever see a specific task.
The frontier is not better VLA wrappers.
The frontier is embodied world models.
The 1X World Model Lab will focus on large-scale embodied world model pretraining: building the most generalizable foundation model for humanoid robots from the ground up.
The next frontier in AI requires scaling:
web-scale media + egocentric human videos + sim + dexterous remote operated robot data + on-policy NEO data → real-world deployment for robot data collection and RL → abundance of data → physical AI
The robot collects data.
The model gets better.
The robot gets better.
Repeat.
To lead this, we brought in one of the best for the mission: @_sam_sinha_ , as Head of World Models.
Sam was a founding research scientist at Luma AI and has been at the frontier of scaling multimodal generative video models his whole career.
If you’re the best in the world at large-scale pretraining, video models, robotics, RL, infra, or data — and you want your models to move atoms, not just pixels — join us.
Send background + evidence of exceptional ability to:
[email protected]
We’re building the model that makes autonomous labor real.
How well do the security community's techniques hold up against AI-enabled cyberattacks?
We examined 832 malicious accounts and mapped their activity onto a longstanding database of tactics and techniques used by threat actors.
Here's what we learned:https://t.co/fgOqJRh2rx
Celebrating the milestone of a massive 150+ million downloads of Gemma 4 with the release of the new Gemma 4 12B model! It's incredibly powerful for such a small model and it’s tiny enough to run locally on a laptop with just 16GB VRAM. Apache 2.0 license - happy building!
When we launched the ARK Venture Fund in September 2022, our goal was clear: democratize access to venture capital and many of the most important innovation platforms evolving today.
Today, the ARK Venture Fund has surpassed $1 billion in assets under management. What stands out to us most is the acceleration in adoption. It took just over two years to reach our first $100 million. The next $900 million followed in roughly 18 months, with the last $500 million coming in only about five months.
In our view, investors increasingly understand that many of the most transformative companies in the world are staying private longer. Public markets alone no longer provide full exposure to disruptive innovation.
Through the ARK Venture Fund, investors can access companies we believe are shaping the future, including SpaceX, OpenAI, Anthropic, Figure AI, Epic Games, and others, at a minimum investment accessible to a much broader audience.
This milestone feels less like a finish line and more like confirmation that innovation is becoming the new asset class.
To our shareholders, advisors, and partners: thank you for your trust and conviction. We believe we are still in the early stages of one of the most profound technological transformations in history.
View ARK Venture Fund holdings: https://t.co/nGkOnPgZPC
Targetted for the Mons Mouton region, this should be further south than any other US payload when it lands.
Blue Moon Mk1 was supposed to be further south, and China's Chang'e 7 will be on the rim of Shackleton.