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@DoctorTro Training to failure twice a week is solid advice. Lean mass drops alongside fat during GLP-1 loss, but the best randomized comparison shows no excess lean share lost, and a DXA scan isn't muscle, strength or function. Long-term, that's still open.
https://t.co/KzQvnc1IqP
@FFT1776 That's the visible failure. The deeper one: across PubMed, compounded GLP-1s have only been given to 94 people in one study, whose authors drew salary support from the wellness chain the participants bought from. That's the study we walked through.
https://t.co/bQZQ2Kfbo9
@investseekers Those numbers are solid; the trials are close too: 13.6% weight loss on the tablet, 14.9% on the injection. But separate trials, not a head-to-head, and oral exposure varies more person to person. We compared what each trial measured.
https://t.co/MtrHSiPiR9
@MohammedAlo The useful distinction is not “muscle panic” versus “no problem.” Trials commonly report lean mass, not muscle quality, strength or function. Absolute lean-mass loss can coexist with a better lean-mass share after larger fat loss.
https://t.co/KzQvnc1IqP
@maxmarchione Animal anecdotes cannot establish human efficacy. Dogs may not know they received a peptide, but outcomes can still reflect natural recovery, concurrent care and observer expectations. BPC-157 still lacks reliable human clinical evidence.
https://t.co/cNCPyeRaJC
@jjh_lifts DXA adds useful context, but it does not show muscle preservation. In the 189-person, 36-week substudy, fat mass fell more than lean mass—yet lean mass still declined. Strength, function and sarcopenia were not measured.
https://t.co/Qmr6tR3itF
@lightsilver323 https://t.co/Yv0jAXt7RQ — Know your status. Build your edge. Expand your access.
The platform is in development. Edge is live today: evidence-led articles on health, performance, relationships, careers and social status.
https://t.co/MTizqig8yh
Do GLP-1 drugs cause disproportionate muscle loss?
Lean mass often falls. Fat usually falls more. But lean mass is not skeletal muscle, strength or function. Direct evidence remains thin.
Read the evidence: https://t.co/KzQvnc1IqP
#GLP1#MuscleHealth
Oral and injected Wegovy use the same molecule. Separate trials do not prove they match.
25 mg oral: -13.6%
2.4 mg weekly injection: -14.9%
No direct obesity head-to-head tested equivalence.
Read the evidence: https://t.co/MtrHSiPiR9
#Semaglutide#GLP1