@Ella_Maru@Anders_S_Hansen Anecdotally, using 4C style plots you can see signal enrichment of CTCF-promoter interactions. (We haven't looked at this in this dataset specific though!)
📣 Excited to share our latest work, in which we set out to reconstitute #3Dgenome folding in vitro to get more insight into the underlying mechanisms. Summary of our surprising findings below! 1/7
https://t.co/AA34QkTXmY
My first trip to the Gothenburg Book Fair was an amazing experience.🙏🏾 The release of the animated tv show based on my book series Karma and Jonar is scheduled for December 4th. It will be available in 11 different languages! I can’t wait.🤩
#illustration#ChildrensBooks
We've been exploring the new #T2T human genome assembly compared to previous versions (our news and views article is out today, link below). Some observations:
(1) Its pretty amazing what the human genome project was able to do in 2004: large-scale gene order is totally conserved
Our paper "Promoting the Genomic Revolution in Africa through the Nigerian 100K Genome Project" is published in @NatureGenet today
The wait for the AFRICAN LARGEST RICH WELL-CHARACTERIZED Genomic data is almost over.
@weare54gene
@AbasiEneobong
https://t.co/QyzZ0szaJW
Excited to share our @biorxivpreprint out of the @LiamHoltLab!
Condensation of LINE-1 is required for retrotransposition
https://t.co/WN9hfELuSO
See this Tweetorial for the bottom line(-1)! 1/5
Congratulations to @JKeithJoung for winning the 2022 Ho-Am Prize in Medicine for his many contributions to advancing the field of genome editing! 👏🍻🎉
https://t.co/RrEK0wcY7I
New @TheLancet
A randomized assessment of 6 different vaccine boosters (3rd shots) after AZ or Pfizer vaccinations: They worked well to boost antibody and cellular immunity, with variability in magnitude of response
https://t.co/8XL4TCOehF
Wow! I am honored to be in the company of amazing #ForbesUnder30 honorees. I could not have made it this far without the support of awesome mentors, peers, and friends. Check out our awesome cohort here: https://t.co/dwQWGe9Rn5
Here is another very exciting preprint, where we presented unfolded chromatin configurations under tension and crowding. We found that the zig-zag fibril structure breaks into nucleosome clutches, resembling those reported by in vivo experiments.
https://t.co/tLrO5IXlA6
Congratulations to @aayushraman, @orouji, @raikunal and team! Their paper on enhancer-defined subtypes of colorectal cancer with therapeutic implications is out in Gut: https://t.co/H91tyAkTax
Excited to share our new method for untangling 3D genome structure in cancer, published @naturemethods. NeoLoopFinder can automatically resolve complex SVs, assemble local genome, reconstruct Hi-C maps, and identify hijacked enhancers for oncogenes.
https://t.co/O5lnVeUsK5