Matthieu Benoit

Research assistant professor at Albert Einstein College of Medicine.
Biophysical studies on molecular motors.

[Matthieu Benoit @matthieuBenoit1]

https://t.co/PD2GeImx2D

Since preprint, the #CryoEM datasets were further processed with #Relion to separate kinesin dimers or coexisting conformations on microtubules. 3 of 20 structures (2.7-3.9 Å) below. @SosaLab4 @SEMC_NYSBC #kinesins #microtubules #biophysics #cellbiology

[Matthieu Benoit @matthieuBenoit1]

Our study to understand how kinesin-8 can have both motility and microtubule depolymerization activities came out!
7 #CryoEM structures @SosaLab4. Data collected @SEMC_NYSBC.
Collaboration with @AllinghamJohn lab, biochem & X-ray structure by Byron Hunter.
https://t.co/wKefPEusva

[Matthieu Benoit @matthieuBenoit1]

Our study to understand how kinesin-8 can have both motility and microtubule depolymerization activities
7 #CryoEM structures @SosaLab4
Data collected @SEMC_NYSBC
Collaboration with @AllinghamJohn lab, biochem & X-ray structure by Byron Hunter
#microtubule
https://t.co/XnHvNKwaqQ

[Michael Cianfrocco @mcianfro]

1/ Excited to share our work on how kinesin binding protein (KIFBP) regulates kinesin! TL;DR: KIFBP remodels the kinesin motor to inhibit microtubule-binding

[Rui Zhang @RuiZhangWUSTL]

We are very excited to share our latest work, the high-resolution cryo-EM structure of the ex vivo cortical #microtubules from human parasite #Toxoplasma gondii. This work is in collaboration with David Sibley lab and @alanbrownhms lab.
https://t.co/lqnOvMT7Zv

[Greg Pintilie @gpintilie]

Fascinating microtubule structures solved by sub-tomogram averaging using EMAN (@sludtke and Muyuan Chen), imaging in @chiulab, segmentation with Segger! Identified tubulin proteins in different arrangements along with other components https://t.co/QtJUG9xWgb

[Rui Zhang @RuiZhangWUSTL]

Another wonderful collaboration with @alanbrownhms and @DutcherLab. Here we put complementary data together to build the complete structure of two distinct radial spokes on doublet microtubule. It was also a great experience to coordinate with the Vale lab for paper submission.

[Matthieu Benoit @matthieuBenoit1]

@DwightRyely @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks!

[Matthieu Benoit @matthieuBenoit1]

18 new #cryoEM structures of the kinesin molecular motor KIF14 reveal its translocation mechanism
@SosaLab4
https://t.co/8PqO24fMsc
Collaboration with Kwok lab. Data collected at @SEMC_NYSBC
#EinsteinMed #MTmotors #kinesins #microtubules #biophysics @cryoEM_Papers #cellbiology

[Matthieu Benoit @matthieuBenoit1]

@electronimus @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks!

[Matthieu Benoit @matthieuBenoit1]

@edward_eng @SosaLab4 @SEMC_NYSBC Thanks @edward_eng! My experience as a user @SEMC_NYSBC is absolutely amazing.

[Matthieu Benoit @matthieuBenoit1]

@ryotaiino @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks!

[Matthieu Benoit @matthieuBenoit1]

@ChuckSindelar @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks Chuck!

[Matthieu Benoit @matthieuBenoit1]

@ArvindQuantum @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks!

[Matthieu Benoit @matthieuBenoit1]

@Rami_Aport @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks!

[Matthieu Benoit @matthieuBenoit1]

@RadoDanev Thanks!

[Matthieu Benoit @matthieuBenoit1]

@RuiZhangWUSTL @SosaLab4 @SEMC_NYSBC @cryoEM_Papers Thanks Rui!!

[Rui Zhang @RuiZhangWUSTL]

First paper from my lab after entering a new field. Great collaboration with @alanbrownhms and @DutcherLab! In this paper we use high-resolution #cryoEM to identify 38 ciliary doublet associated proteins including 33 #microtubule inner proteins (#MIPs) 😎
https://t.co/EIT2PYXPwR

[THERY Manuel @ManuelTHERY]

Here is what molecular motors, kinesins in this example, actually do to microtubules as they walk on them. 😵
Want to know how microtubules can survive in real life ? Have a look at our recent investigation:
https://t.co/nDRCU2U7ZG
@SamReckPeterson @christlet @Lblanchoin

[The Nogales Lab @NogalesLab]

Pre-print on our latest #PRC2 work, spearheaded by @vignesh_k757 and supported by many collaborators: Curtis Beck, @poepsel_lab, @malamenteau, Jennifer Kosmatka, Dan Toso at the #BACEM facility, and Marco Faini in the Aebersold Lab in Zurich. #cryoEM
https://t.co/Aumfmwqh10