JustAnotherMedic

nemo

[JustAnotherMedic @MedicAnother]

http:// nodes both sides of diaphragm tent/uploads/2015/05/hodgkin-lymphoma-pathogenesis-and-clinical-findings.jpg
#haematology #hodgkins-1832-classical and #nodularLymphocytePredominant (CD20+ CD15/30 neg)-
#stage1 2contig ng
#stage2 node SS of diaphragm
#stage2 nodes both side

[JustAnotherMedic @MedicAnother]

#lymphoma
From lymph, from Latin lympha (“water”) and -oma (“disease, morbidity”).

B symptoms are so called because Ann Arbor staging of lymphomas includes both a number (I–IV) and a letter (A or B). "A" indicates the absence of systemic symptoms, "B" indicates their presence.

[JustAnotherMedic @MedicAnother]

https://t.co/AhuTMFDThh
#hodgkinsLymphoma #matureBcells #reedSternberg #Bsymptoms neck nodes 75% -- #ebv in 30%

[JustAnotherMedic @MedicAnother]

https://t.co/tXhG6a3FEV
#ECG
“Pre-excitation”: #shortPR, slurring #deltaWave into wide QRS. #bundleofKent
Rate:Normal with episodes of #SVT
PRinterval: Short >0.12s
#QRSBroad >0.12s (>3 small sqs)
Accessory abnormal conduction pathways “Bundle of Kent”) formed during #cardiacDev

[Kevin Kuan @kkuanMD]

My wife managed to find this book for me. It is arguably the oldest book about forensic science (published 1247). Some of the techniques employed are interesting.😆 #PathTwitter #forensics #pathology @WKemp_MT_FPDoc @yokoda_md @DrAngelaBaldwin @drjudymelinek @TristanRutland7

[JustAnotherMedic @MedicAnother]

#physiology #micturition
1. #M3 Ach stretch R activated
2. #Parasympatheticpelvicnerve fibres carry signals via S2&S3 spinal segments -
3. #REFLEX from S2&3 SC to parasymp gang excited #detrusor
4. External urethralSphincter excited by S4 #pudendalN.
5. #pons #voluntaryControl

[JustAnotherMedic @MedicAnother]

#cardio #ECG of #LVH.  

A. #VoltageCriteria: #Sokolow-Lyon index: [S in V1 or V2] + [R in V5 or V6] (whichever is larger) ≥ 35 mm (≥ 7 large squares).

B.  #LeftVentricularStrain --- #TWaveInversion in lateral leads: V5-6, I and aVL.

C. #LeftAxisDeviation

[JustAnotherMedic @MedicAnother]

This system where consultants expected to make decisions on patients without a deep information search is bad for doctors and bad for patients. It's a horrible system that minimises dignity and is Kafka trial-esque. #reformNeeded

[JustAnotherMedic @MedicAnother]

https://t.co/s0u2oKO1JM
#더보이즈 #pharmacology #loopDiurectics inhibit #sodiumPotassiumChlorideCotransporter 1(na+):1(k+):2(cl-) within the #thickAscendingLimb usually reabsorbs 25% of the filtrate sodium load.

[JustAnotherMedic @MedicAnother]

https://t.co/o53X9QO4WW
i#nterestingMedicine #trigeminalReflex

[JustAnotherMedic @MedicAnother]

#anticholinergics #pharmacology #top100 #atropine -
1. at LOW doses inhibits M1 (vagal) ---> BRADYCARDIA ♤can also use glycopyyronium♤
2. At HIGH doses blockade of M2 receptors ---> TACHYCARDIA
Adv-♤raised intraocular pressure CAglaucoma♤tachy♤retention♤dryMouth♤blurred

[JustAnotherMedic @MedicAnother]

https://t.co/aeXP73sqDZ
#geriatrics
#Pressureulcers -- grade1 - 4 or ungradable -- grade 1 now have subdivision/ clarifyication re possible deep tissue injury https://t.co/TWj8RvEZvw

[JustAnotherMedic @MedicAnother]

https://t.co/HFiqcknsnp
#cardiology #pharmacology
#SinoAtrialNode - pacemaker
1. Funny channels (ish)
2. #Sympathetic Adrenaline at Beta adrenergic receptors inc HR (#BBlockers inhibit)
3. #parasympathetic Ach at Cholinergic recent slow SA - (anticholinergics - #Atropine incHR)

[JustAnotherMedic @MedicAnother]

https://t.co/masTiFshnu
#pharmacology #top100 #adenosine #SVT

[JustAnotherMedic @MedicAnother]

https://t.co/peaS0YlpoW
Giants of #Geriatrics
#Immobility
#instability
#iatrogenesis
#incontinence
#IntellectualImpairment
And...
Psychological/sleep/medication concordance+appropriateness/Visual/hearing/dentition/ appetite/swallowing/pressure sores/ PAIN/footcare #beHolistic

[JustAnotherMedic @MedicAnother]

https://t.co/vkBMq9POFP
#neurology
#Encephalomalacia the softening or loss of brain tissue after cerebral infarction, cerebral ischemia, infection, craniocerebral trauma, or other injury. blurred cortical margins and decreased consistency of brain tissue after infarction

[JustAnotherMedic @MedicAnother]

https://t.co/zcfiST3hm1
#pharmacology
#ParacetamolOD
#NAcetylcysteine is for the treatment of paracetamol OD. Source of cysteine for glutathione synthesis and possibly to form an adduct directly with the toxic metabolite of N-acetyl-p-benzoquinoneimine. https://t.co/RdDLoPrfGc

[JustAnotherMedic @MedicAnother]

#Pharmacology of #Adenosine Receptors: The State of the Art | @PhysiologicalReviews https://t.co/VTnZ97Uu4S
I: SVT Adv: bradycardia, asystole, 'impending doom' MOA-- 'retaliatory metabolite'

[JustAnotherMedic @MedicAnother]

https://t.co/wcOZ7autGu
#pharmacology
#AceInhibitors
Monitoring UEs -every 2 weeks every 3 months -then at least every 6 months and if person acutely unwell
Titrate up does every 2 weels
CI - avoid in pregnancy especially 2/3 trimester
Lithium toxicity; levodopa inc hypotension

[JustAnotherMedic @MedicAnother]

https://t.co/kK38BlM0r3
#pharmacology #aceinhibitors
#Angiotensin 1 --X---> angiotensin 2
Build up of bradykinin causes vasodilation/inc vascular permeability and angioedema
Interactions- lithium, potassium increasing diuretics