🇪🇺🇩🇰🇺🇦Michael Christiansen 🇺🇦

Professor, chief physician. #genomics, #cardiac #psychiatry, #fetal #publichealth Statens Serum Institut & Copenhagen University. Tweets are mine and only mine.

[Dr Alexey Kulikov @KulikovUNIATF]

Denmark 🇩���� becomes first country in the European Union to eliminate mother-to-child transmission of #HIV and syphilis.

The World Health Organization @WHO has certified #Denmark for the elimination of mother-to-child transmission of HIV and #syphilis, recognizing the country's sustained commitment to ensuring every child is born free of these infections.

“The elimination of mother-to-child transmission of HIV and syphilis marks a major public health achievement for Denmark,” said @DrTedros Adhanom Ghebreyesus, WHO Director-General.

“This milestone demonstrates that with strong political commitment and consistent investment in primary care and integrated maternal and child health services, countries can protect every pregnant woman and newborn from these diseases.”

https://t.co/JoAmh3WKiS

[Nature Metabolism @NatMetabolism]

#Throwback

COMMENT |

@ClemmensenC, @Z_GerhartHines, @Thue_Schwartz, @JuleenRZierath, @Kei__Sakamoto

Shaping the future of cardiometabolic innovation: advances and opportunities

https://t.co/SZWrOUrdKA

[The Parliament Magazine @Parlimag]

Did Europe’s rare disease incentives spark real breakthroughs, and can the next rules keep momentum going? As the EU updates how it defines “unmet need”, the choices now will shape where research investment flows next, write @PTCBio. Partner content

[Sara Moscatelli @saramoscatelli7]

🚸 New AHA Statement: Let kids with cardiomyopathy MOVE! ❤️‍🔥
For years, children with cardiomyopathies were often told to avoid physical activity due to fear of sudden cardiac death ⚠️

👉 But new evidence is changing the paradigm:
✅ Physical activity is essential for cardiovascular, emotional & social health
✅ Risk during exercise may be lower than previously thought in selected patients
✅ Exercise can even support functional improvement & reverse remodeling
✅ Sedentary lifestyle = higher risk of obesity, hypertension & poor QoL

💡 The key message:
➡️ Individualised risk stratification + shared decision-making = safe participation for most patients

⚖️ Not “restrict vs allow” — but tailored prescriptions based on phenotype, genotype & patient goals

👨‍👩‍👧‍👦 Let’s move from fear to empowerment

📄 Read the full statement here: DOI: 10.1161/CIR.0000000000001431

#Cardiology #PediatricCardiology #Cardiomyopathy #AHA #SportsCardiology #ExerciseIsMedicine #SharedDecisionMaking #CMR #Genetics #HeartHealth 💙

[Sara Moscatelli @saramoscatelli7]

⚡ Brugada syndrome is not just a sodium channel disease.

For years, we simplified Brugada as:
👉 SCN5A
👉 sodium current
👉 channelopathy
But here’s the problem:
👉 This explains only 20–30% of patients
🧠 So what about the rest?
This paper pushes the field forward:
👉 Brugada = a multi-layer disease
🔬 New insight: proteomics
Using Mendelian randomization across large cohorts,
they identify novel protein pathways linked to BrS:
• Cytoskeletal regulation
• Stress-response signaling
• Extracellular matrix remodeling
➡️ Not random findings
➡️ A coherent biological network

💥 Key players:
• MMP1 → fibrosis / structural substrate
• HSPB1 → protein folding / stress response
• MAPKAPK2 → inflammation + signaling
• PDLIM4 → cytoskeletal organization
🔥 Translation:
👉 The problem is not only the ion channel
👉 It’s the environment where the channel lives
⚡ This explains what we already see clinically:
• Epicardial substrate
• Fibrosis in RVOT
• Inflammatory signals
• Success of substrate ablation
👉 Hard to reconcile with a “pure channelopathy”
🧬 New concept:
👉 Structural + molecular dysfunction
→ leads to an “acquired channelopathy”
Even normal channels
can behave abnormally in a diseased substrate
⚠️ And this changes everything:
• Risk stratification
• Biomarkers (plasma proteins?)
• Patient selection for ablation
• Future targeted therapies
🎯 Take-home message
Brugada is evolving from:
⚡ channel disease
➡️
🫀 substrate-based cardiomyopathy
💬 Are we ready to stop calling Brugada a “pure channelopathy”?
#Cardiology #BrugadaSyndrome #Arrhythmia
#Genetics #PrecisionMedicine #EPeeps
#CardioTwitter ⚡🫀

https://t.co/qjxHJAvXaV

[Jan E. Jørgensen @JanEJoergensen]

Så kom man i @politiken

[Eric Topol @EricTopol]

The turning point for rare diseases, which affect >300 million people around the world.
A call to get rid of its many structural obstacles, to consider it as molecular surgery unlike drug treatments
gift link:
https://t.co/DQ0OZ9tXXc

[🇪🇺🇩🇰🇺🇦Michael Christiansen 🇺🇦 @MIC_CPH]

@EricTopol @NextMedHealth This must also be the turning point for neonatal screening for rare genetic disorders. Screening has previously not been performed due to lack of treatment…the scene seems set for population genomics as a major health improvement.

[Petra Blankwaard @indigonl]

Wow, this is wonderful!! 🚑🇺🇦

Facebook post Falck Denmark 🇩🇰

Last Friday, this ambulance convoy began its journey from Denmark to the front lines in Ukraine 🚑🫶🇺🇦

We’re proud to share that the first 10 out of 20 ambulances, donated by Falck, have now been delivered to support emergency rescue operations. The vehicles will become part of the local emergency services and are ready to make a real difference ❤️‍🩹

The initiative is led by Repower, which supports Ukrainian medical units and healthcare professionals including through rehabilitation camps in Denmark that help them continue their vital work.

A huge thank you to Repower for managing the project and ensuring the ambulances were delivered directly to brigades in the field 🙏

We also want to give a big shout-out to the Danish companies that donated essential medical equipment for life-saving treatment, and to the volunteers who drove the ambulances all the way to Ukraine 🫶

At Falck, we’re proud to contribute to this important cause and to help turn care into action ❤️

#WeTurnCareIntoAction

[Camus @newstart_2024]

Richard Feynman’s savage takedown of pseudo-science still burns in 2026:

“Social science is an example of a science which is not a science. They follow the forms… but they don’t get any laws. They haven’t found out anything.”

He goes harder:

Experts who “sit at a typewriter and make up” claims — “organic food is better,” “this diet cures everything” — as if it’s settled science, when no rigorous experiments or checks have been done.

Feynman:

“I know what it means to really know something.
How careful you have to be. How easy it is to fool yourself.
I see how they get their information… and I can’t believe that they know.”

The Nobel physicist calls it straight: most of what passes for “expert” opinion is noise dressed up as knowledge.

In an age drowning in TikTok “science,” influencers, and clickbait studies — Feynman’s 1:52 rant feels more relevant than ever.

Who’s the biggest pseudo-expert that grinds your gears right now?

Clip is timeless fire — watch it and feel the clarity.

[Elisa Mosini 🇪🇺🇮🇹 @MosiniElisa]

One thing must be acknowledged about France:
It has always emphasized the importance of Europe’s strategic independence from the US.
Europe has often overlooked this warning.
If Europe can aspire to autonomy today, credit must be given to Paris for keeping this vision alive. 🇫🇷🇪🇺

[Ian Weissman, DO @DrIanWeissman]

“Having comprehensive criteria matters because endometriosis is not a one-dimensional disease. It presents differently from patient to patient, can affect multiple organ systems, and often overlaps with other pain symptoms.”
https://t.co/jJDmIKObrd

[Native American @_nativeamerica]

My daughter poured her heart into this school project . A bit of support would mean everything to her.

[American Heart Association @American_Heart]

Making the switch from pediatric to adult congenital heart disease (ACHD) care is a critical step for teens with heart disease. Start the conversation early. Stay connected. Stay healthy.

[Ashley @Ashley_22ky]

They said she couldn’t raise me.
They said it would be “too hard.”
They were wrong.
My mom, Grace, raised me by herself while living with Down syndrome. When I was born, people doubted her. They warned her. They questioned her ability

[Mark Wright @markeology]

My angelic, autistic 12 year old daughter Annika drew this pencil and asked me to share it with you. She gets giddy when her content does better than mine, which makes me happy.

Please share it far and wide to keep her fire for art going. We've just barely gotten it rekindled.

[Søren Pind @sorenpind]

❤️🇫🇷🇩🇰

[Monica Lylloff @LylloffMonica]

“Folk tror, at alting er fantastisk i vores velfærdssamfund, fordi vi betaler skat. Det er der også områder, hvor det er, men handicapområdet er ikke ét af dem.”
Jeg ser frem til, at det bliver en del af valgkampen!
#dkpol #enmillionstemmer #dkmedier

https://t.co/0uuvp95nfP

[Andreas Andersen @apandersen]

Man er godt i gang med at udrydde livmoderhalskræft takket være HPV vaccinen. Det var godt vi fik indført den i Danmark og det meste af verden