🚨New Paper: "Seven Years of 700 Cholesterol Without Coronary Atherosclerosis: A Lean Mass Hyper-Responder Case Report"
Link: https://t.co/5VnRpZlFdR
For the past 7 years, I’ve been running what is essentially a natural experiment in cholesterol and heart health.
During that time, I’ve largely lived with:
👉Total cholesterol around 700 mg/dl
👉LDL cholesterol between 500–600 mg/dL
I recently underwent advanced coronary CT angiography imaging with AI-guided analysis. This is not a CAC. It measures all plaque (soft + calcified), with expert interpretation and AI-guided analysis capable of quantifying plaque down to the cubic millimeter (mm3).
Now, to address the obvious question:
Am I too young for plaque?
In brief: No.
The clearest comparison is individuals with homozygous familial hypercholesterolemia, who often have similarly extreme LDL/ApoB levels and can develop advanced plaque as toddlers, and even heart attacks as early as age 8.
Also, nutrition influencers in their 30s have publicly shared quantified plaque scores from these same imaging technologies. In one recent case, a plant-based influencer in his thirties was found to have 61.3 mm³ of plaque despite having far lower lifetime LDL exposure. (He can identify himself if he so chooses.)
My case also isn’t a one-off.
There are many individuals like me, including older individuals with similar LDL-C and ApoB without any plaque.
The difference is that I’m an unusually well-characterized subject, with extensive metabolic data and health markers tracked over time. You can learn more at the newsletter or open-access paper, linked above.
The science of heart health is not settled. And cholesterol is not a simple story.
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@Anthony_B_36@realDaveFeldman@JeffryGerberMD Nothing has happened to me, I started a manufacturing facility in Arizona and have been busy getting things up to snuff there but will be back to content creation soon. Thanks for your concern though!
When The “Cholesterol Drop” Misses the Mark
(Links in 6/7 and 7/7)
1/7) Can we assume that how much LDL drops tells us how much cardiovascular risk is reduced?
A new meta-analysis in the European Heart Journal says, “No.”
In fact, it suggests the link between LDL-C reduction and actual cardiovascular outcomes is incredibly weak.
So, have we built a multi-billion-dollar industry on the assumption that hot chocolate equals real illness?
Let’s unpack that…
cc @realDaveFeldman@AdrianSotoMota@ApoDudz@DrEricRodgers@LDLSkeptic@AKoutnik@janellison@bschermd
Getting our meals, bedtime, and workouts at the same time every day have a surprising impact on health. Our hormones synchronize to routine and our health benefits from it! Get ontime today.
@MikeMutzel
Excuse me for a little bit longer, Internet. Just did a longform podcast with @MikeMutzel , and we’re gonna catch a steak.
Let me know what I missed while I was away. 😂
🚨🚨🚨BREAKING🚨🚨🚨
#LMHRstudy / KETO-CTA published!
100 lean, metabolically healthy #keto:
🔥 No association of #ApoB with #plaque ↗️
🔥 No association of #LDL#cholesterol with #plaque ↗️
🫀What is association? Existing plaque
Read and share 👇👇👇
https://t.co/JkbH2vTB44
VERY URGENT: Top Yale scientists have found of T-cell exhaustion and prolonged spike protein production in some COVID vaccine recipients - with spike levels INCREASING over time.
This is the study I wrote about in December. The preprint is out. It’s very, very worrisome.
@DrNadolsky Yeah statin researcher is unequivocally positive and will extend you life by 3 whole days if you take them for ~6 years. Sign me up! https://t.co/QZ0olT9c5H
I don't understand the New York times. Instead of debunking a straw man, why not ask the question: Why does the US have so many more childhood vaccines than many European nations? That's an interesting question that a lot of people are curious about.
Happy Thanksgiving — three years ago Dr. Fauci said if someone in your family hadn’t gotten the worthless covid “vaccine” you should ban them from Thanksgiving. Never forgot what they did to us. Fauci belongs in prison for the rest of his life: