Drug Discovery Research Lab KCL

A research group at the School of Cancer and Pharmaceutical Science, King's College London with main focus on drug discovery research.

[King's Faculty of Life Sciences & Medicine @kingsmedicine]

Candida auris is a dangerous fungal pathogen that has become a global health concern

Scientists from King's have developed a new class of antifungal compounds that could offer a powerful weapon against it

https://t.co/iWboeLBFOw

[Prof Miraz Rahman @MirazRahman]

Excited to share a new class of azole antifungals from our group that are effective against multidrug-resistant Candida auris. These efflux-resistant molecules exhibit broad-spectrum activity and are advancing towards preclinical development. Supported by @UKHSA and @NIAIDNews

[King's Faculty of Life Sciences & Medicine @kingsmedicine]

@MirazRahman, Professor of Medicinal Chemistry, has been elected as an Expatriate Fellow of the Bangladesh Academy of Sciences (BAS)

This was for his significant contributions to scientific research. He is the first British Bangladeshi scientist to receive this fellowship 👏

[Prof Miraz Rahman @MirazRahman]

As a British Bangladeshi academic, it is a great honour and privilege to be recognised by the Bangladesh Academy of Sciences (BAS) as an Expatriate Fellow. I look forward to working with Bangladesh Academy of Sciences (BAS) to help advance scientific research in Bangladesh.

[Drug Discovery Research Lab KCL @MRahmanLab]

Our new @rsc_medchem paper led by Paolo Andriollo describes a new class of antibody drug conjugate payload that, in a pancreatic cancer model, drives complete tumour regression for 60 days after a single 2 mg/kg dose - outperforming 10 mg/kg Enhertu.

https://t.co/ntJP3NLcAC

[Prof Miraz Rahman @MirazRahman]

This grant from @lifearc1 gives us the opportunity to develop our new efflux resistant antibiotics for treating infections associated with Cystic Fibrosis. It’s a joint project between @KingsCollegeLon and @HealthcareUKHSA.

[Drug Discovery Research Lab KCL @MRahmanLab]

Our group PI @MirazRahman recently sat down with Nature to discuss the role artificial intelligence (AI) can play in transforming drug discovery and development. The article featuring his opinion has been published today, and you can read it here https://t.co/x2rDKVoJpA.

[Drug Discovery Research Lab KCL @MRahmanLab]

New collaborative paper from @MRahmanLab @KCLcancer_pharm with Professor Ramon Vilar @imperialcollege.

Discovery of Phototoxic Metal Complexes with Antibacterial Properties via a Combinatorial Approach | Inorganic Chemistry https://t.co/r3fvDSRiwS

[King's Faculty of Life Sciences & Medicine @kingsmedicine]

Prof @MirazRahman has been awarded a grant by @lifearc1 to develop effective antibiotics for people with cystic fibrosis

The drugs will target a pathogen that causes chronic lung infections in people with the condition

Read more ⤵️

https://t.co/eTfdoQSbdt

[Drug Discovery Research Lab KCL @MRahmanLab]

New collaborative paper from @MRahmanLab @KCLcancer_pharm with Professor Ramon Vilar @imperialcollege.

Discovery of Phototoxic Metal Complexes with Antibacterial Properties via a Combinatorial Approach | Inorganic Chemistry https://t.co/r3fvDSRiwS

[Drug Discovery Research Lab KCL @MRahmanLab]

Our group PI @MirazRahman recently sat down with Nature to discuss the role artificial intelligence (AI) can play in transforming drug discovery and development. The article featuring his opinion has been published today, and you can read it here https://t.co/x2rDKVoJpA.

[Drug Discovery Research Lab KCL @MRahmanLab]

New paper from the group in collaboration with @UKHSA @HealthcareUKHSA .
C7-Substituted Quinolines as Potent Inhibitors of AdeG Efflux Pumps in Acinetobacter baumannii | ACS Infectious Diseases https://t.co/BZyUNil60e

[Prof Miraz Rahman @MirazRahman]

We enjoyed ⁦@MRahmanLab⁩ quarterly Potluck lunch today. Food from 12 different cuisines. Mohammad won with his Afghan cuisine while Paolo was the runner up with his Italian food. Everyone cooked some supper yummy food.

[Prof Miraz Rahman @MirazRahman]

It’s that time of the year to enjoy a meal together and reflect on the achievements and activities of 2024. ⁦@MRahmanLab⁩ members enjoyed their Christmas lunch at Kachori restaurant on Monday. We had a wonderful time together!!

[Drug Discovery Research Lab KCL @MRahmanLab]

Hear from our group lead @MirazRahman about the threat posed by AMR, current research and what needs to happen across govt and industry to tackle this urgently.

[King's Faculty of Life Sciences & Medicine @kingsmedicine]

Antimicrobial resistance is one of the most serious health threats facing humanity

For World AMR Awareness Week, hear from @MirazRahman about:

➡️ The threat
➡️ Promising research
➡️ What needs to happen across govt and industry

[Prof Miraz Rahman @MirazRahman]

We are hosting Professor David Nutt from ⁦@imperialcollege⁩ as part of ⁦@KCLcancer_pharm⁩ IPS seminar series today. David is giving an intriguing talk on the use of psychedelics as future treatments of brain disorders. Fascinating insights on psychedelics!!!

[Prof Miraz Rahman @MirazRahman]

Poster presentation at large academic conferences. 😂

[Prof Miraz Rahman @MirazRahman]

Congratulations to the newest PhD graduate from ⁦@MRahmanLab⁩ Dr Peiqin Jin who led a project on NFkB targeting PROTACss as cancer therapy, co-supervised by ⁦@ChrisPepper64⁩ and ⁦@davidthurston8⁩. Thanks to ⁦@SiFTW⁩ and ⁦@rafalconer1⁩ for examining.

[Prof Miraz Rahman @MirazRahman]

We had a great World Pharmacists Day talk today hosted @KCLcancer_pharm @KCL_Pharmacy by @MagsWatson1 from @UniStrathclyde . Mags talked about ‘The medicine-related needs of older people with sensory impairment’. One of the best talks of the IPS Seminar Series.

[Drug Discovery Research Lab KCL @MRahmanLab]

New pre-print from the group in collaboration with @HealthcareUKHSA. We report new generation modified azole antifungals against multidrug-resistant Candida auris | ChemRxiv - https://t.co/5mBByzImrr