MultiPark at LundU

MultiPark is a translational programme ranging from experimental pre-clinical research to studies on the life situation of patients with #neurodegeneration.

[MultiPark at LundU @MultiparkL]

Important Update from MultiPark!

We want to inform you that MultiPark will no longer be active at X. You can continue to follow our latest research, news, and updates on LinkedIn 👉 https://t.co/Q9dUn35Fn9

Thank you for your support, and we look forward to staying in touch!

[Nano Letters @NanoLetters]

PEDOT is going one-dimensional! Lithography-free conductive polymer nanowires were interfaced with both algae and human blood stem cells paving the way for 1D organic bioelectronics. @lunduniversity @nanolund @MultiparkL @HjortsX @OlssonRoger

https://t.co/e75mhg8dgj

[BioFINDER @biofinder_study]

A new The Swedish BioFINDER study paper in collaboration with WRAP has been published in @Brain1878 !
https://t.co/ZKQIP5dq4h
Find our key findings 👇

[MultiPark at LundU @MultiparkL]

"In this study we identify the glymphatic system as a new mechanism contributing to the well-established link between cardiovascular pathologies and neurodegeneration" says Marios Kritsilis, lead author of the project.

Read more about their findings 👉 https://t.co/yNAGu3nhc2

[MultiPark at LundU @MultiparkL]

The glymphatic system, specialized in clearing waste from the brain, is linked to various neurodegenerative diseases. However, the impact of heart failure on the glymphatic system's function remains poorly understood.

[MultiPark at LundU @MultiparkL]

To address this, @Iben_Lundgaard and collaborators explored how myocardial infarction in mice impacted their glymphatic function.

[MultiPark at LundU @MultiparkL]

Congratulations Gemma!

[Gemma Salvadó @gesalbla]

Such an honour to receive the young investigator award from my favourite conference.
Especially when shared with these amazing researchers!
#HAI2025

[Patrik Brundin MD PhD @BrundinPatrik]

Great review on #stemcell therapies from @Kirkeby_Lab who is affiliated with @Lund_Stem and @MultiparkL at @medfak_LU @lunduniversity

[MultiPark at LundU @MultiparkL]

This work highlights both the potential and the challenges of using DTI in glymphatic research, paving the way for improved techniques to study brain health.

Read more about their findings here 👉 https://t.co/Z0PRqY7Swa

Lead author: Charalampos Georgiopoulos

[MultiPark at LundU @MultiparkL]

The glymphatic system, a specialized waste-clearing network in the brain, plays a role similar to the lymphatic system in the rest of the body. Changes in this crucial system have been linked to neurodegenerative diseases such as Parkinson's and Alzheimer's.

[MultiPark at LundU @MultiparkL]

However, a known limitation of DTI arises when nerve fibers cross—an issue affecting about 90% of the brain's white matter. In their study, the researchers demonstrated how fiber crossing impacts DTI measurements of the perivascular space and the assessment of glymphatic flow.

[Daniella Rylander Ottosson @Ottossonlab]

Happy and honoured to have been awarded a STIAS: Stellenbosch Institute for Advanced Study fellowship for 2025!

Look forward to spend the autumn in South Africa 🇿🇦!

https://t.co/IVAIjLVM87

@lunduniversity @MultiparkL @Lund_Stem @medfak_LU @Ottossonlab

[MultiPark at LundU @MultiparkL]

Recent research highlights corticotropin-releasing hormone (CRH) as a promising biomarker candidate for PS. @OskarHansson9 and collaborators investigated this link, read about their results here 👉 https://t.co/jNi6m5z1jR

Lead authors: @atulkumar1301 and Bárbara Fernandes Gomes

[MultiPark at LundU @MultiparkL]

Biomarkers have transformed Alzheimer's disease diagnosis, and a similar breakthrough is needed for Parkinson's disease and related disorders, known as Parkinsonian syndromes (PS).

[Daniella Rylander Ottosson @Ottossonlab]

Check out the latest reportage from KAW on our reprogramming project!👩‍🔬🧠 @Lund_Stem @MultiparkL @lunduniversity @WISSummit

[Daniella Rylander Ottosson @Ottossonlab]

Happy to share our latest preprint on glia reprogramming to human parvalbumin interneurons! @Lund_Stem @MultiparkL @CellRepJrnl @biorxiv_neursci @Ottossonlab @ParmarLab @NanoLund @lunduniversity

[Lluís Camprubí Ferrer @lluis_camprubi]

The episode I've been most excited about is here. I had the honor to chat with Prof. Bart de Strooper, one of the most brilliant minds researching Alzheimer's today. What an absolute masterclass it was. Listen to it, you won't regret it. @MultiparkL
https://t.co/Ki9W6gdnjn

[MultiPark at LundU @MultiparkL]

#Parkinson #genetics #GBA1 #neurodegeneration #neuroscience #LundUniversity

[MultiPark at LundU @MultiparkL]

Genetic risk factors can vary between populations. The T369M variant in the GBA1 gene has been linked to an 80% increased risk of Parkinson's disease. However, recent findings suggest this association might not apply to the Swedish population.