Dr. Nasreen S. Basoudan 🧠🔍📚🖋️

Consultant Clinical Neuropsychologist | Asst Professor | Ageing | Neurodegenerative Diseases | Visual Attention | Sleep | @kauhospital @kauedu_sa @swanseauni

[Nicholas Fabiano, MD @NTFabiano]

The brain continues to make new neurons throughout life.

It is never too late to learn a new skill.

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

Perhaps one of the brain's greatest gifts is not avoiding the wrong turn, but learning how to adapt after it.

Just as a navigation system recalculates the route, the brain can reorganize, learn, and discover new pathways.

Sometimes, re-routing is not failure; it's neuroplasticity reminding us that growth often begins where the original plan ends 🧠���

#Neuroplasticity #Neuropsychology #BrainHealth #Neuroscience #GrowthMindset

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

لا تُقلّل من أثر حضورك في حياة الآخرين ..
فقد تكون كلمةٌ خرجت منك بعفوية .. أو موقفٌ ظننته عابرا … أو دعوةٌ دعوت بها بصدق .. سببا في أن ينهض قلبٌ كان يوشك أن ينكسر .. أو أن تتغيّر حياةٌ لم تعرف يوما أنك كنت جزءا من تحولها ..
لسنا نرى دائما امتداد أثرنا .. لكننا نملك أن نختار أن يكون أثرا طيبا .
فازرع الخير حيثما كنت .. وأحسن القول .. وأخلص النية .. فما كان لله يبقى .. وما زُرع في القلوب بإخلاص .. لا يضيع وإن غاب عن أعين الناس ..

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

ليست كل الأعراض النفسية ... نفسية المنشأ …

عندما تكون الأعراض غير نمطية … أو سريعة التطور … أو مقاومة للعلاج … ينبغي أن يتجاوز التفكير حدود التشخيص النفسي التقليدي … وأن يشمل الأسباب العصبية والمناعية أيضا …

ففي الحالات التي يظل فيها الاشتباه السريري قائما … لا يستبعد سلبية فحص الدم بعض الحالات … مثل التهاب الدماغ المناعي الذاتي … وقد يكون فحص السائل النخاعي (CSF) مفتاح التشخيص …

فالتشخيص المبكر لا يغيّر الخطة العلاجية فحسب ... بل قد يغير مسار حياة المريض بالكامل …

[Journals of The American Psychiatric Association @APAPubJournals]

Seronegative, cerebrospinal fluid (CSF)–positive N-methyl-D-aspartate encephalitis cases are often associated with comorbid central nervous system disorders or other antineuronal antibodies. Atypical psychiatric symptoms or neurological decline of a psychiatric patient should prompt CSF testing. #JNCN @anpadirect https://t.co/pO8HtCMFs3

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

One of the most exciting shifts in modern psychiatry.

The question is no longer .… Where should we stimulate? But which brain network should we target?

Connectivity-guided interventions may redefine how we treat treatment-resistant depression and perhaps many other neuropsychiatric disorders.

#Neuropsychology #Neuroimaging #PrecisionPsychiatry #BrainNetworks #TMS #DepressionResearch

[JAMA Psychiatry @JAMAPsych]

Individualized, connectivity-based targeting of accelerated transcranial magnetic stimulation produced significantly greater antidepressant effects than scalp-based targeting in adults with treatment-resistant #Depression.

https://t.co/mHdQIS4NVG

[Nicholas Fabiano, MD @NTFabiano]

People who feel younger often have brains that are actually biologically younger.

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

يختبر الله يقين عبده ... لا ليُثقله … بل ليُعلّمه أن النجاة ليست فيما يراه … بل فيما يدبّره الله له …

قد تتأخر أمنية … ويُغلق باب … ويطول انتظار ... حتى يهدأ القلب من التعلّق بكل شيء … ولا يبقى فيه إلا التعلّق بالله …

وحين يكتمل اليقين ... يدرك الإنسان أن كل ما ظنه تأخيرا … كان في الحقيقة أعظم صور الرحمة …

﴿وَمَن يَتَوَكَّلْ عَلَى اللَّهِ فَهُوَ حَسْبُهُ﴾ 🤍

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

في كل مرة يظن الإنسان أنه اقترب من فهم العالم … يظهر سؤال جديد يذكره بأن المعرفة ليست محطة وصول ... بل رحلة لا تنتهي …

ولهذا … لا يقاس التقدم العلمي بحجم ما نعرفه … بل بقدرتنا على اكتشاف حدود ما لا نعرفه …

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

Every thought ...
Every memory ...
Every skill ...

Emerges from billions of neurons continuously building, strengthening, and reshaping their connections.

The brain's remarkable power lies not simply in the number of its neurons, but in the extraordinary architecture of the networks they create.

#Neuroscience #Neuroplasticity #BrainHealth #ClinicalNeuropsychology #Synapse

[Slava Bobrov @slava__bobrov]

Brain cells are making connections. Networking in action:
#neuroscience

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

We often think of sleep as a period of rest.
The brain tells a different story.
During deep sleep, some of its most essential restorative and clearance processes become more active, not despite the loss of consciousness, but because of it.
Perhaps sleep is not simply a pause from brain function.
Perhaps it is when some of the brain's most important work begins 🧠✨
#Neuroscience #Sleep #BrainHealth #ClinicalNeuropsychology

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

لسنا نحزن لأن الزمن يمضي ...
بل لأننا نخلط بين مرور الزمن وانتهاء الفرص …
وهما أمران لا علاقة لأحدهما بالآخر …

فالوقت لا يعد الإنسان بشيء … لكنه أيضا لا يمنعه من شيء … وما دام العقل قادرا على أن يتعلم … والقلب قادرا على أن يؤمن … فإن ��لمستقبل لم يقل كلمته الأخيرة بعد ⏳✨

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

حين نغير الطريقة ال��ي نكتب بها ... قد نغير أيضا الطريقة التي نفكر بها …

فالدماغ لا يتعامل مع الكتابة بوصفها نقلا للكلمات إلى الورق أو ��لشاشة … بل بوصفها عملية معرفية معقدة تجمع بين الحركة … والانتباه … واللغة … والذاكرة …

ولهذا … قد لا يكون الفرق بين القلم ولوحة المفاتيح في الحروف التي نكتبها ... بل في الشبكات العصبية التي نستخدمها أثناء ذلك …

[Oren Gottfried, MD @OGdukeneurosurg]

Fear

[The Lancet @TheLancet]

Ageing is associated with cognitive decline & an increased risk of neurodegenerative diseases.

A Review explores the neuroprotective mechanisms of endurance exercise & highlights the importance of cardiorespiratory fitness in healthy brain ageing: https://t.co/SjYUCfJ4Fw

[Ben Smith @bensmithlive]

A sleeping brain is still at work.

Nothing is more effective, and more ignored, than good sleep.

[William A. Wallace, Ph.D. @WilliamWallace]

Your body has a master clock hidden deep in the brain, and it quietly controls almost everything you feel during the day.
This chart shows what that clock is actually doing, and why your sleep, hunger, hormones, energy, and mood follow the same 24-hour rhythm every single day.

Here’s the simple breakdown:

⏰ The “master clock” lives in the "SCN" (as its abbreviated)
Located in the hypothalamus, it takes in light from your eyes and uses it to reset your entire system.
• Light in the morning tells your brain: wake up, raise cortisol, increase alertness.
• Darkness at night flips the switch: make melatonin, lower body temperature, prepare for sleep.

🌙 Melatonin rises only when the SCN says it’s dark
The pineal gland releases melatonin to start the sleep process.
If light hits your eyes at night (phones, TVs, bright LEDs), that signal can shut off or slow down.

😴 Serotonin and melatonin are linked
During the day, serotonin helps regulate mood and alertness.
At night, the system converts part of that serotonin into melatonin to drive sleep timing.

🧠 Your organs follow the brain’s schedule
Every major organ has its own “clock genes,” and they all sync to the SCN.
That’s why timing matters:

Daytime:
• Muscle: glycolytic metabolism and strength performance peak
• Liver: glycogen and cholesterol synthesis
• Pancreas: insulin secretion
• Fat: lipogenesis and adiponectin production

Nighttime:
• Muscle: oxidative metabolism and repair
• Liver: gluconeogenesis and mitochondrial biogenesis
• Pancreas: glucagon secretion
• Fat: lipid breakdown and leptin release (signals satiety)

In other words:
Your biology isn’t the same at 8 AM as it is at 8 PM.

🍽️ Food and activity act as “secondary clocks”
Eating late, irregular sleep, shift work, or inconsistent light exposure can confuse these clocks and throw off hormones, metabolism, and mood.

This is why:
• Morning light improves sleep
• Regular mealtimes stabilize metabolism
• Late-night eating increases glucose spikes
• Consistent sleep strengthens hormone rhythms
• Exercise timing can shift circadian signals

Your circadian rhythm isn’t just about sleep.
It’s a full-body timing system coordinating hormones, temperature, digestion, metabolism, and repair.

Get your light, food, and sleep aligned…
And the rest of your biology starts working with you instead of against you.

Graphic citation: Unknown
Research citation: PMID: 11584554

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

@talatalal792 Thank you Tala for your kind words! I’m truly proud of your enthusiasm and passion for learning.
Delighted you enjoyed the visit 😊 great things ahead for you, inshaAllah! 🤩

[Dr. Nasreen S. Basoudan 🧠🔍📚🖋️ @NBasoudan]

@balqees_mukhtar You’re most welcome, Balqees.
I’m pleased to know that the visit was beneficial for you, and I truly appreciate your kind words. Wishing you continued success 💐😊

[JAMA Neurology @JAMANeuro]

Frontotemporal #dementia is comparable in frequency to dementia with Lewy bodies and occurs at higher rates than progressive supranuclear palsy, corticobasal syndrome, and amyotrophic lateral sclerosis. https://t.co/B5kimsQmdI