NB

pharmacien 🇧🇪

[NB @NBpha]

@HeleneBsecours @MartinZ_uncut C’est ce que Monsieur Zizi prétend

[NB @NBpha]

@BrugadeJM Ben non c’est de la science, ne vous en déplaise

[NB @NBpha]

@BrugadeJM @MartinZ_uncut Est ce que j’ai parlé de l’efficacité du vaccin? j’ai juste dit qu’il n’y a aucun danger d’avoir des relations sexuelles avec « un vacciné »

[NB @NBpha]

@BrugadeJM @MartinZ_uncut Contact avec de la protéine spike seule (ex. : résidus théoriques de vaccin, fluides post-vaccination) → risque très faible à négligeable. Il n’y a pas de preuve de transmission de spike vaccinale dangereuse par contact sexuel ou buccal.

[NB @NBpha]

@HeleneBsecours @MartinZ_uncut Et donc?? comme monsieur Zizi le dit, vous confirmez qu’il est dangereux qu’un homme non vacciné aie des relations sexuelles avec une femme vaccinée ? Vraiment ?

[NB @NBpha]

@Orioso_Rohars @MartinZ_uncut Et que va-t-il se passer alors ?

[NB @NBpha]

@BrugadeJM @MartinZ_uncut Une muqueuse en contact avec une protéine … aucun danger ! Je ne change pas d’avis

[NB @NBpha]

@FauvelleSo57142 @MartinZ_uncut Mais non, evidemment que non, aucun risque de boire dans le verre d’un vacciné.
Ne vous inquiétez pas. (Il tente de vous faire peur, pas de raison d’avoir peur)

[NB @NBpha]

@MartinZ_uncut Pourquoi exiger un test du partenaire ? Je ne comprends vraiment pas ce qu’il peut y avoir de dangereux d’avoir un partenaire vacciné ? Pourriez-vous expliquer?

[The New York Times @nytimes]

JD Vance downplayed the significance of the Watergate scandal during a speech on Thursday, saying that the controversy that toppled President Richard Nixon would be “like a 12-hour news story” if it happened today. https://t.co/TTkFqpGzUG

[NB @NBpha]

@MartinZ_uncut Je vous cite : « Le virus n’a pas tué… » Vraiment ? Vous pensez vraiment ça ?

[Danielle Beckman @DaniBeckman]

Great to see @VirusesImmunity last paper highlighted at @NatRevImmunol. One of the strongest pieces of evidence yet for autoimmunity in #LongCOVID.
Not proof that autoimmunity explains all neurological Long COVID, but it's getting harder to dismiss as one important mechanism.

[Afshine Emrani MD FACC @afshineemrani]

2/5
Lipoprotein(a) — Lp(a).
This is 100% genetic. You can run marathons. Eat perfectly. Still have sky-high levels. 1 in 5 Americans are elevated, which triples heart attack risk.
You only need to check it once in your life because your levels are set at birth. The 2026 ACC/AHA guidelines now recommend everyone be tested.
Most people never have been.
Apolipoprotein B — ApoB.
For decades we've obsessed over LDL cholesterol. But LDL measures the cholesterol inside the particles. ApoB counts every single particle crashing into your artery walls.
A 2024 analysis found that 54% of patients had dangerous ApoB levels that standard LDL testing missed entirely. If you're only looking at LDL, you're driving with one eye closed.

[nature @Nature]

Eight of the top ten officials at the US National Institute of Allergy and Infectious Diseases have now been pushed out since President Donald Trump took office

https://t.co/Rzlr3WUOUv

[Harry Spoelstra @HarrySpoelstra]

Endothelial dysfunction and metabolic biomarkers in post-COVID-19 syndrome

🚨A nightmare study for many!

FOR EVERYBODY: 9 months after your COVID-19, your blood vessels are STILL damaged, with probably biomarkers to prove it!

1. Study design:
German prospective cohort (n=262 adults) compared blood biomarkers ~37 weeks post-SARS-CoV-2 infection (PCS patients + recovered) versus uninfected controls.

2. Endothelial dysfunction:
- Soluble thrombomodulin (sTM) and lactate dehydrogenase (LDH), two established markers of endothelial (blood-vessel) damage, were significantly elevated in the combined infected group (UOC PCS + LIFE Cov+) versus never-infected controls.

- So, previously infected individuals had significantly higher soluble thrombomodulin (TM) and lactate dehydrogenase (LDH), independent of PCS diagnosis or fatigue severity.

- Critically, there were no significant differences between the PCS group and the LIFE Cov+ group for these markers.

3. Metabolic disruption:
- Clear alterations in arginine biosynthesis and taurine/hypotaurine pathways, indicating impaired nitric-oxide (NO) metabolism with reduced L-arginine and taurine levels.

→In plain terms: the vascular damage signal was just as strong in the symptom-free recovered people as in those still suffering from fatigue and other PCS complaints. The same held for the metabolic disruptions (impaired arginine biosynthesis and taurine/hypotaurine pathways linked to nitric-oxide production).

4. Fatigue-specific signal:
- High-fatigue PCS patients (top MFI-20 quartile) showed elevated linoleic acid (LA) plus monounsaturated fatty acids oleic (OA) and palmitoleic (PA).

→The fatty-acid signature specific to high-fatigue PCS adds a potential severity marker.

5. Notes:
- Changes persisted already up to 9 months after infection.
- PCS remains symptom-based, but these markers offer objective, measurable signals of underlying vascular and metabolic damage!
-The discussion and results treat the observed endothelial and metabolic changes as consequences of a single infection and do not speculate on additive damage from subsequent exposures.
- Limitations well noted.

‼️So, COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms.
Specific fatty-acid spikes flag severe post-COVID fatigue. The “it’s all in your head” narrative for many post-covid people is directly contradicted by these biomarkers!
These findings, solidly backed by prior 2021–2025 evidence, prove that COVID-19 inflicts measurable, persistent endothelial and nitric-oxide metabolic damage up to nearly a year later, even in fully symptom-free survivors, thereby supporting the implementation of routine biomarker screening, but even more importantly: #AvoidSars2 #AvoidReinfections. YOU ARE NOW A CV RISK PATIENT!
https://t.co/dkyr9HXTyO

[The New York Times @nytimes]

Breaking News: The FDA has blocked publication of research that found widely used Covid-19 and shingles vaccines were safe. https://t.co/P4ZNeIfvPV

[NB @NBpha]

@MartinZ_uncut Et quand les symptômes du « covid long » sont survenus avant que le vaccin n’existe …c’est aussi de la faute du vaccin?

[Michael McFaul @McFaul]

Zelenskyy did not start a war!

Putin invaded his country!

So embarrassing when the president of my country says such things.