Dr Srinidhi V

Nephrologist & Transplant Physician | GlomCon Fellow
📚 Notes 🧠 Concepts 📝 Clinical pearls
🔎 Interesting reads
Stay curious. Keep learning. Keep growing.

[Dr Srinidhi V @NephroNook]

From altered renal hemodynamics to direct tubular injury, myoglobin-mediated toxicity, and immune-complex deposition, dengue-associated AKI reflects a complex interplay of mechanisms.

Recognizing these pathways adds another layer to understanding severe dengue.

#NephroNook

[Dr Srinidhi V @NephroNook]

Dengue and the kidneys 🦟🫘

Acute kidney injury is an important, yet often underrecognized, complication of dengue.

What makes dengue-associated AKI multifactorial? Let’s look at the mechanisms. 🧵

#NephroNook #AKI #Sri's pages #NEET

[Dr Srinidhi V @NephroNook]

Dengue can injure the kidneys through multiple routes:

🩸 Hemodynamic compromise
🫘 Tubular and glomerular injury
💪 Rhabdomyolysis with pigment nephropathy
🧬 Immune-mediated damage

The final common pathway? Acute kidney injury.

[Dr. Hardik Patel 🩺���� @hardik4u24]

✨The gut–kidney axis in CKD 🫘

🧪 Uremia → weakened gut barrier
🔓 Microbial products cross
🔥 Inflammation may fuel further kidney decline
🔄 A potential vicious cycle

🔗https://t.co/CZ92bmLnTd 🆕

#CKD #Nephrology

[Dr Srinidhi V @NephroNook]

7/
SUMMARY

A beautiful summarised representation of the various mechanisms leading to AKI in Malaria infection

#NephPearls #AKI #Sri's pages #NEET

[Dr Srinidhi V @NephroNook]

Tropical infection related AKI

1/ Malaria - AKI - A thread

There are 5 species of Plasmodium

1. Plasmodium falciparum - The most severe and responsible for majority of Mortality and renal injury - INFECTS RBC'S OF ALL AGES

#NephPearls #AKI #Sri's pages #NEET

[Dr Srinidhi V @NephroNook]

6/ Most frequent renal pathologies in Malaria-associated AKI

📍ATI, ATN (Acute tubular injury/necrosis)
📍MPGN
📍TMA
📍Bile cast nephropathy
📍Pigment nephropathy - due to hemolytic, rhabdomyolysis

#NephPearls #AKI #Sri's pages #NEET

[Dr Srinidhi V @NephroNook]

Samih Nasr Diagnostic criteria

#NephPearls #IRGN #Sri's Pages

[Indian Society of Nephrology @isn_india]

The Weekly Nephron is back!

And the Onconeph fever is not over yet.

📝We have yet another paper (an accepted manuscript rather) @CKJsocial guiding us on a practical and confusing question!

This week’s 🧵 is by @DrAkshayaJ

@ERAkidney @PepaSolerR @ClaraGCarro @simeoni_m

[Dr Srinidhi V @NephroNook]

Transplant immunology - Basics
An overview

#NephPearls #Transplant #Sri's Pages

[Dr Srinidhi V @NephroNook]

Dyslipidemia in Chronic Kidney Disease
#Nephrology #CKD
https://t.co/EqurGpGQOk

[Dr Srinidhi V @NephroNook]

Growing significance of the complement system in glomerular diseases, with an expanding therapeutic repertoire.
#Nephrology #Complement
https://t.co/Utjj87bXUr

[Dr Srinidhi V @NephroNook]

@ISNeducation @Dilushiwijay @ISNkidneycare @myadla @drpradeeplotus @RadhikaDrpatil Congo red

[Dr Srinidhi V @NephroNook]

@ISNeducation @Dilushiwijay @ISNkidneycare @myadla @drpradeeplotus @RadhikaDrpatil Native medicine intake..??