Manuel Neumann

plant computational biologist @Cambridge_Uni fascinated by studying the link between regulome, transctriptome and phenotype
🌸💻 🏊‍♂️🏃‍♂️🥾

[Manuel Neumann @Neumann_M_]

Huge thanks to all co-authors, especially Xiaocai and Freddy, for making this possible 🙏 #Genomics #PlantBiology #ArabidopsisThaliana #NewPaper #TranscriptionFactors #PioneerFactors

[Manuel Neumann @Neumann_M_]

🎉 Very happy to share that our 5+ years of work "AP1 is a pioneer transcription factor that programmes cell fate through MADS‑domain protein tetramerisation" is finally published in Genome Biology @GenomeBiology: https://t.co/dMcshZwIAW

[Manuel Neumann @Neumann_M_]

We show that APETALA1 (AP1) acts as a pioneer transcription factor in Arabidopsis thaliana — facilitated by tetramerisation. We demonstrate that it can access closed chromatin, open it, and trigger the gene-regulation cascade that drives floral identity.

[Manuel Neumann @Neumann_M_]

Great work with @SiyeChen95
#PlantBiology #SingleCell #Arabidopsis

[Manuel Neumann @Neumann_M_]

Excited to share our new preprint! 🌸
We used single-cell RNA-seq to chart the cellular landscape of A. thaliana floral epidermal development — uncovering key cell types and gene expression dynamics.
📄 Read it here: https://t.co/AcKjHnyAQR

[Manuel Neumann @Neumann_M_]

@paulvilloutreix Thanks for having me and the great discussion!

[Manuel Neumann @Neumann_M_]

@paulvilloutreix Beautiful place. Enjoy!

[Maria Rutkiewicz, PhD @MariaRutkiewicz]

I loved the collaborative environment at @MDC_Berlin and now I'm happy to share some results of our work with you: https://t.co/jPdF8NSkjN

[Laleh Haghverdi @LH33837868]

scRNA-seq datasets almost never present a balanced sampling of their included cell types. What are the implications of this for labels transferred to query data? And a few other cool things one ought to know about label transfer. Check our preprint :)

[Manuel Neumann @Neumann_M_]

Context-specific functions of transcription factors controlling plant ... https://t.co/DO83tTTVcq
#genomics #PlantScience #DevBiology

[Manuel Neumann @Neumann_M_]

ChIP-Hub, an integrative platform for exploring the plant regulome.
Really great resource!
https://t.co/SfGb2eutDY

[Manuel Neumann @Neumann_M_]

@uhammes delicious!

[Manuel Neumann @Neumann_M_]

Beautiful hike today on Sierra de San Julián after WMMCF 2022 in Alicante.

[Manuel Neumann @Neumann_M_]

Our work on predicting 3D gene expression profiles is finally published. Many thanks to all people involved in this.
@XUXIAOCAI @JoseMMuino1 @CezarySmaczniak @thomas_greb
#3DgeneExpression #genomics #PlantScience #DevBiology
https://t.co/cUVngVeEGz

[Manuel Neumann @Neumann_M_]

SINFONIA - a multinational initiative to understand transcriptional and post-transcriptional mechanisms driving plant development. Our recent pre-print gives an overview of the background and directives of SINFONIA. We welcome other groups to join.
https://t.co/zWi74hbLiq

[Oleg B⌬r⌬din 🇺🇦 @Borodin_O_]

My paper is finally out! ☺️ Many thanks to @mvdelius for continuous support and to all other people who contributed to this work (special thanks to @CraigCR 🙏🏻).
I’m also very grateful to @FieldenStephen and @ProfDaveLeigh for inspiring me with their work https://t.co/6gjpRRgM9K

[Manuel Neumann @Neumann_M_]

@Borodin_O_ @mvdelius @CraigCR @FieldenStephen @ProfDaveLeigh congrats Oleg! so happy for you that your work on this is out now.

[Manuel Neumann @Neumann_M_]

@AltunaAkalin @MDC_Berlin Thanks @AltunaAkalin and his group for offering this years course. Very much enjoyed it.

[William J. Greenleaf @WJGreenleaf]

Excited to announce that our paper describing NEAT-seq, a method to simultaneously measure transcription factor protein abundance, ATAC-seq, and RNA-seq in single cells, is out on biorxiv! Congrats to Amy and Ben! https://t.co/XJh5TndOcj

[Manuel Neumann @Neumann_M_]

@Ma__Leonard @SenUVKBerlin @BA_Pankow Kann man von Glück reden, dass da nicht mehr passiert. Gibt aber auch Radfahrer die bei Rot drüber fahren.