An altered gut barrier function has been involved in conditions beyond the gut. Researchers have found that, in people with alcohol use disorder, the gut microbiota can induce changes in liver metabolism, leading to altered social behaviors & depression https://t.co/FoAX07EMgy
Microbial metabolism can affect antibiotic susceptibility. This new review in @iScience_CP characterizes environmental & microbial drivers of antibiotic susceptibility within the gastrointestinal tract to predict in vivo antibiotic activity https://t.co/9Nh9s3I36U
The modulation of the nervous system by the microbiota is an active area of research. This SR disentangles the influence of the gut microbiota on brain (it's still difficult to say if changes in gut microbiota are cause or consequence of mental disorders) https://t.co/Sr1gfGtr86
The vitamin D receptor is highly expressed in the gastrointestinal tract. New findings reveal that men with higher levels of 1,25(OH)2D and higher activation ratios are more likely to possess butyrate producing bacteria linked to better gut health https://t.co/iLUxO2sPl5
Vagal afferents can carry signals on the functional state of the gastrointestinal tract as well as messages from bacterial byproducts. Why changes in the gut microbiota might be worth considering in the pathophysiology of neurological disorders? https://t.co/ewHlc8OGyD
We've learned that our gut health and especially gut microbes are closely connected with brain physiology. This new review focuses on the role of the oral microbiota, probiotics and prebiotics in shaping the gut microbiota in schizophrenia https://t.co/SJEk57bdOX
The long used Firmicutes-to-Bacteroidetes ratio alone may not be a reliable indicator of gut microbiota composition and its association with overall health https://t.co/EGcULijqwI
Gut–brain connections may be mediated by a wealth range of actors. This perspective covers neurological disorders and models associated with shifts in gut microbiota, with a particular focus on the role of microbial metabolites https://t.co/jkB0h0ECq0
Gut microbiome-targeted interventions are being explored as means of improving mental health. A new meta-analysis of 22 randomized controlled studies has found no significant effect on improving cognition for probiotics, prebiotics and fermented foods https://t.co/CcAnSI9TFp
Therapeutic approaches targeting the gut-brain axis may represent the next avenue for the treatment of psychiatric disorders. This new review in @FrontImmunol covers reciprocal interactions between gut microbes and the CNS during experimental disease https://t.co/SC2FWMOyQw
[NEW POST] A new meta-analysis of randomized controlled trials concludes that it is too early to recommend probiotics, prebiotics or fermented food interventions for improving cognitive outcomes.
https://t.co/IUU3YlBMbq #gutmicrobiome
The functional implication of the gut microbiome in Alzheimer's disease remains elusive. New findings in 89 older persons show a novel association between SCFAs and LPS and systemic inflammation with brain amyloidosis via endothelial dysfunction https://t.co/j3TE2NfxTb
Postbiotics are metabolites or components of the microbiota with effects on the human health. This review updates their implication at the intestinal and systemic levels https://t.co/2vWbfOA6G8
Quorum sensing-regulated secretions can modulate intestinal physiology in multiple ways. In this context, bacterial mediators have a direct influence microbiota-gut-brain axis signaling pathways via @iScience_CP https://t.co/q0gLbvI0YX
Metabolites of microbial origin are important regulators of innate immune responses. For instance, butyrate-induced antimicrobial activity has recently been found to be associated with a shift in macrophage metabolism https://t.co/rcQeREMnUY
Parasitic intestinal worms and gut bacteria occupy the same space. New cross-sectional data reveals there is considerable interplay between helminths, micronutrients and the microbiota on the regulation of immune responses in humans via @PLOSPathogens https://t.co/kCVVtkqi2A
Akkermansia muciniphila is an attractive commensal gut bacteria to study because of its probiotic effect. Scientists have shown how bile acids can impact the growth and global gene expression profiles in A. muciniphila https://t.co/UQjWxPXJAI