Nishanth Ulhas Nair

Scientist working on Computational Biology. Interested in cancer research. Student of Yoga.

[Nishanth Ulhas Nair @Nishanth_UN]

Thrilled to share our new work now out in @Annals_Oncology! BRIDGE predicts #breastcancer neoadjuvant therapy response from tumor transcriptomics — and BRIDGE-Slide brings this to routine H&E slides via deep learning. No sequencing needed. Precision Oncology, democratized. 🧵👇

[Eytan Ruppin, MD, PhD @EytanRuppin]

🚨 Our pre-proof is out on @Annals_Oncology!

BRIDGE, a framework to quantify intratumoral subtype mixtures in #BreastCancer and predict neoadjuvant response, including directly from H&E slides

Paper: https://t.co/VxSklz9oVH

🧵1/11

[Nishanth Ulhas Nair @Nishanth_UN]

Happy to see that our work has been featured in the Cedars-Sinai Newsroom! #breastcancer #AI #precisiononcology @EytanRuppin @cantore_thomas
https://t.co/SyadW7tCxN

[Nishanth Ulhas Nair @Nishanth_UN]

Thrilled to share our new work now out in @Annals_Oncology! BRIDGE predicts #breastcancer neoadjuvant therapy response from tumor transcriptomics — and BRIDGE-Slide brings this to routine H&E slides via deep learning. No sequencing needed. Precision Oncology, democratized. 🧵👇

[.RW🦦 @pacyuzu]

He risked his own life to save a child from a crocodile. ❤️🐊

[Erik Solheim @ErikSolheim]

Please watch! This is simply wonderful!

China 🇨🇳 bringing every citizen out of extreme poverty.

India 🇮🇳 bringing hundreds of millions into a better life!

[Sadhguru @SadhguruJV]

The International Day of Yoga is a reminder that what we call Yoga is not a philosophy, an ideology, a belief system or a religion. This is the science and technology for inner wellbeing. Whatever your religion, race, caste, creed, gender, these technologies render you to optimal existence - to peak performance in body, mind, emotion, intelligence and energies and above all, it will unlock the potential of the genius that is in every human being. -Sg

[Imtiaz Mahmood @ImtiazMadmood]

Indian and Swiss snowboarders Urmila and Linda hitting the slopes of Gulmarg, India in traditional sarees.

[Daniel Di Martino @DanielDiMartino]

Immigration chart of the day.

Indian immigrants have the highest household income of any country of birth in the United States.

Among the top 20 immigrant groups, Hondurans have the lowest incomes.

[Daniel Di Martino @DanielDiMartino]

Immigration chart of the day.

Incarceration rate of men in the United States by origin.

Native Americans and Blacks have the highest incarceration rate by far.

Central Americans and Mexicans are incarcerated more than whites.

South Americans are similar to native-born Asians.

[Annals of Oncology @Annals_Oncology]

🆕BRIDGE (BReast Intra-tumoral Deconvolution of Gene Expression) can predict response to neoadjuvant therapy by deconvolving transcriptomes of breast tumors and estimating their subtype composition
For the full article see:
https://t.co/WWubQsKUVr

[Nishanth Ulhas Nair @Nishanth_UN]

Co-led with the brilliant @cantore_thomas — couldn't have done this without him. Huge thanks to @danhtai_hoang for his contribution, and as always, grateful to my mentor @EytanRuppin for his vision and guidance. Honored to be a co-corresponding author. Thanks to all co-authors!🙏

[Nishanth Ulhas Nair @Nishanth_UN]

Thrilled to share our new work now out in @Annals_Oncology! BRIDGE predicts #breastcancer neoadjuvant therapy response from tumor transcriptomics — and BRIDGE-Slide brings this to routine H&E slides via deep learning. No sequencing needed. Precision Oncology, democratized. 🧵👇

[Eytan Ruppin, MD, PhD @EytanRuppin]

🚨 Our pre-proof is out on @Annals_Oncology!

BRIDGE, a framework to quantify intratumoral subtype mixtures in #BreastCancer and predict neoadjuvant response, including directly from H&E slides

Paper: https://t.co/VxSklz9oVH

🧵1/11

[Eytan Ruppin, MD, PhD @EytanRuppin]

Preprint alert! #AI

Can routine H&E slides decode tumor spatial heterogeneity in #HeadAndNeckCancer? Meet HEiST, a deep learning framework applied to 1,500 #HNSC tumors: most comprehensive spatial #TME analysis!

📜https://t.co/Bs6464yWdE

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[Alexandr Rakitko @AlexRakitko]

🧬Can chemotherapy response in aggressive breast cancer be predicted from the tumor “ecosystem”?

New @Nature study shows that single-cell RNAseq and spatial transcriptomics can predict response to chemotherapy in triple-negative breast cancer (model reaching AUC = 0.84).

Triple-negative breast cancer is an aggressive breast cancer subtype lacking estrogen, progesterone, and HER2 receptors, which limits targeted treatment options and keeps chemotherapy central.

Tumors that responded better to chemotherapy more often showed:
- Interferon signaling in cancer cells — a sign of immune alert.
- Higher HLA class II expression �� potentially making tumor cells more visible to the immune system.
- More actively dividing cells, especially in S phase, which chemotherapy can hit more effectively.

Triple-negative breast cancer is not one disease, but a set of distinct cellular ecosystems. And the structure of that ecosystem may help predict whether chemotherapy will work.

https://t.co/O6eKE1BUrl

#Cancet #SpatialTranscriptomics #RNAseq #SingleCell

[Eytan Ruppin, MD, PhD @EytanRuppin]

🚨 Out today in Cell! @CellCellPress

Path2Space: #AI that predicts spatial transcriptomics (ST) from H&E pathology, enabling spatial biomarker discovery in #BreastCancer at scale.

📄 https://t.co/GtrmH9zIDs

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[Smita Prakash @smitaprakash]

Indus Treaty worms coming out of various 'news' portals. Deep state actors have been activated on the India-Pakistan water issue.

[Sadhguru @SadhguruJV]

The New Year marks a period of heightened solar intensity in the northern hemisphere that impacts all life on the planet. It is my wish and my blessing that you use this natural support to become an exuberant Life and commit to making yourself into wonderful human being and creating a wonderful world to the extent you can. -Sg #TamilNewYear #Vishu #Bihu #Baisakhi #PanaSankranti #PoilaBoishakh #Vaisakhadi

[Sadhguru @SadhguruJV]

Congratulations to all scientists and engineers who have worked for over two decades to achieve this milestone. The fast breeder reactor is critical to securing long-term clean & affordable energy for a surging Bharat. Most important to prioritize safe disposal of waste. Best wishes & blessings. -Sg

[Arvind Panagariya @APanagariya]

My dear Kaushik, to reassure you that growth is not enriching only those already rich, here are the poverty numbers from an article in the March 7 2026 issue of the EPW (TPL in the table stands for the Tendulkar Poverty Line)

[Tejasvi Surya @Tejasvi_Surya]

In 1960, South Korea’s per capita income was $94. India’s was $82.

China was neck and neck with us through the 1970s, India was actually ahead of China in 1980.

But today Korea is 13 times richer than us in per capita terms, China is 5 times richer, Singapore is 38 times richer.

Same starting point, just one difference, they freed their people to build. But the License-Permit-Quota Raj of Congress caged our economy and wealth creators.

[James Zou @james_y_zou]

Today in @NatureMedicine we report that AI can predict 130 diseases from 1 night of sleep🛌

We trained a foundation model (#SleepFM) on 585K hours of sleep recordings from 65K people—brain, heart, muscle & breathing signals combined.

AI learns the language of sleep🧵

[Sidhant Sibal @sidhant]

Hindu Businessman Khokon Chandra Das attacked in Shariatpur, Bangladesh. Petrol poured on him. Survives: Bangladesh media