TJ Cradick

CRISPR Chief Scientific Officer
Alum: @HuidaGene @ExcisionBio @CRISPRTx @GeorgiaTech @SangamoTx @UIowa @UCSF @MIT Tweets = own. plus Bsky

[TJ Cradick @NucleaseLab]

I presented at the #LotFUSA2024 conference today on 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀, 𝗠𝗮𝗰𝗵𝗶𝗻𝗲 𝗟𝗲𝗮𝗿𝗻𝗶𝗻𝗴 𝗮𝗻𝗱 𝗼𝘁𝗵𝗲𝗿 𝗖𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗠𝗲𝘁𝗵𝗼𝗱𝘀 𝗳𝗼𝗿 𝗡𝗲𝘅𝘁-𝗚𝗲𝗻 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲𝘅 #𝗖𝗥𝗜𝗦𝗣𝗥 punctuated with lessons from ZFNs and TALENS

[TJ Cradick @NucleaseLab]

Exciting rainbow photo effects, as some of the rooms used DLP projectors and the iPhone photos picked up the spinning of the color wheel

[TJ Cradick @NucleaseLab]

My Day 2 talk at #AdvancedTherapiesUSA, “New delivery technologies that target new unmet disease indications” focused on how #AAV , #LNP and other delivery sets the addressable disease space.

#CRISPR #GeneTherapy

[TJ Cradick @NucleaseLab]

Conferences discussions with friends and colleagues are as integral as presentations.
At #AdvancedTherapiesUSA, I was therefore excited to #MeetFirst Kate Excoffon and discuss #AAV and the Emerging Trends in Gene Therapy, the topic of her Day 1 panel
#CRISPR #CGT

[TJ Cradick @NucleaseLab]

Day 1 of the #AdvancedTherapies Congress at #Boston's Hynes Convention Ctr.
I am excited to chair the Panel on Innovation In Gene Editing, where we will be discussing Leveraging Platform Technologies to Enhance Development Efficiency

#GeneEditing  #CRISPR  #LNP #AAV

[TJ Cradick @NucleaseLab]

Thrilled to present at #MSS2026 in Slovenia 🇸🇮 on how #GeneEditing Therapeutics address Unmet Medical Needs.
It’s been an inspiring event covering the cutting edge of Gene Therapeis, #CGT,  #Vaccines, Delivery, and  Biomanufacturing.

[TJ Cradick @NucleaseLab]

@RySciComms Dolly was certainly someone who was appreciate by everyone.

[TJ Cradick @NucleaseLab]

@bradloncar @daphnezohar What? When in Kendall Square, it is 1/2 mile to nearest Taco Bell (just had to look up).

[TJ Cradick @NucleaseLab]

@RySciComms https://t.co/LlLM4UK9ZJ

[TJ Cradick @NucleaseLab]

Wondering How #WorldCup2026 Breaks Ties ?
Ranking when all tied (Group H & I) or are tied after 3 games?
1. Points
2. Goal Differential
3. Goals Scored
4. Conduct Score (fewer yellow and red cards)
5. FIFA/Coca-Cola Men's World Ranking

[TJ Cradick @NucleaseLab]

@MayoClinic @minnesotalynx This looks like something we should be doing regularly. Can we do this while in the waiting room?

[TJ Cradick @NucleaseLab]

https://t.co/E9ISEQduWq

[TJ Cradick @NucleaseLab]

Wonder which uniforms will be worn in #FIFAWorldCup?
Wonder no more: FIFA details full Match Team Colours even what the Ball Kid will be wearing.

FIFA World Cup 2026™ - Canada, Mexico and the United States
#WC26 #WeAre26, #WorldCup #WorldCup2026.

[TJ Cradick @NucleaseLab]

"#FIFAWorldCup groups separated by head-to-head records for first time" now trending, though the @FIFAcom page, linked below, is still up.
A giant change & how teams can get locked in after 2 games.
The other #FWC26 steps follow after head-2-head

[TJ Cradick @NucleaseLab]

Wondering How #WorldCup2026 Breaks Ties ?
Ranking when all tied (Group H & I) or are tied after 3 games?
1. Points
2. Goal Differential
3. Goals Scored
4. Conduct Score (fewer yellow and red cards)
5. FIFA/Coca-Cola Men's World Ranking

[TJ Cradick @NucleaseLab]

"World Cup groups separated by head-to-head records for first time" now trending, though the FIFA page, linked below, is still up.
A giant change & how teams can get locked in after 2 games.

The other steps follow after head-2-head

[TJ Cradick @NucleaseLab]

Wondering How #WorldCup2026 Breaks Ties ?
Ranking when all tied (Group H & I) or are tied after 3 games?
1. Points
2. Goal Differential
3. Goals Scored
4. Conduct Score (fewer yellow and red cards)
5. FIFA/Coca-Cola Men's World Ranking

[TJ Cradick @NucleaseLab]

#WC26 Details
https://t.co/CrlEsKNLlq

[TJ Cradick @NucleaseLab]

Is there a way to sign up to get notified for super exciting, close World Cup games?
For example #2 in the World Spain is tied with Cape Verde with 10 min left!!

And why is no one calling the 'hydration break' the FIFA Quarter Commercial Breaks?

[TJ Cradick @NucleaseLab]

@bradloncar How else are they suppose to find exclusives ?

[TJ Cradick @NucleaseLab]

Leveraging Prior Knowledge in the Development of Human Gene Therapy Products Incorporating Genome Editing Draft Guidance
can be downloaded from
https://t.co/veePCmKEet

[TJ Cradick @NucleaseLab]

New FDA guidance for Cell&Gene Tx / #GeneEditing can use public / previous CMC, non- &  clinical info,
including OFF-TARGET* data, to streamline reg submissions.
Builds on Plausible Mechanism guidance.

Keep Leveraging this Prior Knowledge!

*msg to discuss specificity data

[TJ Cradick @NucleaseLab]

Great to spend time with fellow #BLPN founding members at #ASGCT2026