Osteoarthritis and Cartilage Journals

Osteoarthritis and Cartilage, and Osteoarthritis and Cartilage Open - official journals of @OARSInews. Impact factor 9. co-EiCs: @AM_Malf & @ProfDavidHunter

[UCSF Center for Intelligent Imaging @UCSF_Ci2]

What role does the infrapatellar fat pad play in knee OA? A study of 4,257 OAI participants by @UCSF_Ci2's Dr. @ThomasMLink1 & colleagues used DL-based automatic volumetric segmentation to investigate subregion-specific associations. More in @OACJournal: https://t.co/xM9vBLOdH3

[Osteoarthritis and Cartilage Journals @OACJournal]

Zhu et al. investigated the role of Growth Differentiation Factor 10 (GDF10) in Osteonecrosis of the femoral head–associated cartilage degeneration (ONFH-ACD). GDF10 limits fibrosis and supports cartilage matrix synthesis via SMAD1/5/8 and SMAD2/3.
https://t.co/8wPpPrYcML

[Osteoarthritis and Cartilage Journals @OACJournal]

Articular #cartilage has a unique extracellular matrix, but its repair capacity is limited. Protein-level adaptations remain poorly characterized in large-animal models. This work uses #proteomics to study the trajectory of cartilage maturation!

https://t.co/2EyVAcVUNc

[Osteoarthritis and Cartilage Journals @OACJournal]

⚠️ Reminder to check before you cite.

More than 140 #osteoarthritis related studies identified on #retractionwatch that we should be aware of (see papers in comments)

https://t.co/bteQmxnbY8

[Osteoarthritis and Cartilage Journals @OACJournal]

A complementary medicine combo of Boswellia serrata extract, #pinebark extract, #MSM, #curcumin, and #piperine was not superior to placebo for improving OA pain over 12 weeks

Read more by Shiwen Yuan et al. in this month's issue - https://t.co/l5PJJ5HicE

[Osteoarthritis and Cartilage Journals @OACJournal]

Knee brace adherence in this month's issue 👇

Self report ≠ real-world wearing time

A temperature sensor to monitor brace adherence in knee OA found that self-report adherence substantially #overestimates knee brace wearing time

https://t.co/wbewoXqO2g

[Osteoarthritis and Cartilage Journals @OACJournal]

New this month 👀

Read all about OA prevalence, incidence, and progression and risk factors in this updated #epidemiological synthesis by Golightly et al.

https://t.co/ns9tcz6Ykd

[Osteoarthritis and Cartilage Journals @OACJournal]

Early cartilage degeneration in the shoulder mirrors patterns seen in weight-bearing joints. Raman spectroscopy and biomechanics helped researchers identify matrix changes and bone alterations, paving the way for non-invasive OA diagnostics.
@NazarianLab
https://t.co/GYluiPthlK

[Osteoarthritis and Cartilage Journals @OACJournal]

⚠️ Oct's Clinical Editors Choice is on #methotrexate

This study builds on the #PROMOTE trial & identified IFN-γ, TNF-α, IL-15 and IL-16 and hs-CRP as potential markers to stratify the treatment response to methotrexate in knee #OA

@WattImperial
https://t.co/TevoPbFZ23

[Osteoarthritis and Cartilage Journals @OACJournal]

More from #OAC! This study by Su et al. aimed to elucidate how organic–inorganic assembly and residual stress contribute to interfacial mechanical integrity.

Read more🔗: https://t.co/PGCtBkINfH

[Osteoarthritis and Cartilage Journals @OACJournal]

New in #OAC! Phase-contrast synchrotron microtomography of human articular #cartilage samples reveal age-related changes with similar fidelity as histology, while providing substantial additional quantitative information.
Read more: https://t.co/rkXE7dVzo3

[Osteoarthritis and Cartilage Journals @OACJournal]

New in #OAC!
Schwab et al. aimed to develop a method to selectively study the zone of calcified #cartilage (ZCC) for gene expression analysis and transcriptomic studies. Learn how 3D microtomy was used to isolate #RNA from fresh human ZCC!
🔗
https://t.co/ivO3Ev4t2l

[Osteoarthritis and Cartilage Journals @OACJournal]

Public Service Announcement 🔔

A new submission experience will soon go live for from Oct 19.

This process will be faster, more streamlined, and more user-friendly 😃

More information in the video below: https://t.co/5Z17yuW3Pd

[Osteoarthritis and Cartilage Journals @OACJournal]

New in #OAC! Learn about how Kundu et al. characterized aging-osteoarthritis (OA) innervating nerve networks in mouse knee joints using tissue-cleared 3D light-sheet microscopy.
🔗https://t.co/IN5LBdckOa

[Osteoarthritis and Cartilage Journals @OACJournal]

📑 CALL FOR PAPERS

Are you researching how joint-level and whole-body mechanics interact with the multifactorial nature of hashtag#osteoarthritis?

Consider submitting your manuscript to our special hashtag#biomechanics issue - https://t.co/htj5FXLcX8

Deadline: April 15, 2027

[Osteoarthritis and Cartilage Journals @OACJournal]

✋ 👀 This study looked at 1180 #postmenopausal women over 14 years and found that erosive hand osteoarthritis is associated with increased risk of incident osteoporotic fractures

Read more from Maxime Auroux et al. in this month's issue - https://t.co/EpQEkSBoor

[Osteoarthritis and Cartilage Journals @OACJournal]

#Adiposity was associated with poorer outcomes for knee-related QoL and functional performance for females but not males.

Read for free from Indiana Cooper et al. in this month's issue - https://t.co/uh9q8nDayC

[Osteoarthritis and Cartilage Journals @OACJournal]

New this month!

Can #radiomics analysis of hand radiographs automate assessments of structural severity in hand #OA?

Read more from Laetitia Perronne et al. in this month's issue - https://t.co/10VL9AqsZi

[Osteoarthritis and Cartilage Journals @OACJournal]

Lai et al. uncovers a multi-switch mechanism in cartilage mechanobiology: ADAMTS5��aggrecan binding switches between stable and unstable states at distinct force levels. This explains how moderate vs. excessive loading differentially drives ECM degradation.
https://t.co/mo5VAS4pVl

[Osteoarthritis and Cartilage Journals @OACJournal]

🤯 It is September already and this month's #editorschoice is the first in our #OA Fundamental Series

Read all about OA #diagnosis and #assessment in this free-to-read article by Lauren King and Abhishek - https://t.co/2CkgBbpiPi