Mustafa A. H. El Darawany, MD

Anatomic pathology MSc, PhD, Histopathology, FOM-SCU☪️🇪🇬, Free 🇵🇸

[Janira Navarro @Janiranavarro]

***Lepidic pattern is not limited to primary lung tumors***

- Female patient with history of breast cancer now with lung lesion (pic 1 and 2): Mesothelioma, epithelioid type
- Melanoma (pic 3)
- Cholangiocarcinoma (pic 3)

Practical lession: Lung tumors that looks like carcinoma but negative for TTF-1 and p40, add Claudin 4 and WT-1 to exclude the possibility of mesothelioma

Dr. Sauter #USCAP2026 #pathology #PathX #PathTwitter

[Janira Navarro @Janiranavarro]

Oropharynx exophytic lesion: SCC?

Tonsillar crypts are lined by a unique reticulated epithelium. The basement membrane is disrupted and non-contiguous, allowing the epithelium easy access to lymphatics.

- There is no crypt dysplasia or in situ carcinoma in oropharyngeal HPV+ SCC.
- All HPV-related neoplasia of the tonsils should be regarded as malignant even in the absence of "classic" histologic features of invasion.

Dr. Cipriani #USCAP2026 #pathology #PathX #PathTwitter

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Rosai-Dorfman disease in skin -somebody please call the police - the emperipolice! An S100 protein stain highlights the nuclei (arrow) and cytoplasm of abnormal histiocytes but not the engulfed inflammatory cells in the cytoplasm (emperipolesis - engulfment without destruction).

[Mustafa A. H. El Darawany, MD @Paraffinembeded]

@EmanMagdy91D Ma shaa' Allah, insightful demonstration dear dr. Eman 👌

[Lisa Rooper @LisaRooperMD]

A morphologic mosaic of NUT carcinoma: monotonous primitive cells, basophilic to clear cytoplasm, abrupt keratinization, prominent tumor infiltrating neutrophils. Confirm with speckled nuclear positivity for NUT1 IHC, BRD4-NUT fusion or variants. #ENTPath #PulmPath #SurgPath

[Eman Magdy @EmanMagdy91D]

Polymorphous Adenocarcinoma
Pleomorphic Adenoma
Myoepithelioma

Salivary gland pathology

#pathology

[Janira Navarro @Janiranavarro]

Adrenal rest and endometriosis in fallopian tube

Adrenal rest (Pic 1 and 2)
Endometriosis (pic 1)

#everydayGYN #pathology #PathX #pathtwitter

[Dr. Bui Pathologist🌼 @DrBuiPathology]

#DrBuiBSTCaseCollection This is a hybrid Schwannoma and neurofibroma. #pathX #pathtwitter ⁦@MoffittNews⁩ ⁦@USFpathology⁩ ⁦@CAPA_comm⁩

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Ugh. Melanoma fooled me. Two initial immunostains (desmin and actin) were negative - I regrouped and sorted it out. Not the first time - won't be the last. Melanoma's always there to humble us. #UMiamiPath

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Such a perfect example of hepatic focal nodular hyperplasia with the classic "map-like" glutamine synthetase immunohistochemical staining pattern. Note that the adjoining normal liver tissue lacks that pattern. #UMiamiPath

[Pathology mcqs @Pathology_mcqs]

Difference between Goblet cells and Pseudogoblet cell, an important pitfall in the diagnosis of Barrett esophagus.
GI pathology- #gipath #gipathology #pathologymcq #adenoma #barett #gastric
#frcpathhistopathology #frcpath #frcpathpart1 #neetssoncopathology

[Ahmed Montasser @AMontasserMD]

M 29 Y, Orchiectomy, 13mm nodule:

Large cell calcifying sertoli cell tumor (LCCSCT)

• Trabeculae of polygonal cells with eosinophilic cytoplasm in myxoid stroma.
• Calcifications of variable sizes and shapes.
• Neutrophilic infiltrate, lymphocytic rim.

#GUpath #Pathology

[Janira Navarro @Janiranavarro]

Patients with squamous cell carcinoma and margin evaluation in retromolar trigone -frozen sections pitfall ⚠️

Juxtaoral organ of Chievitz:
- Benign epithelial cords in nerve rich stroma
- Lobulated
- Well circumbscribed nest, cytologically bland

Dr. Nishino- 2025 Diagnostic Pathologic Update #USCAP #pathology #PathX

[Janira Navarro @Janiranavarro]

Sinonasal biopsy showing necrosis and inflammation:

- GMS and PAS-F to rule out infection (invasive fungal sinusitis)
- IHC and EBER-ISH to rule out NK/T-cell lymphoma
- Recommend ANCA serology to rule out granulomatosis with polyangiitis

Dr. Nishino - 2025 Diagnostic Pathology Update #USCAP #pathology #PathX

[Andres Matoso @Andres_Matoso]

Testicular teratoma gone bad. Primitive looking somatic malignancy. See glomeruloid structures. PanCK should prompt WT1 staining. "Nephroblastoma arising from Teratoma" #GUpath #pathology

[Elizabeth Montgomery, MD @LizMontgomeryMD]

Traditional serrated adenoma (TSA) and tubular adenoma (TA) in the same biopsy cup. The nuclei in the TSA are much smaller and paler than those in the TA, even in the proliferation zones (the ectopic crypt formations).

[Dr. Yousef 🇵🇸 @yousef_ki1]

No words 💔
If you see these little angels, reply with 💔🇵🇸

[Dr. Yousef 🇵🇸 @yousef_ki1]

If you see this pic, reply with 🇵🇸 spread it 💔

[Felipe D'Almeida @FelipePatologia]

Giant collagen rosettes in a classic Low grade fibromyxoid sarcoma

#USCAP25 is coming!

[TheUnseenPath @TheUnseenPath_]

15 Hard Rules of Psychology and Life:

1.