Paris System 2.0

Official account for information regarding Paris System for Urinary Cytology version 2.0 | Supported by @cytopathology and @IACytology | curator @eva_wojcik

[Paris System 2.0 @ParisSystem2]

See poll:
1/ Negative for High Grade Urothelial Carcinoma
2/ Atypical Urothelial Cells
3/ Suspicious for High Grade Urothelial Carcinoma
4/ "Other" – Dysplastic Squamous Cells present

[Paris System 2.0 @ParisSystem2]

Anyone has cytology images of this type of HGUC? We are looking for 🦓 @eva_wojcik @cytopathology @IACytology

[Kamran Mirza MD PhD - کامران مرزا @KMirza]

Calling all #cytopathologists - help continue #ParisSystem2 be built!! @ParisSystem2 @edusqo @Sara_Jiang @DrFNA @cytopathology @aakasharmand @mtsiddi @sza_jhcyto

[Paris System 2.0 @ParisSystem2]

#ParisSystem2 @cytopathology @cytology2020 @NayarRitu @ZMaleki_cyto @sza_jhcyto @barkanga @aakasharmand @mtsiddi @pambuccian @Sara_Jiang @DianaEstherossi @EdCibas @Sinchita_Roy @lara_pijuan @AshishC97225686 @IACytology @Kristen__Atkins @DrFNA @PatMcIntireMD @MauroSaieg @iremessa

[Paris System 2.0 @ParisSystem2]

Bladder washing from a 56 year old man with intermittent dysuria and papillary lesion in the bladder shows numerous dysplastic squamous cells. Which diagnostic category of the Paris System should be applied? #ParisSystem (see below photos and poll)

[Paris System 2.0 @ParisSystem2]

See poll:
1/ Negative for High Grade Urothelial Carcinoma
2/ Atypical Urothelial Cells
3/ Suspicious for High Grade Urothelial Carcinoma
4/ "Other" – Dysplastic Squamous Cells present

[Paris System 2.0 @ParisSystem2]

Anyone has cytology images of this type of HGUC? We are looking for 🦓 @eva_wojcik @cytopathology @IACytology

[Farshid Siadat, MD, FRCPC @FSiadat]

Lipid-rich urothelial carcinoma. It is a rare and high grade variant with large lipoblast-like cells with cytoplasmic vacuoles indenting the nuclei.

#gupath #pathology #Bladdercancer

[Paris System 2.0 @ParisSystem2]

Excellent example - fibrovascular cores - no dx of LGUN without them!

[Zubair Baloch @aakasharmand]

@ParisSystem2 @eva_wojcik @barkanga @marcoslepe @twmarkc @pembeoltulu @PennPathLabMed @DiagnosticCyto @JASCJOURNAL @kriyer68 @sam_albadri

[Paris System 2.0 @ParisSystem2]

About 25%of HGUC can have some degree of squamous differentiation - malignant sq cells in urine. Also, there is primary Sq cell ca of bladder - associated with Schistosomiasis and/or any chronic irritation ex stones

[Deb Clapp (she/her/hers) @DebClapp1]

@dkurtycz @ParisSystem2 Can you briefly explain the image? Skin cancer in the bladder? I teach honors A&P and wish to show them this... but need help! Thank you!

[Paris System 2.0 @ParisSystem2]

1. HGUC (regardless N/C ratio (against rules of #ParisSystem)
2. SHGUC (you know is +, you can't ignore those cells but against #ParisSystem)
3. AUC (can't ignore those cells)
4. Negative for HG (degeneration not addressed in #ParisSystem )

[Paris System 2.0 @ParisSystem2]

N/C > 0.7 – the paramount of #ParisSystem for dx of HGUC. What to do with case like this (see below photo)? N/C<0.7 due to degeneration. F/U biopsy positive for CIS. Should we call: (see poll)

[Eva Wojcik, MD @eva_wojcik]

This is an opportunity to get involved!!! We are looking for good images for #ParisSystem2! @cytopathology @cytology2020 @NayarRitu @ZMaleki_cyto @sza_jhcyto @barkanga @aakasharmand @mtsiddi @pambuccian @Sara_Jiang @PatMcIntireMD @MauroSaieg @iremessa @DianaEstherossi

[Paris System 2.0 @ParisSystem2]

@dkurtycz @eva_wojcik @ParisSystem2

[dkurtycz @dkurtycz]

@ParisSystem2 squamous cell carcinoma of bladder

[Eva Wojcik, MD @eva_wojcik]

@Pathologists @MBDFlanaganMD @marenwhymd @dmlarsonpath1 @edusqo @EdCibas @RoseannIWu @Sinchita_Roy @lara_pijuan @GrazinaChatt @IACytology @AshishC97225686 @Kristen__Atkins

[Paris System 2.0 @ParisSystem2]

Work for the second edition of the #ParisSystem has started! Be a part of the @ParisSystem2 process by sharing your best images/cases with us (DM or tweet)

Your image(s) may be included (with permission and recognition of contributor) in the new edition!

[Paris System 2.0 @ParisSystem2]

Work for the second edition of the #ParisSystem has started! Be a part of the @ParisSystem2 process by sharing your best images/cases with us (DM or tweet)

Your image(s) may be included (with permission and recognition of contributor) in the new edition!