PaSER_Lab

PaSER Lab wants to help make proteomics fast, accurate and efficient through bioinformatics. 🇺🇦

[Matthias Mann Lab @labs_mann]

Our new preprint with #Bruker introduces synchro-PASEF, a highly efficient DIA scan mode that follows the ion cloud naturally. Fragments are directly linked to precursors via precursor slicing, generating pure, DDA-like ms/ms spectra.
https://t.co/1KNTk7t4hd

[bioRxiv @biorxivpreprint]

Synchro-PASEF allows precursor-specific fragment ion extraction and interference removal in data-independent acquisition https://t.co/FXpRIn5p4N #bioRxiv

[PaSER_Lab @PaserLab]

@YishaiLevin PaSER w/ TIMScore can help. TIMScore and CCS information for phosphopeptides is especially beneficial given the dominate neutral loss with poor b/y ion intensities.

[PaSER_Lab @PaserLab]

@DrCatherineB "skunskeen" for sunscreen and "misted you" for missed you. To cute to correct.

[PaSER_Lab @PaserLab]

@rhuttenhain @Stanford_MCP Congrats Ruth, will look forward to seeing your success.

[PaSER_Lab @PaserLab]

@UCDProteomics We agree wholeheartedly, with more and better capabilities on the horizon.

[PaSER_Lab @PaserLab]

@UCDProteomics @OliverMBernhar1 @VATVSLPR @NorSivaeb @nesvilab Hi Brett, You can use TIMS DIA-NN post acquisition on PaSER to search files again. This applies to dia-PASEF (Batch-DIA) and DDA data (Batch-DDA) and it is as fast or faster than real-time. TIMS DIA-NN is really tuned toward our dia-PASEF data type, especially the CCS values.