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Which of the following is the most likely diagnosis?
A. ALK positive histiocytosis
B. Erdheim-Chester disease
C. Extranodal Rosai-Dorfman disease
D. Inflammatory myofibroblastic tumor
E. Juvenile xanthogranuloma
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Image Quiz!
A 41 year old woman underwent a core needle biopsy for a 3 cm breast mass discovered on her first screening mammogram. The lesional spindle cells show the CD68 immunostaining pattern seen below; they are also positive for ALK and negative for SMA and desmin. (Cont.)
Mark your calendar for the Kameda Pathology Seminar, featuring Dr. Nat Pernick as a guest speaker, on December 25 at 18:00 JST! Participate online from anywhere or attend in person in Tokyo.
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View our new testimonials via the link in the comments!
We love hearing how our resources help people at all stages of their pathology careers. We welcome you to comment here or use the tutorial on the testimonials page to record your testimonial video.
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Case of the Month: A 32 year old woman with a clinical history of complex partial type seizures underwent a brain MRI, which showed a 2 cm solid cystic lesion without contrast enhancement in the left temporal lobe.
Although the lesion remained stable over a 1 year follow up, the patient underwent surgery due to an increased frequency of seizures. The lesion was completely removed; the patient is in good health with no evidence of recurrence 1 year after surgery. What's your diagnosis?