Assistant Professor @WashUMedicine | Antibody-based conditioning for stem cell transplant and its impact on host biology | #PhysicianScientist#NewPI#bmtsm
While I have mixed feelings about being back on Twitter, I have nothing but pride for this paper, my first mentee @AdityaYelamali 's first first author paper and my first paper as senior author.
Glad to have found a good home for this study in Blood ICT @BloodPortfolio
This article, recently published in Blood ICT, was accepted through our second look rapid response program. Check it out and consider giving your own research a second chance: https://t.co/0l0CbHudtc
Proud to amplify this study from Seung Kim’s lab about using antibody conditioning and JAK inhibition for allo-HSCT/tolerance induction for islet transplantation to treat NOD diabetes. Also grateful to have been able to write a short article about it with @Dipersiolab
Preventing graft re-JAK-tion: safer transplant conditioning enables murine islet allograft tolerance and #diabetes reversal: https://t.co/bGO42t2iHA
Stephen P. Persaud @PersaudSquad & John F. DiPersio @DiPersioLab@washumedicine provide a Commentary on Preksha Bhagchandani et al.: https://t.co/eI6GnQ0ajo
Curing autoimmune diabetes in mice!
Preksha Bhagchandani @prekshab17 et al. @StanfordMed present a clinically translatable, low toxicity conditioning regimen in combination with hematopoietic cell and islet transplantation that reverses established type 1 diabetes in mice: https://t.co/pwtgyGKK7M
The image: Histology of the recovered islet graft in diabetic mice that received allogeneic hematopoietic cell and islet transplantation shows intact B6 islets with few CD45+ immune cells 20 weeks after transplantation.