Phaneesh Bharadwaj

Nephrologist, Christian Medical College, Vellore, India

[Phaneesh Bharadwaj @PhaneeshBBS]

Just scratching the surface of AI. Taking baby steps today to prepare for the massive disruptions of tomorrow. 💡

Credit : Quote and Picture - Gemini AI)

[Phaneesh Bharadwaj @PhaneeshBBS]

Revisiting the past journey of nephrology in India with esteemed Dr. Chacko Korula Jacob at heritage lecture series, CMC

[Phaneesh Bharadwaj @PhaneeshBBS]

Transformative learning process begins with a "disorienting dilemma" - Jack Mezirow

[Phaneesh Bharadwaj @PhaneeshBBS]

Insightful workshop on critical appraisal of systematic review and the process of guideline development

[Phaneesh Bharadwaj @PhaneeshBBS]

Wonderful Interaction with the world renowned expert on post transplant infectious diseases - Dr Camille Kotton from Boston!

[Medical Info @Medicalinfo111]

Hepatorenal syndrome

[ChessBase India @ChessbaseIndia]

22nd September, 2024 is a red letter day for Indian Chess - this is one of the biggest moments in Indian Chess History. Team India wins Double Gold medals in the Chess Olympiad 2024! The Indian Open and Women's Team both secured Team Gold medals, with many more Individual Board medals to come.

Team India (Open) needed just a draw today for Team Gold, but they defeated Slovenia 3.5-0.5 anyway. Gukesh, Praggnanandhaa and Arjun scored wins on the top 3 boards, and Vidit had a long and fighting draw on board 4. The Indian Open Team secured first place with a whopping 21/22 Match points!

Team India (Women) had to win against Azerbaijan today, and they delivered with full force. Harika, Divya and Vantika won, while Vaishali drew her game. India defeated Azerbaijan 3.5-0.5! If Kazakhstan won against the USA today, there would've been tiebreaks involved - but that match ended in a draw. The Indian Women's Team secured first place with 19/22 match points!

A huge congratulations to all the players, coaches and the entire team involved. What a day!

Graphic: Anmol Bhargav
#chess #chessbaseindia #ChessOlympiad

[VVS Laxman @VVSLaxman281]

Dr Anagha Tulsi has performed over 1600 surgeries, including complex procedures like Arterial Switch Operations, Redo surgeries, AV canal repairs, Valve repairs, and both single and biventricular repairs at Sri Sathya Sai Sanjeevani International Centre for Child Heart Care and Research, Palwal, Haryana. This Totally Free of Cost Centre is dedicated to providing free Paediatric Cardiac   surgeries for children with congenital cardiac anomalies, performs over  2000 Pediatric cardiac surgeries and interventions every year.
She also focuses on training younger  surgeons, with two junior surgeons already performing independent surgeries and advancing in complexity under her guidance.
The entire team of Cardiologists, Anaesthetists, Nurses and allied staff at Sri Sathya Sai Sanjeevani International Centre for Child Heart Care and Research,Palwal work with the motto “Love All, Serve All.”

[Jasmine Sethi @JasmineNephro]

❤️‍🩹🫘How to prevent arrythmias in dialysis

@AJKDonline core curriculum

[Leonardo V. Riella @LVRiella]

With tremendous joy, I share that our patient who received a gene-edited pig kidney transplant was discharged home today after removal of his dialysis access. We hope that this is a first step that will bring hope to many patients waiting for a kidney transplant #xenotransplant

[Sanjeev Sethi @SethiRenalPath]

Finally. We figured out the dense deposits in dense deposit disease (DDD).

The answer is Apolipoprotein E.

You can stain for APOE & make the diagnosis of DDD in >80% cases. Without electron 🔬.

DDD was the reason I got into mass spectrometry 17 yrs ago. https://t.co/fQxitNbFYF

[Phaneesh Bharadwaj @PhaneeshBBS]

@normonatremia @kidney_boy 35mg/dl creat in a relatively stable patient - likely CKD >> AKI, which means the process was going on before the herbal supplements. It is more likely that she started taking those due to symptoms of CKD.
CIN picture in young female - autoimmune workup (esp sjogrens)

[Sundar Sankaran @sundar_s1955]

A man was asked to paint a boat.

He brought with him paint and brushes and began to paint the boat a bright red, as the owner asked him.

While painting, he noticed that there was a small hole in the hull, and quietly repaired it.

When finished painting, he received his money and left.

The next day, the owner of the boat came to the painter and presented him with a nice cheque, much higher than the payment for painting.

The painter was surprised and said "You've already paid me for painting the boat Sir!"

"But this is not for the paint job. It's for having repaired the hole in the boat."

"Ah! But it was such a small service... certainly it's not worth paying me such a high amount for something so insignificant."

"My dear friend, you do not understand. Let me tell you what happened.

When I asked you to paint the boat, I forgot to mention about the hole.

When the boat dried, my kids took the boat and went on a fishing trip.

They did not know that there was a hole. I was not at home at that time.

When I returned and noticed they had taken the boat, I was desperate because I remembered that the boat had a hole.

Imagine my relief and joy when I saw them returning from fishing.

Then, I examined the boat and found that you had repaired the hole! You see, now, what you did? You saved the life of my children! I do not have enough money to pay your 'small' good deed."

_So, no matter who, when or how. Just continue to help, sustain, wipe tears, listen attentively and carefully repair all the 'leaks' you find, because you never know when one is in need of us or when God holds a pleasant surprise for us to be helpful and important to someone_.

_You may have repaired numerous 'boat holes' along the way... of several people without realizing how many lives you've saved_.

So Keep up Good work ..

I want to thank Everyone who Repaired my Boat this year in every way like good wishes, thoughts, love, care & prayers... please continue to keep me in your thoughts and prayers 🙏

*Humanity is the best Religion* 🙏

Happy New Year 2024. Stay blessed with good health and peace.
🍾🍾🍾

सर्वे भवन्तु सुखिनः सर्वे सन्तु निरामया,
सर्वे भद्राणि पश्यन्तु मा कश्चिद् दुख भागभवेत।

🌹🙏🕉️🙏🌹

Message courtesy my friend
Pranab Pani
https://t.co/pwGxiZSntb

[Phaneesh Bharadwaj @PhaneeshBBS]

Gene therapy update - FDA approves Vertex/CRISPR for Sickle cell disease. Decision under review for transfusion-dependent beta thalassemia. More diseases expected to join the list in the future.
** https://t.co/6mrEh5CSUO
**Nephrology application- https://t.co/OBQzlX5aXt

#CRISPR

[Phaneesh Bharadwaj @PhaneeshBBS]

FDA has granted Fast Track designation to IMPT-514, a bispecific CD19/CD20-targeting chimeric antigen receptor (CAR) T-cell therapy for the treatment of active refractory lupus nephritis (LN) and systemic lupus erythematosus (SLE).

[Brian Orelli, PhD @BrianOrelli]

Woman on left and right are the same person. SLE before and after CD19 CAR-T treatment. 🤯

Due to wax and wane in SLE, it has been hard to prove drugs work. Much easier when you cure patients! No relapses for 8 patients 4-29 months followup. #ash23

[Phaneesh Bharadwaj @PhaneeshBBS]

@snamratarao Yes, lot of uncertainities but i felt this is the direction in which things may develop. Exciting times ahead!

[Phaneesh Bharadwaj @PhaneeshBBS]

My prediction of future - Precision medicine in management of IgA nephropathy.
Any comments?

[Phaneesh Bharadwaj @PhaneeshBBS]

@cavanaugh_do @GlassockJ I agree. This post is purely from an academic best scenario stand point!

[Phaneesh Bharadwaj @PhaneeshBBS]

@GlassockJ I also believe that UPCR and creatinine based eGFR are very rough estimates and future biomarkers to look at ongoing pathological process in an early and accurate manner will be change the way we manage all kidney diseases.

[Phaneesh Bharadwaj @PhaneeshBBS]

@GlassockJ I truly believe that with therapy targeting multiple points in the pathophysiological pathway, harm of general immunosupression with oral steroids/MMF will outweigh the benefit. Hence, precision medicine. But of course I may be wrong!

[Phaneesh Bharadwaj @PhaneeshBBS]

@abdelhamed012 Also, cost of these new drugs is an important factor to consider