PharmaHits

The most updated pharmacy clinical facts that will HIT straight into your mind..جرعات يومية من المعلومات والأسئلة الصيدلانية التي تختص بتطوير الجانب الإكلينيكي.

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من مبدأ زكاة العلم تعليمه ونشره، أنشأنا هذا الحساب الذي يختص بتطوير الجانب الإكلينيكي لكل طالب أو خريج صيدلة والذي سيساهم بطرح معلومة صيدلانية اكلينيكية أو أسئلة بشكل يومي. 🗒✨

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Correct answer: Amitryptyline.

The only approved medications for OCD are: Clomipramine, Fluxetine, Sertraline, Paroxetine, and Fluvoxamine due to their potent 5-HT reuptake inhibition which is important for the antiobsessional effect.

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Which one of these medications is *NOT* FDA approved for the management of OCD?

OCD: Obsessive Compulsive Disorder

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Correct answer —> Betrixaban

Betrixaban is the only NOAC approved for VTE prophylaxis. However, Rivaroxaban and Apixaban are approved for VTE prophylaxis after knee and hip surgeries only.

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Which of these NOAC’s is approved for VTE prophylaxis?

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Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of

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Correct answer—> 2 NRTI’s + NNRTI’s

PI is contraindicated with rifampin.

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Women newly diagnosed with HIV that requires urgent starting ART due to low CD4 count, she takes the 4 anti-TB medications for pulmonary TB, so the preffered ART regimen is?

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Correct answer-> Initiate Vancomycin 👏🏼

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An 82-year-old patient with documented pneumococcal pneumonia is unresponsive to 3 days of ceftriaxone. Gram-positive diplococci are present. Which action is most appropriate to take?

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Correct answer is B
Dofetilide, ibutilide, amiodarone, and sotalol are class III antiarrhythmic agents. Class III agents prolong the refractory period and myocardial action potential and are used to treat ventricular arrhythmias.

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Which of the following drugs is a class III antiarrhythmic agent that is effective in the acute management of atrial fibrillation or atrial flutter of recent onset?

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Correct answer is D
Betamethasone is about 25 times as po- tent as hydrocortisone, 5 to 6 times as potent as prednisone, 4 to 6 times as potent as triam- cinolone, and about 30 times as potent as cor- tisone.

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Which one of glucocorticoids, has the greatest anti-inflammatory potency when administered systemically?

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Penicillins and cephalosporins should NOT be given via intraventricular route because they cause significant neurotoxicity which may lead to serious seizures.

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Correct answer is B
At doses of 2 to 5 mcg/kg/min, it increases renal blood flow through its dopaminergic effects. At doses of 5 to 10 mcg/kg/min, it increases cardiac output through its B- adrenergic stimulating effect. At doses of 10 to 20 mcg/kg/min, it increases PVR

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If treating a patient with HF, which of the following dosages of dopamine would be used to elicit its positive inotropic effects?

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Coorect answer is minoxidil—-> Reflex tachycardia is commonly seen with the use of peripheral vasodilators such as minoxidil (Loniten) and hydralazine (Apresoline).

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Reflex tachycardia is an adverse effect most likely to be associated with the use of which of the following drugs

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The use of 3rd gen cephalosporin , Clindamycin, FQ, Carbapenem is considered a risk factor for developing C. diff infection.