Philip

[Physio Meets Science @PhysioMeScience]

Just published in European Spine Journal 🔥

Incidence of and risk factors for lumbar disc herniation with radiculopathy in adults: a systematic review

https://t.co/x5i5MBSLpN

Illustration: https://t.co/bqlNfXGZ55

[Physio Meets Science @PhysioMeScience]

Exercise as a therapeutic tool in age-related frailty and cardiovascular disease: challenges and strategies

https://t.co/hsbVdjkDhV

[Pascal Blanché @pascalblanche]

Syd Mead.

[James Noake @DrJN_SportsMed]

Thread alert 🚨🚨🚨

Ankle inversion injuries don't just result in lateral ligament sprains....

...there are plenty of other injuries to bear in mind when you assess, both acutely & further down the line

[OrthoEvidence @OrthoEvidence]

💊Duloxetine for Hip & Knee Osteoarthritis: A Systematic Review & Meta-Analysis
An OE Original

Depression...anxiety...osteoarthritis?

Duloxetine is commonly used as an antidepressant but has also been utilized to manage pain.

Can it effectively manage pain from hip & knee osteoarthritis?

🏗️METHODS
We searched MEDLINE, EMBASE, Cochrane CENTRAL, and the OE MIND database for randomized controlled trials (RCTs) comparing:

1⃣ Duloxetine
2⃣ Control (ex. placebo; usual care)

We performed a risk of bias assessment and utilized the grade approach to assess the quality of the evidence.

Outcomes of interest included:
- Pain (measured with the Brief Pain Inventory [BPI] & Visual Analog Scale [VAS])
- Western Ontario and McMaster Universities Arthritis Index (WOMAC)
- Adverse events

🔎RESULTS
9 RCTs with a total of 2,431 hip/knee osteoarthritis patients were included!

The risk of bias was low for most of the studies!

BPI Average Pain
Pooled BPI average pain scores after 7-8 & 12 weeks of treatment were significantly in favour of the duloxetine group!

VAS Pain
Pooled VAS pain scores after 7-8 weeks of treatment were also significantly in favour of the duloxetine group!

WOMAC
Pooled WOMAC total scores after 7-8 & 12 weeks of treatment were significantly in favour of the duloxetine group!

All WOMAC subscores (pain; function; stiffness) were also in favour of duloxetine at both time points!

Adverse Events (AEs)
The risk of treatment-emergent AEs, nausea, dizziness, and somnolence were all significantly higher in the duloxetine group.

✅INTERPRETATION
Duloxetine appears to be an effective treatment for improving pain and function for patients with hip or knee osteoarthritis.

However, a higher risk of minor adverse events such as nausea or dizziness may accompany the benefits!

[James McCormack @Flawless_Physio]

Progressive Achilles Tendon Loading.
Thanks to @joshrbaxter et al.

[Philip @Philphyy]

#SuperbetChessClassic for everyone. Guilty pleasure opening line?

[Physio Meets Science @PhysioMeScience]

Nonoperative treatment of lateral epicondylitis: a systematic review and meta-analysis

https://t.co/GrLWFhx2t7

[Brad Schoenfeld, PhD @BradSchoenfeld]

For those interested in understanding the mechanistic underpinnings of muscle hypertrophy, our review provides what I believe is the most comprehensive discussion on the topic, as well as highlighting how much is yet to be determined https://t.co/1mODf9LLFH

[Physio Meets Science @PhysioMeScience]

Not All Pain is Created Equal: Basic Definitions and Diagnostic Work-Up

https://t.co/dhlvHXUN6F

[Philip @Philphyy]

@PeterDaBest123 dude what is this

[Jozo Grgic @Jozo_Grgic]

The Effects of Low-Load vs. High-Load Resistance Training on Muscle Fiber Hypertrophy: A Meta-Analysis

https://t.co/i4dRndbprJ

[Federico Italiano @FedeItaliano76]

Sci-fi environments by Nick Stathopoulos—a few more here https://t.co/FkmAxYuDXI

[Physio Meets Science @PhysioMeScience]

Placebo effect in the management of chronic pain

👀👀👇👇

@GiacomoRoss86

https://t.co/pyujUoiCrs

[Physio Meets Science @PhysioMeScience]

Which Interventions Enhance Pain Self-efficacy in People With Chronic Musculoskeletal Pain? A Systematic Review With Meta-analysis of Randomized Controlled Trials, Including Over 12 000 Participants

👀👀👇👇

https://t.co/b62fqYDiwa

[Humanoid History @HumanoidHistory]

Syd Mead concept art pictures an entertainment zone in a proposed development in Seoul, South Korea, 1996.

[PAIN Journal @PAINthejournal]

For the first time since 1979, IASP is introducing a revised definition of #pain. View the definition and accompanying notes in #PAINJournal. #FreeAccess https://t.co/RoSfFhk3Sp

[Dr Jon Sharpe FRCR @DrJonSharpe]

This is why we use MRI in patients with suspected scaphoid fractures who remain symptomatic - despite apparently normal radiographs. #FOAMed #FOAMrad #orthotwitter

[Jozo Grgic @Jozo_Grgic]

Can Hip Joint Position affect Quadriceps Muscle Responses during Knee Extension Exercise?

https://t.co/uN6LmUlbPe