Matthias Piesche

Scientist @ UCM. @DanaFarber/@HarvardMed Alumni. Passionate about #cancer immunology, #immunotherapy & what the gut #microbiome has to do with it

[Matthias Piesche @PiescheLab]

What I learned as student: #Polymerases need a DNA template to make more of it... WRONG WRONG WRONG

#DRT3 doesn't need it, can do it by using its own structure as template.

Science is beautiful and full of surprises

https://t.co/jRQ33dQx7U
Paper: https://t.co/JGWiAzK7VY

[Matthias Piesche @PiescheLab]

Important 2 know the difference between correlation & causation. Maybe someone should also analyse the connection of breathing & autism. Its worse: 100% of children with autism were breathing air from birth to diagnosis with a concentration of 21% O2 and 78% N2

[Simon Maechling @simonmaechling]

This “study” looks serious.
It has an abstract, authors, even affiliations.
But read it carefully - it’s pure satire.

And it brilliantly exposes one of the biggest flaws in bad science: confusing correlation with causation.

“Over 90% of autistic children consumed breast milk or formula milk.”

Sounds alarming - until you realize:
over 90% of all children consume breast or formula milk.

That’s not a discovery.
That’s basic biology.

The fake authors - I. M. Amoron, U. R. Gullible, N. O. Control - mock real-world habits of pseudoscientific papers: no controls, no confounders, no significance, but big claims.

Exactly how misinformation about vaccines, food, or chemicals spreads.

And then there’s this gem: 👇
A “Letter to the Editor” mourning the loss of a control group that only consumed saline. “We are beside ourselves.”

Dark humor - but also truth.
You can’t always test nutrition or medicine by comparing it to… nothing.

Both jokes share one message:
Bad science isn’t funny when it drives public fear.

It’s what happens when people demand “gold-standard” trials without understanding how science actually works.

The moral? You can always find a “correlation” if you look hard enough.

Correlation is easy.
Causation is hard - and that’s why science demands evidence, not coincidence.

So next time you see a viral “study” that blames something ordinary for a complex condition…
ask two questions:

Was there a control group?
Did they prove causation - or just correlation?

If not, congratulations - you just passed your first course in critical thinking.

Humor can be a powerful teaching tool.
These parodies remind us that critical thinking isn’t optional - it’s survival.

Because behind every “funny” fake study, there’s a real one being misused by someone who doesn’t get the joke.🧠

Thank you @IntegralAnswers for this example.

[Matthias Piesche @PiescheLab]

The bad bad #mRNA #vaccine against #cancer works. How can that be? Isnt it the devil from the COVID vax? Maybe reading real scientific studies instead of listening to all the Google educated "scientists" could explain it. Thanks @EricTopol 4 showing this publication. Encouraging

[Eric Topol @EricTopol]

How do mRNA vaccines help fight cancer?
A @nature publication today tells the story, one with big implications, as reviewed here @MDAndersonNews
@StevenLin_MDPhD @adam_grippin
https://t.co/J0OvNP1Oc4

[Matthias Piesche @PiescheLab]

Been through some storms, but hard work has paid off. Thanks @ucatolicamaule @facmedicinaucm

With new energy back what I love...how to manipulate the immune system to fight diseases.

#promotion #fullprofessor #immunotherapy #cancer #scienceworks

[Matthias Piesche @PiescheLab]

Outch Twitter.

https://t.co/PZOpc3rrGb

[Matthias Piesche @PiescheLab]

Someone should tell the current administration, @realDonaldTrump

"Over time, the U.S. military would come to see climate change as both a threat in itself and a threat multiplier for national security."

Science works, b***

[The Conversation U.S. @ConversationUS]

The US military has cared about climate change since the dawn of the Cold War – for good reason https://t.co/b67fGoI54K

[Matthias Piesche @PiescheLab]

El plazo de entrega se ha ampliado hasta el 14 de septiembre de 2024. Escríbeme a: [email protected]

@ucatolicamaule

#ingenieriaenbiotecnologia #bioquimica #biologia #inmunologia #tecnologiamedica #quimicayfarmacia

[Matthias Piesche @PiescheLab]

¿Estás interesado en trabajar en un laboratorio innovador en inmunoterapia contra el #cáncer y biomarcadores de cáncer? Estamos contratando!! Correo electrónico a [email protected]

@ucatolicamaule
#ingenieriaenbiotecnologia #bioquimica #biologia #tecnologiamedica #quimicayfarmacia

[Matthias Piesche @PiescheLab]

@farid__jalali Have you also looked into other cytokines? Especially TGFb? Fluvo & Niclo can suppress it and we hypothesized that TGFb play a prominent role in severe C19 and might also be important in LC

[Matthias Piesche @PiescheLab]

Assume that I can...and that I will

#WorldDownSyndromeDay
#EndTheStereotype

[Global Down Syndrome Foundation @GDSFoundation]

“Assume That I Can” awareness video is taking the internet by storm! @madisontevlin delivers ANOTHER “must see” performance! GLOBAL is a proud sponsor of the CoorDown international awareness campaign video.
#assumethatican #WDSd24 #WorldDownSyndromeDay #EndTheStereotypes

[Matthias Piesche @PiescheLab]

@ArmchairResist No I don't have any. But I think integrative can be important. Eg, a healthy diet and exercise

[Matthias Piesche @PiescheLab]

Reduce sugar intake but don't replace it with #artificial #sweeteners. They alter your gut #microbiome for the worse, increasing the chance of chronic diseases and others https://t.co/Hdw9gdXQHR #artificialsweeteners #stevia #splenda #aspartame #sucralose #saccharin

[Matthias Piesche @PiescheLab]

I would also add: risks failure/bankruptcy of the company (especially if it is a small one)

[Matthias Piesche @PiescheLab]

Sounds familiar? https://t.co/w9I0cJvTUd

[Matthias Piesche @PiescheLab]

The #social #network of proteins - very interesting research w future impact in health and disease https://t.co/QH2afS1Qrf
Paper: https://t.co/WgcJu6nZUD

[Matthias Piesche @PiescheLab]

@StuffedNation @Forbes Your article doesnt say anything about the pot. negative effect of artif. sweeteners on the gut microbiome. I wouldnt call them save. More & more studies show the importance of a healthy microbiome, eg, cancer, autoimmune diseases, aging, etc. A disruption could be detrimental

[Matthias Piesche @PiescheLab]

Doesn't mean they're autom. the best, just have better opport. @ their early career. There was a paper few years ago demonstrating that

Early-career factors largely determine the future impact of prominent researchers: evidence across 8 scientific fields https://t.co/Iq9WqGKl07

[Matthias Piesche @PiescheLab]

Bh3 profiling could predict in real time which drug/combo drug will likely benefit the patient without knowing the genetics (last 2 links)

Study explains why many #cancer drugs fail during #clinicaltrials https://t.co/cEfPoIV1sd

https://t.co/pFZdDBVKpp

https://t.co/aTiEGJHbZU

[Matthias Piesche @PiescheLab]

Postdocs: highly educated, working horses of innovative discoveries, low salary, long working hours, no job security - find the problem

Falling behind: #postdocs in their thirties tire of putting life on hold https://t.co/W91phhpFvG