Satish

Senior Investigator @Vitalant | Professor @UCSF | #virologist and musician focused on RNA virus eradication and analog #synthesizers

[Satish @PillaiLab]

New work from Dr. Li Du in our group revealing that HIV shields itself from innate immunity by inducing and hijacking a host microRNA:

[Molecular Therapy Family of Journals @MolTherapy]

microRNA-422a Promotes HIV Replication and Innate Immune Evasion by Targeting MECP2 https://t.co/5g9ltuORzf #MTNA

[Satish @PillaiLab]

@padminipillai @VirusesImmunity @maria_tokuyama Dad was a true MangoMaster - I miss him force-feeding me mangoes when I least expected it. :(

[Satish @PillaiLab]

Thanks @ChemicalBiology! Our lab is already investigating #glycosylation + #SARSCoV2 infectivity + modulation by #Galectins. Posting more details soon!

[Laura Kiessling @ChemicalBiology]

These findings suggest that the glycosylation state of the virus should influence the effects of the lectin. Human Galectin-9 Potently Enhances SARS-CoV-2 Replication and Inflammation in Airway Epithelial Cells | bioRxiv #glycotime https://t.co/EA915m752D

[Eric Topol @EricTopol]

What did we learn from giving people #SARSCoV2?
The 1st challenge study report 🆕 @NatureMedicine
https://t.co/7MpHwIn7qC
—Viral load is not correlated w/ symptoms
—Shedding occurs at high levels irrespective of symptoms
—Rapid antigen tests are extremely useful
and much more

[Prof. Shane Crotty @profshanecrotty]

We just completed an article reviewing protective immunity to COVID-19. Hopefully it is a helpful summary and framework for the field moving forward, considering correlates and mechanisms.
https://t.co/4Y5oMu4n9P

[Satish @PillaiLab]

Excited to share this sweet new preprint from Dr. @DULI04769643 in our group revealing that the human sugar-binding protein #Galectin9 potently enhances #SARSCoV2 replication and inflammation in airway epithelial cells #COVID19 @Vitalant @UCSF https://t.co/cujf2dwq9N

[Prof. Shane Crotty @profshanecrotty]

Our new pre-print posted. We compare immune memory to Moderna, Pfizer, J&J, and Novavax COVID-19 vaccines head-to-head. T cells, B cells, and antibody. We think this is the most comprehensive immunological evaluation of these four different vaccines. 1/17
https://t.co/jHeQk41jHX

[John Greenland @jrgreenland]

New #COVID19 mechanism: Gal-9 helps the virus attach to airways. https://t.co/WhckPfe25A

[Ben Rothenberg @BenRothenberg]

Here are Rafael Nadal’s full answers on the Novak Djokovic situation, which Nadal clearly thinks Djokovic created for himself.

Nadal has consistently backed the science of vaccines during the pandemic, so this is a pretty consistent line of answering for him.

[Satish @PillaiLab]

Hi All - very exciting opportunity to work with my sister @padminipillai and crew in the Langer Lab @MIT on nanotherapies for cancer!:

[Joshua Roebke, mostly living under clearer skies. @joshua_roebke]

👋 I am an award-winning science writer and I just published an article about how to “deconsecrate” science writing. You should read it! It’s fun!

I also want to share some experiences I’ve had freelancing to help my fellow writers. 🧵 1/n

https://t.co/ri2BYPFcsi

[Satish @PillaiLab]

@KurianLab Incredibly important to share our successes, struggles, and failures as scientists to provide a real picture and strengthen our community. Rock on @KurianLab!

[Satish @PillaiLab]

@KurianLab Thank you so much for sharing this sentiment! I hear ya loud and clear - have felt the same way this past year (and incidentally also just took a critical science-free vacation that recharged the batteries!).

[Cell Reports @CellReports]

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins https://t.co/jNMSSw0d5y

[Lorenzo Morotti @Enzomorotti]

UPDATE: Black bear was steered thru yards to the base of Mt. Tam safely w/o use of tranq. It put a hole in a fence on the way out. Bear was a 150/200 lb adolescent (1-2 yrs old) male who left home to set up his own territory. He took a wrong turn into @SanAnselmoCA and was scared

[Satish @PillaiLab]

Happy #InternationalWomensDay everyone! Sharing this beautiful piece from my sis @padminipillai about our amazing and inspiring Mom!!!