Chemistry lab at the University of Oregon. Focused on molecular recognition, physical organic chemistry, and chemical biology of reactive S and Se species.
Excited to share our Chem Rev on the bioinorganic chemistry of persulfides! Includes biological chemistry, bioinorganic models, inorganic systems, & isolable S/Se compounds.
A huge congrats to Keyan (@keyanl10) for this heroic undertaking! https://t.co/jBmK3r7RQe
Do ‘gasotransmitters’ need to be gases? Andy makes the case in Redox Biology for Protic Small Molecule Bioregulators (PSMBs): a cross-cutting class of small molecules where protonation states impact biological speciation, permeability, & action. @agdavis98 https://t.co/VRCFADQGu3
Curious about the impacts of Lewis acids on persulfide & thioselenide chemistry? Check out Keyan & Addison’s paper using isolated ZnSSR & ZnSeSR complexes to directly study reactivity. Lots of insights from 77Se NMR & XRD! @keyanl10@angew_chem https://t.co/lpKjos2902
Hydrogen cyanide (HCN) is the newest gasotransmitter & a key protic small molecule bioregulator. We developed a platform approach to develop & deploy biocompatible responsive chemical tools for HCN delivery. Check out Mike's paper in @angew_chem! https://t.co/317Xe9GFdw
New Chem Commun paper on Cys-activated H2Se delivery from isoselenocyanates. Includes mechanistic insights, solution characterization, and cell imaging. Great work Reis, Keyan, Christopher, Arman, Turner, & Kaylin! https://t.co/WdqlV465mR
New ACS Chem Biol paper out: No H2S needed - We show that an increasingly common approach for H2S detection actual reports on thiols and esterases. Nice work Haley (@hsmith922), Aleanna, Christopher, & Ally sorting out the chemistry of this system! https://t.co/JBkpNoUktH
Congratulations to the 2025 recipients of the Chemistry and Biochemistry Graduate Student Teaching Awards: Sylvia Kennerly, Marie Kerns, Natalie Lakanen, Keyan Li, Rohan Myers, and Dario Nunez! https://t.co/PyyTO7ehqF
Check out our @InorgChem paper on Fe-NO formation from Fe(II) w/ SSNO(-) & SNO(-)! New insights into metal nitrosyl & reactive sulfur species formation from small S/N hybrid molecules. Great work Keyan (@Keyanl10), Juan, and George! https://t.co/0MvM5xqtX4
New @InorgChem paper: Mo/W-CO complexes + S₈ → COS! Highlights links between CO & reactive S species (Se behaves differently!) Initial 2023 @ChemRxiv preprint, now w COS quantification & new insights. Great work Toby, Haley & Keyan! @hsmith922 @keyanl10 https://t.co/stNGLxlWcM
Check out Shiva’s @ChemicalScience paper on using in situ ReactIR to measure host-guest binding affinities across hydrogen and halogen-bonding #supramolecular systems. Can be used w/ host or guest vibrations to measure Ka values. Great work @ShivaMoaven!
https://t.co/WXVyUBuO0K
Honored to receive the UO CAS Collegiate Faculty Award! Thanks @uocas for this recognition, and for recognizing the research contributions, creativity, and innovation from @PluthGroup members!
https://t.co/1mLhIamVE4