Pragmatic trials in primary care research. Optimizing use of existing therapeutics. Measuring what matters for patients & providers. Dr. Scott Garrison MD, UofA
CIHR has supported many #ClinicalTrials to improve medical treatment in Canada.
A study led by Dr. Scott Garrison @UAlberta evaluated how available blood pressure medication may reduce the risk of heart attack or stroke.
Details: https://t.co/zjRR0Nsf31
Latest just published simulation confirms large effect overestimates of trials stopped early for benefit. Trials typical of those stopped early for benefit overestimate relative risk reduction by 50%; need 250 events to ensure minimal overestimates. https://t.co/PDV4OMbyJU