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Rebecca Fitzgerald
@RC_Fitzgerald
Researching early cancer detection solutions. With 4 boys and ageing parents I know about balancing academic and private live. Keen to encourage aspiring GIs.
Cambridge
Joined September 2014
24
Following
317
Followers
75
Posts
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
Main points: - do surveillance well - get your pathologist to do p53 IHC - Cytopsonge might save on endoscopy. Watch that space!
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanForgacs
don't worry Ian, it is only your oesophagus that is at risk if you have heartburn!
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
Just to emphasize that ablation is for dysplasia and not for everyone.
#FGDebate
Who to follow
Rebecca Fitzgerald Lab
@RFitzgerald_lab
We are based at the Early Cancer Institute, University of Cambridge. Our lab goal is to improve outcomes for cancer of the oesophagus through earlier diagnosis.
Early Cancer Institute, University of Cambridge
@EarlyCancerCam
Updates from the Early Cancer Institute at the University of Cambridge. All views & opinions expressed are not necessarily those of the Early Cancer Institute.
CRUK Cambridge Institute
@CRUK_CI
We are a world-leading cancer research institute dedicated to improving patient lives through discovery science. Core funded by @CR_UK, part of @Cambridge_Uni.
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
This is where the
#Cytosponge
could also be advantageous. Just need to determine biomarkers for surveillance but p53 looks good
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanForgacs
Because of sampling bias and late dysplasia sadly I do think we need lots of biopsies
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@FrontGastro_BMJ
Good question. Patients with confirmed dysplasia. Does have side effects -EG stricture and costs so not for all
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@saragreensara
Interesting but needs more data. Not ready for routine use yet.
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
#FGDebate
https://t.co/U6RznzZpGZ
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanARowe
@FrontGastro_BMJ
@IanForgacs
Agree. This is still research territory. Clinical surveillance needs careful white light OGD + path
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanARowe
@FrontGastro_BMJ
@IanForgacs
Agree. This is still research territory. Clinical surveillance needs careful white light OGD + path
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
Advanced imaging needs skilled endoscopists to interpret the images, which can have very subtle changes
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanForgacs
Good data support careful endoscopists using white light is generally the best way.
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@CharlieMuz
@IanForgacs
@FrontGastro_BMJ
Good point.
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@FrontGastro_BMJ
@IanForgacs
I think dedicated lists and endoscopists as routine, centralization for long segment and dysplasia
#FGDebate
RC_Fitzgerald
Β retweeted
Frontline Gastro
@FrontGastro_BMJ
over 10 years ago
@IanForgacs
Is this the case of centralisation the Dutch have advocated?
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanForgacs
Yes I think so if it's worth doing it needs doing well!
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
Great thing about
#Cytosponge
is can use it in primary care, little sampling bias and objective biomarker to diagnose
#Barretts
#FGDebate
RC_Fitzgerald
Β retweeted
Frontline Gastro
@FrontGastro_BMJ
over 10 years ago
@RC_Fitzgerald
@IanForgacs
Here is the link to the
@BritSocGastro
guidelines on this http://t.co/iZz90Pf8hl
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@CharlieMuz
@IanForgacs
I agree non-endoscopic methods need to take over diagnosis and surveillance?
#FGDebate
Rebecca Fitzgerald
@RC_Fitzgerald
over 10 years ago
@IanForgacs
Thanks! We really tried to make the guidelines practical & user-friendly. Check them out on BSG website
#FGDebate
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