@v7kakarot@TheKaiden123 no he got angry at dave because it was an insult to his religion, which compounded on him going cold turkey without sopor slime. then he's finally pushed over the edge after coming into contact with lil'cal the juju that contains a future/alternate him's soul.
@v7kakarot@TheKaiden123 as others already pointed out, gamzee was narratively doomed from even before we were introduced to him. after learning what was pre-destined to happen to him, he... well, to say he went insane is like saying the joker went insane. it's a little complicated.