Rolando J. Acosta

Biostatistician at @Regeneron
Biostatistics, PhD, @HarvardU
Comp. Math., @UPRH
🇵🇷 Home, 🇩🇴 2da patria

[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

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[Rolando J. Acosta @RJANunez]

🚨 New paper alert 🚨

Peripheral Blood Cells as Prognostic Markers in Patients with Advanced NSCLC Treated with Cemiplimab (mono or +chemo)

Key Findings:
⬆️ NLR & Monocytes = worse survival
⬆️ Eosinophils = better survival

Read about our work: https://t.co/1YyFRwanMD

[Rafael Irizarry @rafalab]

Biologists, stop putting UMAP plots in your papers!

UMAP is a powerful tool for exploratory data analysis, but without a clear understanding of how it works, it can easily lead to confusion and misinterpretation.

Link to @simplystats blogpost below.

[Gary Collins @GSCollins]

NEW PAPER out today in @BMJ_latest TRIPOD+AI: reporting recommendations for studies developing or validating prediction models for use in healthcare that use #machinelearning methods

https://t.co/ed9oiB1MVG

#ArtificialIntelligence #AIstandards #OpenAccess

Please share 🙏

[Rafael Irizarry @rafalab]

The latest version of the excessmort package is now on CRAN. With just a few lines of code, you can create informative plots like the one below.

A recent paper shows that our method for estimating excess mortality outperforms the widely used WHO method: https://t.co/pp2F9tkBeU

[Gabriel Loewinger @GLoewinger]

Want to test the effect of events/behavior at every trial time-point in photometry analyses?? Pre-print w/ @erjiastats, @LovingerDavid, @fpereira: "A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments" https://t.co/7vsdkdkncF. 1/13

[Rolando J. Acosta @RJANunez]

I’m presenting at the 6th Annual Digital Biomarkers in Clinical Trials Summit next week. Join us to learn more about #digitalhealth and #digitalbiomarkers in #clinicaltrials.

More info here: https://t.co/kbBwkx3tah

[Edward Kennedy @edwardhkennedy]

This paper was really fun!

We give new methods for estimating bounds on the avg treatment effect -- here trt is confounded, but you have an instrumental variable. Super common setting in practice

The bounds are non-smooth, so std nonparametric efficiency theory isn't applicable