Léa Rochet

Chemistry PhD student at @UCL within the @Etntact research project

[Albada Lab @NanoChemBiol]

Modular Semisynthetic Approach to Generate T Cell-Dependent Bispecific Constructs from Recombinant IgG1 Antibodies | Bioconjugate Chemistry https://t.co/C168yC5dCc

[Fabien Thoreau @FabienThoreau]

Check out this open PhD position in our team!!

✅ Very Cool subject
✅ Very Cool team
✅ Very Cool working facilities

"What else !?"

Don't hesitate to get it touch and candidate!

@SebastienPapot
@IC2MP

[Baker Group @BakerGroupUCL]

🚨PhD Opportunity:🚨

Come and join us and @VijayChudasama_ at UCL Chemistry investigating new chemical methods for empowering antibody conjugates partnered with @GSK! 🧪

See https://t.co/qiPX93pOmV for more info:

https://t.co/jul9fxS07u

[Vijay Chudasama @VijayChudasama_]

Very proud to share our latest collaborative paper with @BakerGroupUCL where we disclose the chemo- and regio-selective differential modification of cysteines on a native antibody; a first-in-class strategy! Led by the fantastic @yapyongyi! @UCLChemistry
https://t.co/ssC308zyk1

[Angewandte Chemie @angew_chem]

Macrocyclic Dual-Locked "Turn-On" Drug for Selective and Traceless Release in Cancer Cells (Tanja Weil and co-workers) @WeilTanja @Seah_Ling @DominikSchauen1 @VijayChudasama_ @RochetLea @J_A_S_Coelho @Lab_DavidNg #openaccess https://t.co/FlYYNd7Llj

[Tanja Weil @WeilTanja]

We report a dual-lock approach to embed small molecule drugs in cyclic structure, for selective & traceless release in cancer cells.
Congrats to @DominikSchauen1, @Seah_Ling & our collaborators @VijayChudasama_ @J_A_S_Coelho!
https://t.co/ItO71CIEwi

[TACT-ETN @EtnTact]

🌟 Happy International Women's Rights Day! 🌟
Today, as we celebrate the incredible achievements of women worldwide, let's also reflect on some important numbers with the different TACT members.
#IWD2024 #WomenInSTEM

[Léa Rochet @RochetLea]

@claudele_ Congratulations!! 🥳

[Wagner/Chaubet group - BFC @BFC_UMR7199]

It's @LorenzoTurelli_ viva! 🇮🇹
Because it's confidential, we had to use our mad Photoshop skills to hide his fantastic work. Can you identify which parts have been edited?

[Léa Rochet @RochetLea]

@ChaubetGuilhem @EtnTact @IKoutsopetras @Maraniach @yagmurersy @MSCActions It was a pleasure/honour to work on this for my secondment 😁

[TACT-ETN @EtnTact]

Congratulations @ChaubetGuilhem and @IKoutsopetras for a great work developing the Ugi reaction for site-selective protein modification! 👏 A great TACT collaboration too involving the ESRs @Maraniach from LSMBO and @yagmurersy from TUM! @MSCActions

[Chaubet Guilhem @ChaubetGuilhem]

"𝑻𝒉𝒆 𝑼𝒈𝒊 𝑺𝒕𝒓𝒊𝒌𝒆𝒔 𝑩𝒂𝒄𝒌"
Extremely proud to report our follow-up study on the application of the Ugi reaction to protein conjugation, this time with ✨𝐬𝐢𝐭𝐞-𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐜𝐨𝐧𝐝𝐢𝐭𝐢𝐨𝐧𝐬✨
https://t.co/BR6MEBsv43

[Léa Rochet @RochetLea]

Congratulations to my dear TACT colleagues @Maraniach and @Loic_H10 for the completion of their PhD!! 🥳

[TACT-ETN @EtnTact]

Let us introduce you to the first two Doctors of the TACT project: @Loic_H10 and @Maraniach!
Congratulations to both for their hard work and impressive accomplishments, concluded with an outstanding defense. We wish them all the best for the future! @MSCActions #PhinisheD #TACT

[Irene Shajan @IreneShajan]

Extremely happy to have this one out! Huge thanks to @baukevon, Floris and @VijayChudasama_ . Thanks and congratulations to you @RochetLea on this. We finally made it. Thank you @EtnTact for this opportunity- almost half the consortium contributed to this work!

[Vijay Chudasama @VijayChudasama_]

@NanoChemBiol @IreneShajan @ORC_PhDs Likewise! It was really great to work with lots of @EtnTact people on this, but especially with yourself, Floris, Chris and (of course) @RochetLea + @IreneShajan. Congratulations all!

[Léa Rochet @RochetLea]

Super happy to see this paper out! Thanks and congrats @IreneShajan @NanoChemBiol @VijayChudasama_ for the great collaboration 😁

[Albada Lab @NanoChemBiol]

I could not have been more happy with the outcome of this work! Congratulations to @IreneShajan @ORC_PhDs @VijayChudasama_ and many others!

Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry | Bioconjugate Chemistry https://t.co/f3DQULo3ZM

[TACT-ETN @EtnTact]

Happy Movember!👨‍🦰
To raise awereness for men's mental health, suicide prevention, prostate cancer and testicular cancer, TACT wanted to tell you something...
#Movember

[Léa Rochet @RochetLea]

@VijayChudasama_ Huge thanks to the other authors who enabled to go deeper in the study of those pyridazinediones, @IKoutsopetras, Phyllida Britton, @DKBucar, @ThanasiIoanna, @spearsyrick. Special mention to @dr_mike_porter and Abil Aliev for the DFT and NMR studies!

[Léa Rochet @RochetLea]

Very happy to finally have this paper out on one of my main PhD work! Huge thanks to everyone who contributed esp Calise Bahou @jono_wojfor for their precious help in developing this study on tuneable pyridazinedione for cysteine modification! Very grateful to @VijayChudasama_ -

[Vijay Chudasama @VijayChudasama_]

Huge congratulations to @RochetLea on her work on the use of pyridazinediones for tuneable & reversible covalent cysteine modification, a highly collaborative project with @BakerGroupUCL @dr_mike_porter @DKBucar Molly Stevens & Abil Aliev, plus many more! https://t.co/sA9J2GyvcC

[Léa Rochet @RochetLea]

Thanks @VijayChudasama_ for the support over those 3 years, putting this paper together was not the easiest but we did it! 🥳