Samuel Getachew

[Samuel Getachew @Sammygetachew]

Never been more important than now to prioritize #mentalhealth
The hardest thing about having mental health problem is that people may assume you are doing fine unlike physical illness.
Do listen others and express them selves.
Take care of your mental health❤❤❤

[Anthropic @AnthropicAI]

Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR.

We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use.

Read more: https://t.co/RuEosScSMb

[Sergiu P. Pasca @Sergiu_P_Pasca]

Today in @Nature, we report a new approach to studying human brain development and modeling disease in vivo.

Human neural #assembloids and #organoids have opened new ways to study development in vitro, but they also have important limitations. Transplantation can provide a more physiological environment, yet human cortical cells then develop within a rodent brain that matures much faster, constraining their growth and integration.

To address some of these limitations and obtain more advanced functional readouts relevant to disease biology, we generated #apallial mice, in which ~98% of the cortex and hippocampus fail to form, creating space for transplanted human cortical organoids to grow and integrate extensively.

We call these #xenocortical mice (XCX).

Nearly 7 years in the making. Congratulations to an extraordinary team and wonderful collaborators!

Link to the article below 👇

[Mario Nawfal @MarioNawfal]

🇮🇷 Iran’s president admitted the economic squeeze is hitting harder than the missiles.

Pezeshkian said the country is living through the “worst conditions” of economic warfare.

Everyone sees the missile exchanges, he noted, but the quieter financial pressures are just as real, and still the projects keep getting finished.

He framed it as proof of resilience while calling for more public support, official accountability, and private investment to push through.

With fresh U.S. sanctions ramping up, Tehran is openly acknowledging the pain while insisting the work doesn’t stop.

China remains the main buyer of Iranian oil and the quiet backstop that keeps revenue flowing outside Western systems, giving Tehran breathing room even as it tightens the country’s long-term dependence on a single partner.

Source: Anadolu Agency / Writer: Lucas

[Samuel Getachew @Sammygetachew]

@tinsae_tsegaye @MayoClinicGIHep @DougSimonetto @IrisWangMD Congratulations!!

[Tedros Adhanom Ghebreyesus @DrTedros]

#HIV is still one of the world’s deadliest health challenges — claiming over 44 million lives and counting.

But there is good news: we have new tools that can change the trajectory of the HIV epidemic. Lenacapavir — a long-acting injectable — is a game changer, shown to prevent almost all HIV infections among those at risk.

Now is the moment for global solidarity. I urge governments and partners to prioritize key and vulnerable populations, and make these life-changing tools accessible to everyone who needs them, everywhere.

#WorldAIDSday
#EndAIDS

https://t.co/OEWGwZfH24

[Samuel Getachew @Sammygetachew]

@Vic_Sereda @DrAkhilX In such massive ascites it could be hard to appreciate organomegaly with mere physical examination... so better to do USG Paracentesis.

[Samuel Getachew @Sammygetachew]

@DrAkhilX @Vic_Sereda What about in countries where there is a high burden of visceral leshmaniasis and malaria with HMS... where its common to have a huge splenomegaly... is it also better to do it on LLQ 🤔

[Sam Ghali, M.D. @EM_RESUS]

Here's a video I made breaking down this absolutely WILD Chest X-Ray you don't see every day

#FOAMed

[The Nobel Prize @NobelPrize]

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.

The Nobel Prize laureates identified the immune system’s security guards, regulatory T cells, thus laying the foundation for a new field of research. The discoveries have also led to the development of potential medical treatments that are now being evaluated in clinical trials.

The hope is to be able to treat or cure autoimmune diseases, provide more effective cancer treatments and prevent serious complications after stem cell transplants.

#NobelPrize

[Sam Ghali, M.D. @EM_RESUS]

Here's a video I made breaking down this incredible case of a 25-year-old woman who suddenly collapsed to the ground in cardiac arrest

#FOAMed

[Neuralink @neuralink]

Watch the latest update from the Neuralink team.

[Dr. Byomugabe ABRAHAM @RareHernia]

Ladies and Gentlemen. As you continue prescribing for yourself antibiotics, We are finished, actually we are cooked
#AMR

[Bill Gates @BillGates]

A big step forward in the fight against Alzheimer’s: The FDA approved the first blood test to help diagnose the disease. Breakthroughs like this will make earlier, easier diagnosis possible—bringing us closer to better treatments and, someday, a cure. https://t.co/Mf5T0EDHf0

[Samuel Getachew @Sammygetachew]

@AstewayGashaw @tadesse_eleni I should have considered that... Ginger and garlic (the usuals) would do the job😂

[Samuel Getachew @Sammygetachew]

@tweetofmicky Yo, those titles are mad cringey... Looks like all these corny clickbaits on his Youtube ain't anything new afterall.

[Samuel Getachew @Sammygetachew]

🌟 Huge thanks to the Neuralink team for their groundbreaking work on Blindsight! 🙌 can’t wait to see the positive impact this technology will have on lives around the world. Here’s to a future filled with possibilities! #Neuralink #Blindsight #Gratitude #Innovation

[Elon Musk @elonmusk]

The Blindsight device from Neuralink will enable even those who have lost both eyes and their optic nerve to see.

Provided the visual cortex is intact, it will even enable those who have been blind from birth to see for the first time.

To set expectations correctly, the vision will be at first be low resolution, like Atari graphics, but eventually it has the potential be better than natural vision and enable you to see in infrared, ultraviolet or even radar wavelengths, like Geordi La Forge.

Much appreciated, @US_FDA!

[Samuel Getachew @Sammygetachew]

@telebirr Telebirr remit

[Samuel Getachew @Sammygetachew]

@SofuSofu150188 @mrtweetusa Yiknash abate😂😂😂

[Samuel Getachew @Sammygetachew]

Substandard & falsified drugs constitute 20% of African market. Grave concern for patient safety & health outcomes w/h also undermines trust in Healthcare. This alarming statistic signifies urgent need for stronger regulatory measures & increased vigilance. #Healthcare #Pharmacy"

[Mario Nawfal @MarioNawfal]

���🇹 STUDY: 1 IN 5 MEDICINES IN AFRICA SUBSTANDARD OR FAKE | 1/2 MILLION DEATHS ANNUALLY

A major study finds that 20% of medicines in Africa are substandard or falsified, potentially causing 500,000 deaths annually.

Ethiopia's Bahir Dar University researchers revealed 1,639 out of 7,508 samples failed quality tests, highlighting antibiotics and antimalarials as the most commonly falsified.

Malawi has the highest proportion of these dangerous drugs, exacerbating antimicrobial resistance and treatment failures.

Source: The Guardian